WormBase Tree Display for Gene: WBGene00003504
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| WBGene00003504 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | ZK1098 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | mut-7 | Person_evidence | WBPerson261 | |||||
| Sequence_name | ZK1098.8 | ||||||||
| Molecular_name | ZK1098.8 | ||||||||
| ZK1098.8.1 | |||||||||
| CE00370 | |||||||||
| Other_name | CELE_ZK1098.8 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | mut-7 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:32 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | mut | ||||||||
| Allele (46) | |||||||||
| Strain | WBStrain00003332 | ||||||||
| WBStrain00028942 | |||||||||
| WBStrain00028975 | |||||||||
| WBStrain00034635 | |||||||||
| WBStrain00040468 | |||||||||
| In_cluster | conserved_miRNA_siRNA_cluster | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (24) | |||||||||
| Ortholog (28) | |||||||||
| Paralog | WBGene00014220 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00013256 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| WBGene00012290 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| Structured_description | Concise_description | mut-7 encodes a homolog of RnaseD that represses transposition of Tc1, Tc3, Tc4, and Tc5, perhaps by degrading transposon-specific messages; also affects sperm development, sensitivity to RNAi of mainly germline expressed genes, silencing of some germline transgenes, X chromosome loss, and is required for cosuppression (functional silencing of chromosomal loci induced by transgenes) and for silencing induced by antisense RNA oligomers; cellular fractionation experiments indicate that MUT-7 is expressed in adult worms, and resides in a complex in both the cytosol and nucleus; in the cytosolic complex, MUT-7 interacts with RDE-2, a novel protein also required for RNA interference. | Paper_evidence | WBPaper00003711 | |||||
| WBPaper00003722 | |||||||||
| WBPaper00003956 | |||||||||
| WBPaper00004198 | |||||||||
| WBPaper00005077 | |||||||||
| WBPaper00024699 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 28 Dec 2005 00:00:00 | ||||||||
| Automated_description | Predicted to enable 3'-5'-exoribonuclease activity involved in mature miRNA 3'-end processing. Involved in obsolete negative regulation of transposition, DNA-mediated; olfactory learning; and regulatory ncRNA-mediated post-transcriptional gene silencing. Located in cytosol; mutator focus; and nucleus. Expressed in AWCL; AWCR; and somatic cell. Is an ortholog of human EXD3 (exonuclease 3'-5' domain containing 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | ZK1098.8 | |||||||
| Corresponding_transcript | ZK1098.8.1 | ||||||||
| Other_sequence | CR03715 | ||||||||
| CBC14770_1 | |||||||||
| CRC08288_1 | |||||||||
| Associated_feature | WBsf667292 | ||||||||
| WBsf667293 | |||||||||
| WBsf227313 | |||||||||
| Experimental_info | RNAi_result (12) | ||||||||
| Expr_pattern (11) | |||||||||
| Drives_construct | WBCnstr00003803 | ||||||||
| WBCnstr00014695 | |||||||||
| WBCnstr00014696 | |||||||||
| WBCnstr00018512 | |||||||||
| WBCnstr00036084 | |||||||||
| Construct_product | WBCnstr00014695 | ||||||||
| WBCnstr00014696 | |||||||||
| WBCnstr00018512 | |||||||||
| WBCnstr00036084 | |||||||||
| Antibody | WBAntibody00000828 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (133) | |||||||||
| Interaction (31) | |||||||||
| WBProcess | WBbiopr:00000057 | ||||||||
| Map_info | Map | III | Position | 0.579676 | Error | 0.00167 | |||
| Positive | Positive_clone | ZK1098 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4504 | |||||||
| 4993 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (129) | |||||||||
| Remark | Sequence connection from [Ketting RF] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
