WormBase Tree Display for Gene: WBGene00001961
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| WBGene00001961 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | F38C2 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | hlh-17 | Person_evidence | WBPerson346 | |||||
| Sequence_name | F38C2.2 | ||||||||
| Molecular_name | F38C2.2 | ||||||||
| F38C2.2.1 | |||||||||
| CE42757 | |||||||||
| Other_name | CELE_F38C2.2 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | hlh-17 | ||||||||
| DB_info | Database | AceView | gene | 4R15 | |||||
| WormQTL | gene | WBGene00001961 | |||||||
| WormFlux | gene | WBGene00001961 | |||||||
| NDB | locus_tag | CELE_F38C2.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001961|UniProtKB=O45489 | |||||||
| family | PTHR19290 | ||||||||
| NCBI | gene | 185460 | |||||||
| RefSeq | protein | NM_070527.6 | |||||||
| SwissProt | UniProtAcc | O45489 | |||||||
| UniProt_GCRP | UniProtAcc | O45489 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | hlh | ||||||||
| Allele (58) | |||||||||
| Strain | WBStrain00035812 | ||||||||
| WBStrain00040629 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (16) | |||||||||
| Ortholog (54) | |||||||||
| Paralog | WBGene00001960 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00003018 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00003595 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00013665 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00009540 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00000561 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | hlh-17 encodes a basic helix-loop-helix (bHLH) transcription factor that is most closely related to Drosophila and vertebrate Olig proteins; in C. elegans, HLH-17 is essential for larval development, egg-laying, and chemotaxis to potassium and sodium ions; an hlh-17::gfp promoter fusion is expressed in the cephalic sheath (CEPsh) glia at all developmental stages and some ventral nerve cord motorneurons; weak hlh-17::gfp reporter expression is also seen in developing embryos; HLH-17 expression in CEPsh glia is under the control of the VAB-3 and MLS-2 homeodomain proteins, as well as HLH-17 itself. | Paper_evidence | WBPaper00026651 | |||||
| WBPaper00031917 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 06 Jun 2008 00:00:00 | ||||||||
| Automated_description | Predicted to enable DNA-binding transcription factor activity and E-box binding activity. Involved in positive regulation of dopaminergic synaptic transmission and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in CEPshDL; CEPshDR; CEPshVL; CEPshVR; and ventral cord neurons. Is an ortholog of human BHLHE22 (basic helix-loop-helix family member e22) and BHLHE23 (basic helix-loop-helix family member e23). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F38C2.2 | |||||||
| Corresponding_CDS_history | F38C2.2:wp99 | ||||||||
| F38C2.2:wp192 | |||||||||
| Corresponding_transcript | F38C2.2.1 | ||||||||
| Associated_feature | WBsf978829 | ||||||||
| WBsf998838 | |||||||||
| WBsf229591 | |||||||||
| Transcription_factor | WBTranscriptionFactor000176 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00061130 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00061129 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00046700 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00061128 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr3311 | ||||||||
| Expr3312 | |||||||||
| Expr1021086 | |||||||||
| Expr1150581 | |||||||||
| Expr2012497 | |||||||||
| Expr2030736 | |||||||||
| Marker29 | |||||||||
| Drives_construct (19) | |||||||||
| Construct_product | WBCnstr00016016 | ||||||||
| WBCnstr00016202 | |||||||||
| WBCnstr00022555 | |||||||||
| WBCnstr00036558 | |||||||||
| Microarray_results (13) | |||||||||
| Expression_cluster (46) | |||||||||
| Interaction (32) | |||||||||
| Map_info | Map | IV | Position | 14.6216 | Error | 0.001273 | |||
| Positive | Positive_clone | F38C2 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4406 | |||||||
| 4621 | |||||||||
| 5290 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (17) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
