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WormBase Tree Display for Gene: WBGene00006374

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Name Class

WBGene00006374EvidencePaper_evidenceWBPaper00003608
SMapS_parentSequenceT01B11
IdentityVersion2
NameCGC_namesyx-4Person_evidenceWBPerson3132
WBPerson203
Sequence_nameT01B11.3
Molecular_nameT01B11.3
T01B11.3.1
CE43759
Other_namesyn-4Person_evidenceWBPerson203
CELE_T01B11.3Accession_evidenceNDBBX284604
Public_namesyx-4
DB_infoDatabaseAceViewgene4J223
WormQTLgeneWBGene00006374
WormFluxgeneWBGene00006374
NDBlocus_tagCELE_T01B11.3
PanthergeneCAEEL|WormBase=WBGene00006374|UniProtKB=P91409
familyPTHR19957
NCBIgene177647
RefSeqproteinNM_069038.4
SwissProtUniProtAccP91409
UniProt_GCRPUniProtAccP91409
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:40WBPerson1971EventImportedInitial conversion from geneace
216 Apr 2010 14:03:06WBPerson2970Name_changeCGC_namesyx-4
Other_namesyn-4
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classsyx
Allele (27)
StrainWBStrain00035562
RNASeq_FPKM (74)
GO_annotation (26)
Ortholog (31)
ParalogWBGene00006371Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00006372Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00006373Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00006798Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00022534Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00009478Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00012150Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionsyx-4 encodes a syntaxin-related t-SNARE; t-SNARES function as receptor for intracellular transport vesicles during membrane fusion reactions and in C. elegans, SYX-4 activity is essential for three aspects of early embryogenesis: polar body extrusion, cytokinesis, and nuclear envelope reassembly following mitosis; in addition, SYX-4 plays a role in formation of the vitelline membrane and/or eggshell, as SYX-4 is required for regulated secretion of CAV-1-containing cortical granules following fertilization; SYX-4 is expressed in cortical granules, the outer membrane of the early embryo, in a punctate pattern around reforming nuclear envelopes, and at the cleavage furrow during ingression; in L1 larvae, SYX-4 is expressed at high levels in lateral seam cells, and in adult hermaphrodites SYX-4 localizes to the incomplete membranes that separate germline nuclei in the gonad.Paper_evidenceWBPaper00003608
WBPaper00032152
Curator_confirmedWBPerson1843
Date_last_updated17 Feb 2011 00:00:00
Automated_descriptionPredicted to enable SNAP receptor activity and SNARE binding activity. Involved in cortical granule exocytosis; positive regulation of cytokinesis; and regulation of exocytosis. Located in cleavage furrow; cortical granule; and perinuclear region of cytoplasm. Expressed in gonad and seam cell.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDST01B11.3
Corresponding_CDS_historyT01B11.3:wp203
Corresponding_transcriptT01B11.3.1
Other_sequence (13)
Associated_featureWBsf228680
Experimental_infoRNAi_result (13)
Expr_patternExpr2735
Expr8957
Expr1019951
Expr1032572
Expr1155703
Expr2017194
Expr2035330
Drives_constructWBCnstr00005708
WBCnstr00005929
WBCnstr00009555
WBCnstr00037915
Construct_productWBCnstr00005708
WBCnstr00005929
WBCnstr00008648
WBCnstr00009555
WBCnstr00010925
WBCnstr00037915
AntibodyWBAntibody00000234
WBAntibody00001736
Microarray_results (19)
Expression_cluster (128)
Interaction (60)
Map_infoMapIVPosition3.81268Error0.006521
PositivePositive_cloneT01B11Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5430
Pseudo_map_position
Reference (13)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene