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WormBase Tree Display for Gene: WBGene00003134

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Name Class

WBGene00003134SMapS_parentSequenceF10C5
IdentityVersion4
NameCGC_namemat-3Person_evidenceWBPerson205
Sequence_nameF10C5.1
Molecular_nameF10C5.1
F10C5.1.1
CE26888
Other_namepod-4
apc-8
vex-2CGC_data_submission
cdc-23Paper_evidenceWBPaper00010392
szy-13Paper_evidenceWBPaper00049084
Person_evidenceWBPerson728
CELE_F10C5.1Accession_evidenceNDBBX284603
Public_namemat-3
DB_infoDatabaseAceViewgene3B99
WormQTLgeneWBGene00003134
WormFluxgeneWBGene00003134
NDBlocus_tagCELE_F10C5.1
PanthergeneCAEEL|WormBase=WBGene00003134|UniProtKB=Q19294
familyPTHR12558
NCBIgene175205
RefSeqproteinNM_064802.7
SwissProtUniProtAccQ19294
TREEFAMTREEFAM_IDTF101055
UniProt_GCRPUniProtAccQ19294
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:30WBPerson1971EventImportedInitial conversion from geneace
201 Mar 2006 08:09:39WBPerson2970EventAcquires_mergeWBGene00077741
Name_changeOther_namevex-2
307 May 2009 15:33:27WBPerson1847EventAcquires_mergeWBGene00000385
422 Jan 2016 08:31:00WBPerson2970EventAcquires_mergeWBGene00077741
Name_changeOther_nameszy-13
Acquires_mergeWBGene00000385
WBGene00077741
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classmat
Allele (163)
Possibly_affected_byWBVar02158830
Legacy_information[Golden A] Mutation is defective in metaphase to anaphase transition.
[Sundaram M] ku233 homozygotes exhibit abnormal vulval development, beginning with abnormal appearance of the Pn.pxx nuclei from both primary and secondary lineages.
Complementation_data[Sundaram M] Complements pat-4, pat-12
[] complements pat-4(st551), pat-12(st430), vab-6(e697)
StrainWBStrain00035408
WBStrain00035413
WBStrain00035706
WBStrain00037075
WBStrain00006406
WBStrain00006407
WBStrain00008573
RNASeq_FPKM (74)
GO_annotation (15)
Contained_in_operonCEOP3024
Ortholog (45)
ParalogWBGene00001281Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003132Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionmat-3 encodes a tetratricopeptide repeat (TPR)-containing protein that is the C. elegans ortholog of CDC23/APC8, a conserved regulatory subunit of the anaphase-promoting complex; mat-3 activity is required for progression through metaphase of oocyte meiosis I, germline proliferation, and vulval development.Paper_evidenceWBPaper00004484
WBPaper00005096
WBPaper00024252
WBPaper00028738
WBPaper00029251
Curator_confirmedWBPerson1843
Date_last_updated22 May 2007 00:00:00
Automated_descriptionPredicted to enable molecular adaptor activity. Involved in asymmetric cell division; polarity specification of anterior/posterior axis; and positive regulation of metaphase/anaphase transition of meiosis I. Predicted to be part of anaphase-promoting complex. Is an ortholog of human CDC23 (cell division cycle 23).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF10C5.1
Corresponding_transcriptF10C5.1.1
Other_sequence (25)
Associated_featureWBsf224368
WBsf224369
Experimental_infoRNAi_result (45)
Expr_patternExpr3590
Expr1025894
Expr1031479
Expr1148188
Expr2013392
Expr2031624
Construct_productWBCnstr00011514
Microarray_results (25)
Expression_cluster (130)
Interaction (112)
Map_infoMapIIIPosition-26.8403Error0.003928
PositivePositive_cloneF10C5Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_data2_point7120
Multi_point3924
3925
3926
4857
4824
3736
3735
Pos_neg_data10571
Reference (42)
RemarkSequence connection from [Golden A] krb 02/03/28
MethodGene