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WormBase Tree Display for Gene: WBGene00003252

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Name Class

WBGene00003252EvidenceCGC_data_submission
SMapS_parentSequenceF01F1
IdentityVersion2
NameCGC_namemig-21Person_evidenceWBPerson342
Sequence_nameF01F1.13
Molecular_nameF01F1.13
F01F1.13.1
CE48870
Other_nameCELE_F01F1.13Accession_evidenceNDBBX284603
Public_namemig-21
DB_infoDatabaseWormFluxgeneWBGene00003252
NDBlocus_tagCELE_F01F1.13
PanthergeneCAEEL|WormBase=WBGene00003252|UniProtKB=G1FC92
familyPTHR22906
NCBIgene184064
RefSeqproteinNM_001268004.4
SwissProtUniProtAccG1FC92
TREEFAMTREEFAM_IDTF317672
UniProt_GCRPUniProtAccG1FC92
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:31WBPerson1971EventImportedInitial conversion from geneace
225 Nov 2011 11:28:00WBPerson2970EventAcquires_mergeWBGene00017167
Name_changeSequence_nameF01F1.13
Acquires_mergeWBGene00017167
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classmig
Allele (20)
Legacy_information[Du H, Chalfie M ] u787 homozygotes exhibit abnormalities in migration of touch cells AVM and PVM, resulting from random initial migrations of QL and QR.
StrainWBStrain00035048
RNASeq_FPKM (74)
GO_annotation (16)
Ortholog (16)
ParalogWBGene00017379Caenorhabditis elegansFrom_analysisTreeFam
WBGene00017376Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00008851
WBGene00011880Caenorhabditis elegansFrom_analysisPanther
WBGene00017471Caenorhabditis elegansFrom_analysisPanther
WBGene00016468Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionmig-21 encodes a thrombospondin repeat-containing single-pass transmembrane protein; MIG-21 functions cell autonomously in the Q neuroblasts, and in parallel with UNC-40/DCC, to regulate the initial polarization and asymmetric migration of the Q neuroblasts and thus determine the threshold for EGL-20-mediated Wnt signaling that, in turn, regulates expression of mab-5 and the extent of posteriorly directed cell migration; mig-21 is transiently expressed in QL and QR during the L1 larval stage when the initial polarization and migration of the Q neuroblasts occurs and in body wall muscle throughout post-embryonic development.Paper_evidenceWBPaper00004685
WBPaper00040419
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated30 Nov 2011 00:00:00
Automated_descriptionPredicted to enable signaling receptor activity. Involved in several processes, including cell migration; determination of left/right asymmetry in nervous system; and regulation of canonical Wnt signaling pathway. Predicted to be located in plasma membrane. Expressed in QL; QR; and body wall musculature.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF01F1.13
Corresponding_CDS_historyF01F1.13a:wp239
F01F1.13b:wp275
Corresponding_transcriptF01F1.13.1
Associated_featureWBsf666936
WBsf666937
Experimental_infoRNAi_resultWBRNAi00101964Inferred_automaticallyRNAi_primary
WBRNAi00030538Inferred_automaticallyRNAi_primary
WBRNAi00043745Inferred_automaticallyRNAi_primary
WBRNAi00005368Inferred_automaticallyRNAi_primary
WBRNAi00012737Inferred_automaticallyRNAi_primary
Expr_patternExpr9684
Expr1147729
Expr2013567
Expr2031800
Drives_constructWBCnstr00015461
Construct_productWBCnstr00015461
Microarray_results (20)
Expression_cluster (78)
InteractionWBInteraction000524010
WBInteraction000524011
WBInteraction000554866
Anatomy_functionWBbtf0822
WBbtf0828
Map_infoMapIIIPosition-1.43748
PositivePositive_cloneF01F1Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4017
Reference (14)
RemarkData extracted from Du and Chalfie (2001)
Positive_clone is based on mutant sequence [030403 ck1]
MethodGene