WormBase Tree Display for Gene: WBGene00003840
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| WBGene00003840 | SMap | S_parent | Sequence | T10B10 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | ocr-3 | Person_evidence | WBPerson42 | |||||
| Sequence_name | T10B10.7 | ||||||||
| Molecular_name | T10B10.7 | ||||||||
| T10B10.7.1 | |||||||||
| CE40872 | |||||||||
| Other_name | CELE_T10B10.7 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | ocr-3 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ocr | ||||||||
| Allele (69) | |||||||||
| Strain | WBStrain00032073 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00075121 | ||||||||
| 00075122 | |||||||||
| 00075123 | |||||||||
| 00075124 | |||||||||
| 00111890 | |||||||||
| 00111891 | |||||||||
| 00111892 | |||||||||
| 00111893 | |||||||||
| Ortholog (35) | |||||||||
| Paralog | WBGene00003838 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00003839 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00003889 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00003841 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | ocr-3 encodes a predicted TRPV channel (transient receptor potential cation channel, subfamily V) containing six membrane-spanning regions, cytoplasmic ankyrin repeats, and a long, unconserved cytoplasmic tail that is related to the mammalian TRPV1 cation channel (OMIM:602076) activated by capsaicin and other noxious stimuli; although the precise role of OCR-3 in C. elegans development and/or behavior is not yet known, OCR-3 expression is detected solely in the rectal gland cells and occasionally the glial socket cells of the head, suggesting that OCR-3 may function in sensory signal transduction in these cell types. | Paper_evidence | WBPaper00005350 | |||||
| WBPaper00017555 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable monoatomic ion channel activity. Predicted to be involved in monoatomic ion transmembrane transport. Predicted to be located in membrane. Expressed in rectal gland cell and socket cell. Human ortholog(s) of this gene implicated in hyperparathyroidism. Is an ortholog of human TRPV5 (transient receptor potential cation channel subfamily V member 5) and TRPV6 (transient receptor potential cation channel subfamily V member 6). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:13543 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:14006) | ||||
| DOID:11714 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:14006,HGNC:3145) | ||||||
| DOID:10591 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:14006,HGNC:3145) | ||||||
| Molecular_info | Corresponding_CDS | T10B10.7 | |||||||
| Corresponding_CDS_history | T10B10.7:wp83 | ||||||||
| T10B10.7:wp102 | |||||||||
| T10B10.7:wp124 | |||||||||
| T10B10.7:wp174 | |||||||||
| Corresponding_transcript | T10B10.7.1 | ||||||||
| Other_sequence | CBC09403_1 | ||||||||
| CJC01313_1 | |||||||||
| Oden_isotig28114 | |||||||||
| Dviv_isotig25225 | |||||||||
| Associated_feature | WBsf1008117 | ||||||||
| WBsf1008118 | |||||||||
| WBsf1024527 | |||||||||
| WBsf236750 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00052991 | Inferred_automatically | RNAi_primary | |||||
| Expr_pattern | Expr1984 | ||||||||
| Expr1020944 | |||||||||
| Expr1156594 | |||||||||
| Expr2014598 | |||||||||
| Expr2032831 | |||||||||
| Drives_construct | WBCnstr00010558 | ||||||||
| WBCnstr00035840 | |||||||||
| Construct_product | WBCnstr00010558 | ||||||||
| WBCnstr00035840 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (74) | |||||||||
| Interaction (31) | |||||||||
| Map_info | Map | X | Position | 22.2613 | Error | 0.054562 | |||
| Positive | Positive_clone | T10B10 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 5136 | |||||||
| 4459 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (14) | |||||||||
| Remark | Gene name created on basis of email from [Schwarz E], citing paper by [Tobin DM] et al. [krb 020721] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
