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WormBase Tree Display for Gene: WBGene00003838

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Name Class

WBGene00003838SMapS_parentSequenceCHROMOSOME_V
IdentityVersion1
NameCGC_nameocr-1Person_evidenceWBPerson42
Sequence_nameF28H7.10
Molecular_nameF28H7.10a
F28H7.10a.1
CE51877
F28H7.10b
CE40048
F28H7.10b.1
Other_nameCELE_F28H7.10Accession_evidenceNDBBX284605
Public_nameocr-1
DB_infoDatabaseWormQTLgeneWBGene00003838
WormFluxgeneWBGene00003838
NDBlocus_tagCELE_F28H7.10
PanthergeneCAEEL|WormBase=WBGene00003838|UniProtKB=G5EDR9
familyPTHR10582
NCBIgene185101
RefSeqproteinNM_001047642.1
NM_001348583.2
TREEFAMTREEFAM_IDTF314711
TrEMBLUniProtAccQ1NZ21
G5EDR9
UniProt_GCRPUniProtAccG5EDR9
OMIMgene606680
607066
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:33WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classocr
Allele (52)
StrainWBStrain00026384
WBStrain00026393
WBStrain00026395
WBStrain00005262
WBStrain00005263
WBStrain00007483
RNASeq_FPKM (74)
GO_annotation (12)
Ortholog (37)
ParalogWBGene00003889Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00003839Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00003840Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00003841Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionocr-1 encodes a transient receptor potential (TRP) channel; an OCR-1::GFP reporter fusion is expressed in the amphid sensory neurons AWA and ADL.Paper_evidenceWBPaper00005350
Curator_confirmedWBPerson1843
Date_last_updated18 May 2012 00:00:00
Automated_descriptionEnables temperature-gated cation channel activity. Involved in heat acclimation. Predicted to be located in membrane. Expressed in ADLL; ADLR; AWAL; and AWAR. Human ortholog(s) of this gene implicated in several diseases, including keratosis (multiple); migraine with aura; and rosacea. Is an ortholog of human TRPV5 (transient receptor potential cation channel subfamily V member 5) and TRPV6 (transient receptor potential cation channel subfamily V member 6).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:9256Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:18084)
DOID:10024Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:18084)
DOID:11714Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:14006,HGNC:3145)
DOID:10591Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:14006,HGNC:3145)
DOID:0112013Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:18084)
DOID:13543Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:14006)
DOID:8881Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:18084)
DOID:0111711Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:18084)
DOID:0050534Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:18084)
DOID:5419Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:18084)
Molecular_infoCorresponding_CDSF28H7.10a
F28H7.10b
Corresponding_CDS_historyF28H7.10a:wp176
F28H7.10a:wp257
Corresponding_transcriptF28H7.10a.1
F28H7.10b.1
Other_sequenceMIC04495_1
Acan_isotig12849
Oden_isotig13002
JI180503.1
Oden_isotig13004
Dviv_isotig27670
Oden_isotig24097
MI05202
Oden_isotig13003
Experimental_infoRNAi_resultWBRNAi00045878Inferred_automaticallyRNAi_primary
WBRNAi00014080Inferred_automaticallyRNAi_primary
Expr_patternExpr1982
Expr15394
Expr1018073
Expr1149782
Expr2014596
Expr2032829
Drives_constructWBCnstr00010556
WBCnstr00035842
Construct_productWBCnstr00010556
WBCnstr00035842
Microarray_results (22)
Expression_cluster (48)
InteractionWBInteraction000052665
WBInteraction000052913
WBInteraction000169538
WBInteraction000169577
WBInteraction000388238
WBInteraction000518011
WBInteraction000518012
WBInteraction000518013
Map_infoMapVPosition2.75796Error0.001756
PositivePositive_cloneF28H7Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4554
Pseudo_map_position
Reference (22)
RemarkGene name created on basis of email from [Schwarz E], citing paper by [Tobin DM] et al. [krb 020721]
MethodGene