WormBase Tree Display for Gene: WBGene00004746

WBGene00004746 SMap: S_parent: Sequence: CHROMOSOME_X
  Identity: Version: 1
    Name: CGC_name: sdc-2 Person_evidence: WBPerson421
      Sequence_name: C35C5.1
      Molecular_name: C35C5.1
        C35C5.1.1
        CE18542
      Other_name: CELE_C35C5.1 Accession_evidence: NDB BX284606
      Public_name: sdc-2
    DB_info: Database: AceView gene XM151
        WormQTL gene WBGene00004746
        WormFlux gene WBGene00004746
        NDB locus_tag CELE_C35C5.1
        Panther gene CAEEL|WormBase=WBGene00004746|UniProtKB=G5EBL3
          family PTHR13270
        NCBI gene 181341
        RefSeq protein NM_077523.7
        SwissProt UniProtAcc G5EBL3
        TREEFAM TREEFAM_ID TF350609
        UniProt_GCRP UniProtAcc G5EBL3
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:36 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: sdc
    Allele (134)
    Legacy_information: See also y15
      [C.elegansII] y15 : XX animals inviable and masculinized, XO animals WT. No maternal rescue. ES3 (XX); ME3.OA>20: y46, y74, y55 (weaker, Egl or Tra phenotypes). ???Cloned: 9.2 kb transcript, encodes predicted 2962 protein (344 kD), highly charged. [Nusbaum and Meyer 1989; TY]
    Strain: WBStrain00035098
      WBStrain00035100
      WBStrain00035166
      WBStrain00035105
    RNASeq_FPKM (74)
    GO_annotation: 00009802
      00009803
      00009804
      00009805
      00009806
      00009807
      00009808
    Ortholog (33)
    Paralog: WBGene00018316 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: The sdc-2 gene encodes a protein that represses transcription of X chromosomes to achieve dosage compensation, and that also represses the male sex-determination gene her-1 to elicit hermaphrodite differentiation. Paper_evidence: WBPaper00005215
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Involved in dosage compensation by hypoactivation of X chromosome and negative regulation of transcription by RNA polymerase II. Located in nuclear chromosome. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C35C5.1
    Corresponding_transcript: C35C5.1.1
    Other_sequence: AF111934
    Associated_feature (9)
    Gene_product_binds: WBsf019092
      WBsf019093
    Transcription_factor: WBTranscriptionFactor000093
      WBTranscriptionFactor000689
  Experimental_info: RNAi_result (35)
    Expr_pattern: Expr10429
      Expr11875
      Expr1028636
      Expr1032344
      Expr1145975
      Expr2015659
      Expr2033892
    Drives_construct: WBCnstr00006791
      WBCnstr00015322
      WBCnstr00035415
    Construct_product: WBCnstr00005103
      WBCnstr00005104
      WBCnstr00006790
      WBCnstr00006791
      WBCnstr00035415
    Antibody: WBAntibody00000228
      WBAntibody00000496
      WBAntibody00000497
      WBAntibody00001184
      WBAntibody00002039
      WBAntibody00002042
      WBAntibody00002043
    Microarray_results (21)
    Expression_cluster (134)
    Interaction (77)
    WBProcess: WBbiopr:00000056
  Map_info: Map: X Position: 4.34757 Error: 0.06798
    Well_ordered
    Positive: Inside_rearr: yDp7
      Positive_clone: C03B2
        C35C5 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 1438
        1439
        1440
        1774
        2062
        2293
        3319
        3642
        3643
        3687
      Pos_neg_data (11)
    Landmark_gene
  Reference: WBPaper00001077
    WBPaper00001116
    WBPaper00001171
    WBPaper00001206
    WBPaper00001242
    WBPaper00001279
    WBPaper00001341
    WBPaper00001412
    WBPaper00001416
    WBPaper00001473
    WBPaper00001513
    WBPaper00001544
    WBPaper00001554
    WBPaper00001609
    WBPaper00001679
    WBPaper00001683
    WBPaper00001687
    WBPaper00001691
    WBPaper00001708
    WBPaper00001772
    WBPaper00001955
    WBPaper00001966
    WBPaper00001971
    WBPaper00001982
    WBPaper00001991
    WBPaper00002074
    WBPaper00002107
    WBPaper00002131
    WBPaper00002278
    WBPaper00002302
    WBPaper00002303
    WBPaper00002304
    WBPaper00002347
    WBPaper00002605
    WBPaper00002606
    WBPaper00002631
    WBPaper00002743
    WBPaper00002765
    WBPaper00003075
    WBPaper00003213
    WBPaper00003262
    WBPaper00003279
    WBPaper00003557
    WBPaper00004130
    WBPaper00004158
    WBPaper00004256
    WBPaper00004467
    WBPaper00005215
    WBPaper00005221
    WBPaper00005237
    WBPaper00005549
    WBPaper00005643
    WBPaper00006355
    WBPaper00010744
    WBPaper00013716
    WBPaper00013718
    WBPaper00013841
    WBPaper00013842
    WBPaper00014003
    WBPaper00014084
    WBPaper00014086
    WBPaper00014182
    WBPaper00014204
    WBPaper00014218
    WBPaper00014842
    WBPaper00014926
    WBPaper00015147
    WBPaper00015288
    WBPaper00015362
    WBPaper00016770
    WBPaper00016921
    WBPaper00016993
    WBPaper00017113
    WBPaper00017114
    WBPaper00017234
    WBPaper00017243
    WBPaper00017255
    WBPaper00017260
    WBPaper00017261
    WBPaper00017324
    WBPaper00017470
    WBPaper00017484
    WBPaper00018402
    WBPaper00018694
    WBPaper00018702
    WBPaper00020898
    WBPaper00020995
    WBPaper00021041
    WBPaper00022075
    WBPaper00022128
    WBPaper00022230
    WBPaper00022499
    WBPaper00022895
    WBPaper00023040
    WBPaper00023050
    WBPaper00023141
    WBPaper00023992
    WBPaper00024121
    WBPaper00024123
    WBPaper00024248
    WBPaper00025000
    WBPaper00026779
    WBPaper00027240
    WBPaper00027248
    WBPaper00027297
    WBPaper00027309
    WBPaper00027993
    WBPaper00028816
    WBPaper00029211
    WBPaper00030931
    WBPaper00031121
    WBPaper00032450
    WBPaper00034553
    WBPaper00035023
    WBPaper00035408
    WBPaper00035968
    WBPaper00038180
    WBPaper00038880
    WBPaper00039724
    WBPaper00043168
    WBPaper00044301
    WBPaper00044491
    WBPaper00047963
    WBPaper00048365
    WBPaper00048375
    WBPaper00049531
    WBPaper00051302
    WBPaper00051429
    WBPaper00052419
    WBPaper00053662
    WBPaper00055155
    WBPaper00055604
    WBPaper00062335
    WBPaper00063325
    WBPaper00064630
  Method: Gene