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WormBase Tree Display for Gene: WBGene00006749

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Name Class

WBGene00006749SMapS_parentSequenceCHROMOSOME_X
IdentityVersion1
NameCGC_nameunc-9Person_evidenceWBPerson261
Sequence_nameR12H7.1
Molecular_nameR12H7.1a
R12H7.1a.1
CE28246
R12H7.1b
CE51729
R12H7.1a.2
R12H7.1b.1
Other_nameCELE_R12H7.1Accession_evidenceNDBBX284606
Public_nameunc-9
DB_infoDatabaseAceViewgeneXN833
WormQTLgeneWBGene00006749
WormFluxgeneWBGene00006749
NDBlocus_tagCELE_R12H7.1
PanthergeneCAEEL|WormBase=WBGene00006749|UniProtKB=O01393
familyPTHR11893
NCBIgene181443
RefSeqproteinNM_001330917.4
NM_171790.8
SwissProtUniProtAccO01393
TrEMBLUniProtAccA0A1C3NSM1
UniProt_GCRPUniProtAccO01393
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:41WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classunc
Reference_alleleWBVar00142960
AlleleWBVar02148980Inferred_automaticallyFrom strain object: CGC135
From strain object: FX30194
From strain object: FX30252
From strain object: GR3055
WBVar00145315Inferred_automaticallyFrom strain object: CW129
From strain object: ZM3087
WBVar00145090Inferred_automaticallyFrom strain object: FH85
WBVar02148979Inferred_automaticallyFrom strain object: FX30186
From strain object: FX30253
WBVar02148982Inferred_automaticallyFrom strain object: FX30237
WBVar00087927Inferred_automaticallyFrom strain object: HH29
WBVar00087928Inferred_automaticallyFrom strain object: HH31
WBVar00087929Inferred_automaticallyFrom strain object: HH35
WBVar02147666
WBVar00296463
WBVar00142968
WBVar01199867
WBVar01199868
WBVar01199869
WBVar01499887
WBVar01199870
WBVar01499519
WBVar01199871
WBVar01499888
WBVar01199872
WBVar01199873
WBVar02013690
WBVar02013691
WBVar01199874
WBVar01199875
WBVar02013692
WBVar01199876
WBVar02113246
WBVar01199877
WBVar01499710
WBVar02077142
WBVar01199878
WBVar01199879
WBVar01199880
WBVar01199881
WBVar01199882
WBVar01199883
WBVar02140355
WBVar00101343
WBVar01703522
WBVar01199884
WBVar02140356
WBVar01703523
WBVar02140357
WBVar00101344
WBVar01199885
WBVar00101345
WBVar01199886
WBVar02140358
WBVar01703524
WBVar01703525
WBVar01199887
WBVar00101346
WBVar01199888
WBVar01703526
WBVar00101347
WBVar01199889
WBVar01703527
WBVar00101348
WBVar01199890
WBVar01703528
WBVar00101349
WBVar01199891
WBVar01703529
WBVar01703530
WBVar02101667
WBVar01199892
WBVar02101668
WBVar01703531
WBVar01199893
WBVar01703532
WBVar01199894
WBVar02101669
WBVar01703533
WBVar01199895
WBVar01703534
WBVar01199896
WBVar01199897
WBVar01703535
WBVar01199898
WBVar01703536
WBVar01703537
WBVar00600866
WBVar01199899
WBVar01889204
WBVar01703538
WBVar01199900
WBVar01703539
WBVar01199901
WBVar01199902
WBVar01703540
WBVar01199903
WBVar01703541
WBVar01703542
WBVar01199904
WBVar01703543
WBVar01199905
WBVar01703544
WBVar01199906
WBVar01703545
WBVar01199907
WBVar01703546
WBVar01199908
WBVar01199909
WBVar00257667
WBVar01759756
WBVar01703547
WBVar01199910
WBVar01703548
WBVar01759757
WBVar01199911
WBVar01759758
WBVar01199912
WBVar01759759
WBVar01199913
WBVar00258407
WBVar01759760
WBVar01759761
WBVar01199914
WBVar01759762
WBVar01199915
WBVar01199916
WBVar01199917
WBVar01199918
WBVar01199919
WBVar01199920
WBVar01199921
WBVar01199922
WBVar01199923
WBVar01199924
WBVar01199925
WBVar01199926
WBVar01199927
WBVar01199928
WBVar00265230
WBVar01199929
WBVar01199930
WBVar01199931
WBVar01199932
WBVar01199933
WBVar01199934
WBVar01199935
WBVar01199936
WBVar01199937
WBVar01199938
WBVar01199939
WBVar01499957
WBVar01199940
WBVar01199941
WBVar01499958
WBVar00142960
WBVar01199942
WBVar01199943
WBVar01199944
WBVar01199945
WBVar01199946
WBVar01199947
WBVar01199948
WBVar01199949
WBVar01199950
WBVar01199951
WBVar01199952
WBVar01199953
WBVar01199954
WBVar02027512
WBVar01199955
WBVar00066314
WBVar01199956
WBVar01199957
WBVar01199958
WBVar01199959
WBVar02011216
WBVar02011217
WBVar01199960
WBVar01199961
WBVar02005320
WBVar01199962
WBVar01199963
WBVar02005321
WBVar02048824
WBVar02005322
WBVar01199964
WBVar01199965
WBVar02005323
WBVar02005324
WBVar02005325
WBVar00237171
WBVar00237172
WBVar00237173
WBVar01572252
WBVar00237174
WBVar01572253
WBVar00521322
WBVar00521323
WBVar00521324
WBVar01691431
WBVar00521325
WBVar01691432
WBVar00521326
WBVar01691433
WBVar01691434
WBVar01679073
WBVar00521327
WBVar01691435
WBVar01941614
WBVar01679074
WBVar00521328
WBVar01679075
WBVar01941615
WBVar01691436
WBVar00521329
WBVar01679076
WBVar01691437
WBVar00521330
WBVar01941616
WBVar00521331
WBVar01941617
WBVar01679077
WBVar01691438
WBVar01941618
WBVar01679078
WBVar00521332
WBVar01941619
WBVar01679079
WBVar00521333
WBVar01941620
WBVar01679080
WBVar00521334
WBVar01679081
WBVar00521335
WBVar01941621
WBVar01679082
WBVar01941622
WBVar00521336
WBVar00521337
WBVar01941623
WBVar01941624
WBVar00521338
WBVar00521339
WBVar00521340
WBVar00521341
WBVar00521342
WBVar00521343
WBVar00083966
WBVar00521344
WBVar00521345
WBVar00521346
WBVar00521347
WBVar00521348
WBVar02009393
WBVar00521349
WBVar00521350
WBVar00234080
WBVar00521351
WBVar00521352
WBVar00234081
WBVar00521353
WBVar00521354
WBVar01954982
WBVar00521355
WBVar01954983
WBVar00521356
WBVar01544579
WBVar01954984
WBVar01954985
WBVar01544580
WBVar01544581
WBVar01544582
WBVar01471965
WBVar01544583
WBVar01471967
WBVar00216734
WBVar00216735
WBVar02046650
WBVar00216736
WBVar00216738
WBVar00216739
WBVar00216740
WBVar00216741
WBVar00216742
WBVar00216743
WBVar00216744
WBVar00216745
WBVar01199854
WBVar00216746
WBVar01199855
WBVar00216747
WBVar01199856
WBVar01497297
WBVar01199857
WBVar01199858
WBVar01199859
WBVar01199860
WBVar01199861
WBVar01199862
WBVar01498960
WBVar01835253
WBVar01199863
WBVar01199864
WBVar01835254
WBVar01835255
WBVar01199865
WBVar01500067
WBVar01199866
Legacy_informatione101 : moves backward better than forward slight kinker in forward movement active healthy; larvae more severely uncoordinated; male fan slightly reduced spicules tend to protrude. ES2 ME0. NA2 (e111).
[C.elegansII] e101 : moves backward better than forward slight kinker in forward movement active healthy; larvae more severely uncoordinated; suppresses anaesthetic hypersensitivity of unc-79 and unc-80; male fan slightly reduced, spicules tend to protrude. ES2 ME0. OA3: e101, ec27, bx5, e111. Cloned: cosmid rescue (R12H7). [Brenner 1974; Morgan and Sedensky 1994; CW; MQ]
Strain (29)
RNASeq_FPKM (74)
GO_annotation (27)
Ortholog (35)
Paralog (24)
Structured_descriptionConcise_descriptionunc-9 encodes an innexin, an integral transmembrane channel protein that is a structural component of invertebrate gap junctions; UNC-9 is required for normal forward locomotion and egg-laying and also plays a role in the response to antihelminthics and volatile anesthetics; UNC-9 may form a functional pair with UNC-7, another C. elegans innexin, as mutations in unc-7 result in defects nearly identical to those in unc-9 mutant animals.Paper_evidenceWBPaper00002950
WBPaper00004670
WBPaper00005286
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnables actin filament binding activity and gap junction channel activity. Involved in monoatomic ion transmembrane transport and positive regulation of locomotion. Located in gap junction. Expressed in several structures, including anchor cell; muscle cell; neurons; phasmid sheath cell; and somatic nervous system.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSR12H7.1a
R12H7.1b
Corresponding_CDS_historyR12H7.1:wp52
Corresponding_transcriptR12H7.1a.1
R12H7.1a.2
R12H7.1b.1
Other_sequence (38)
Associated_feature (22)
Experimental_infoRNAi_resultWBRNAi00089959Inferred_automaticallyRNAi_primary
WBRNAi00027706Inferred_automaticallyRNAi_primary
WBRNAi00101970Inferred_automaticallyRNAi_primary
WBRNAi00090119Inferred_automaticallyRNAi_primary
WBRNAi00101969Inferred_automaticallyRNAi_primary
WBRNAi00101971Inferred_automaticallyRNAi_primary
WBRNAi00051863Inferred_automaticallyRNAi_primary
WBRNAi00090277Inferred_automaticallyRNAi_primary
WBRNAi00089762Inferred_automaticallyRNAi_primary
Expr_pattern (11)
Drives_constructWBCnstr00005223
WBCnstr00011756
WBCnstr00012540
WBCnstr00013463
WBCnstr00016962
WBCnstr00018785
WBCnstr00019879
WBCnstr00034174
WBCnstr00042717
Construct_productWBCnstr00004912
WBCnstr00007077
WBCnstr00014822
WBCnstr00017891
WBCnstr00018129
WBCnstr00019880
WBCnstr00021094
WBCnstr00022772
WBCnstr00022774
WBCnstr00034174
AntibodyWBAntibody00001277
WBAntibody00001907
Microarray_results (20)
Expression_clusterWBPaper00005700:transmembrane_protein
WBPaper00031040:TGF-beta_adult_upregulated
WBPaper00033065:clk-1(qm30)_upregulated
WBPaper00033065:cyc-1(RNAi)_upregulated
WBPaper00036375:enriched_in_PVD_OLL
WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
WBPaper00037950:A-class-motor-neurons_larva_enriched
WBPaper00037950:all-neurons_larva_enriched
WBPaper00037950:AVA-neuron_L1-larva_expressed
WBPaper00037950:AVE-neuron_L1-larva_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_CoreEnriched
WBPaper00037950:dopaminergic-neurons_embryo_enriched
WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:dopaminergic-neurons_larva_enriched
WBPaper00037950:GABAergic-motor-neurons_embryo_enriched
WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
WBPaper00037950:glr-1(+)-neurons_larva_enriched
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
WBPaper00040420:FLP_enriched
WBPaper00040560:hpl-2_embryo_upregulated
WBPaper00044656:tatn-1(qd182)_upregulated
WBPaper00044736:flat_dev_expression
WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
WBPaper00045974:NSM_enriched_totalRNA_RNAseq
WBPaper00045974:NSM_enriched_totalRNA_tiling
WBPaper00046509:htz-1(ok3099)_downregulated
WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
WBPaper00048988:neuron_enriched
WBPaper00048988:neuron_expressed
WBPaper00049545:cco-1(RNAi)_upregulated
WBPaper00049545:jmjd-3.1(+)_upregulated
WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
WBPaper00050053:muscle_enriched_Day4
WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_24-cell-embryo
WBPaper00050163:let-418(RNAi)_upregulated_24-cell-embryo
WBPaper00050163:let-418(RNAi)_upregulated_100-cell-embryo
WBPaper00050370:dpy-21(e428)_L3_upregulated
WBPaper00050412:cco-1(RNAi)_upregulated_N2
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050726:OsmoticStress_regulated_NoFood
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00050990:pharynx_expressed
WBPaper00051404:alg-1(gk214)_upregulated
WBPaper00051404:alg-2(ok304)_upregulated
WBPaper00052884:emb-4(hc60)_upregulated
WBPaper00053184:sma-2(rax5)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053302:stavudine_24h_regulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053321:PGCs_depleted_NuGen
WBPaper00053388:dauer_regulated_Cluster4
WBPaper00054758:alg-1(gk204)_upregulated
WBPaper00055354:eat-2(ad1116)_upregulated
WBPaper00055354:Rapamycin-Allantoin_downregulated
WBPaper00055482:Tunicamycin_downregulated
WBPaper00055565:AVK_enriched
WBPaper00055626:pry-1(mu38)_downregulated
WBPaper00055971:nhl-2(ok818)_25C_downregulated
WBPaper00056034:pals-22(jy3)_upregulated
WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
WBPaper00056090:E.faecalis_upregulated_N2
WBPaper00056443:sek-1(km4)_upregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056826:hmc_biased
WBPaper00058598:mex-1(or286)_upregulated
WBPaper00058598:mex-3(eu149)_upregulated
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00058598:spn-4(tm291)_upregulated
WBPaper00058711:paraquat_downregulated
WBPaper00058969:RIS_enriched
WBPaper00059027:neuron-synapses_depleted
WBPaper00059421:daf-1(m40);daf-3(mgDf90)_downregulated
WBPaper00059421:daf-3(mgDf90)_downregulated
WBPaper00059471:EGL-43_interacting
WBPaper00059566:wdr-23(mac32)_upregulated
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00059763:neuron_expressed
WBPaper00060014:set-2(tm1630)_downregulated
WBPaper00060459:bcat-1(RNAi)_upregulated
WBPaper00060661:sensory-neuron_enriched
WBPaper00060811:L1_vs_adult_upregulated_neural
WBPaper00060909:atfs-1(cmh15)_downregulated
WBPaper00061007:HB101_upregulated
WBPaper00061007:S.aquatilis_upregulated
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061203:spr-1(ok2144)_upregulated
WBPaper00061340:AIB
WBPaper00061340:AIM
WBPaper00061340:ALM_PLM
WBPaper00061340:DA_DB
WBPaper00061340:hmc
WBPaper00061340:hmc_homolog
WBPaper00061340:mu_int_mu_anal
WBPaper00061340:RIB
WBPaper00061340:RMD
WBPaper00061340:SIA
WBPaper00061340:SMD
WBPaper00061405:S.aureus_downregulated_starvation
WBPaper00061479:hda-1(ne4752)_upregulated
WBPaper00061527:kin-29_2839-unc-9_3883
WBPaper00061527:sol-1-jnk-1_18695
WBPaper00061651:DA9_enriched
WBPaper00061651:DA_enriched
WBPaper00061651:DB_enriched
WBPaper00061651:MC_enriched
WBPaper00061651:URB_enriched
WBPaper00061651:VA12_enriched
WBPaper00061651:VC_4_5_enriched
WBPaper00061902:camt-1(ok515)_regulated_RMG
WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
WBPaper00061995:mter-4(syb3662syb3403)_downregulated
WBPaper00062103:neuron_enriched
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062193:skn-1(RNAi)_downregulated
WBPaper00062325:muscle_enriched_coding-RNA
WBPaper00064071:NHR-49_interacting
WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064306:Agaro-oligosaccharides_upregulated
WBPaper00064716:paraquat_downregulated
WBPaper00064721:fasn-1(g14)_downregulated_starved
WBPaper00064939:vit-5(RNAi)_upregulated
WBPaper00065096:25C_vs_20C_downregulated
WBPaper00065096:Day10_vs_Day1_downregulated
WBPaper00065120:body-muscle-transcriptome
WBPaper00065581:hpk-1(pk1393)_upregulated
WBPaper00065749:Heat-Shock_downregulated_endu-2(tm4977)
WBPaper00065749:Heat-Shock_downregulated_N2
WBPaper00065835:Day5_vs_Day1_downregulated
WBPaper00065841:108_0
WBPaper00065841:118_0
WBPaper00065975:P-body_vs_WholeAnimal_depleted
WBPaper00066110:Cisplatin_upregulated_diploid
WBPaper00066110:tetraploid_vs_diploid_upregulated
cgc4489_group_15
WBPaper00025141:unc-4::GFP_Enriched_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00029437:dcr-1_upregulated
WBPaper00030839:Embryo_A_Class
WBPaper00030839:Embryo_Pan_Neuronal
WBPaper00030839:Larval_A_Class
WBPaper00030839:Larval_Pan_Neuronal
WBPaper00030985:Serratia_marcesens_downregulated
WBPaper00031003:24hr_muscle_enriched
WBPaper00031003:total_muscle_enriched
WBPaper00031252:AIN-1_IP_enriched
WBPaper00031252:AIN-2_IP_enriched
WBPaper00031532:Larva_Pan_Neuronal_Enriched
WBPaper00031832:slr-2_regulated
WBPaper00034661:AgNPs_downregulated
WBPaper00034739:N2moreDR1350
WBPaper00035084:L1_enriched_AIN-2_IP
WBPaper00035588:alg-1(-)_upregulated
WBPaper00036123:Atrazine_regulated
WBPaper00036286:Pattern_C
WBPaper00038304:octr-1_regulated
WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
WBPaper00040876:mir-35_downregulated
WBPaper00040985:AIN-2_asynchronous_muscle
WBPaper00041939:control_vs_UVC-EtBr-exposed_3h
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00041939:EtBr-exposed_vs_UVC-exposed_51h
WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
WBPaper00042274:tbx-2(bx59)_upregulated
WBPaper00042548:miRISC_enriched
WBPaper00045673:colistin_upregulated
WBPaper00048989:N2_rapamycin_upregulated
WBPaper00057098:SiO2-nanoparticles_upregulated
Interaction (65)
Map_infoMapXPosition10.2432Error0.033106
Well_ordered
PositiveInside_rearryDp4
yDp5
yDp6
yDp7
yDp8
yDp9
yDp10
yDp11
yDp12
Positive_cloneR12H7Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_data2_point (15)
Multi_point (65)
Pos_neg_data (29)
Landmark_gene
Reference (101)
MethodGene