WormBase Tree Display for Gene: WBGene00006749
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| WBGene00006749 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | unc-9 | Person_evidence | WBPerson261 | |||||
| Sequence_name | R12H7.1 | ||||||||
| Molecular_name | R12H7.1a | ||||||||
| R12H7.1a.1 | |||||||||
| CE28246 | |||||||||
| R12H7.1b | |||||||||
| CE51729 | |||||||||
| R12H7.1a.2 | |||||||||
| R12H7.1b.1 | |||||||||
| Other_name | CELE_R12H7.1 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | unc-9 | ||||||||
| DB_info | Database | AceView | gene | XN833 | |||||
| WormQTL | gene | WBGene00006749 | |||||||
| WormFlux | gene | WBGene00006749 | |||||||
| NDB | locus_tag | CELE_R12H7.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00006749|UniProtKB=O01393 | |||||||
| family | PTHR11893 | ||||||||
| NCBI | gene | 181443 | |||||||
| RefSeq | protein | NM_001330917.4 | |||||||
| NM_171790.8 | |||||||||
| SwissProt | UniProtAcc | O01393 | |||||||
| TrEMBL | UniProtAcc | A0A1C3NSM1 | |||||||
| UniProt_GCRP | UniProtAcc | O01393 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:41 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | unc | ||||||||
| Reference_allele | WBVar00142960 | ||||||||
| Allele (304) | |||||||||
| Legacy_information | e101 : moves backward better than forward slight kinker in forward movement active healthy; larvae more severely uncoordinated; male fan slightly reduced spicules tend to protrude. ES2 ME0. NA2 (e111). | ||||||||
| [C.elegansII] e101 : moves backward better than forward slight kinker in forward movement active healthy; larvae more severely uncoordinated; suppresses anaesthetic hypersensitivity of unc-79 and unc-80; male fan slightly reduced, spicules tend to protrude. ES2 ME0. OA3: e101, ec27, bx5, e111. Cloned: cosmid rescue (R12H7). [Brenner 1974; Morgan and Sedensky 1994; CW; MQ] | |||||||||
| Strain (29) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (27) | |||||||||
| Ortholog (35) | |||||||||
| Paralog (24) | |||||||||
| Structured_description | Concise_description | unc-9 encodes an innexin, an integral transmembrane channel protein that is a structural component of invertebrate gap junctions; UNC-9 is required for normal forward locomotion and egg-laying and also plays a role in the response to antihelminthics and volatile anesthetics; UNC-9 may form a functional pair with UNC-7, another C. elegans innexin, as mutations in unc-7 result in defects nearly identical to those in unc-9 mutant animals. | Paper_evidence | WBPaper00002950 | |||||
| WBPaper00004670 | |||||||||
| WBPaper00005286 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables actin filament binding activity and gap junction channel activity. Involved in monoatomic ion transmembrane transport and positive regulation of locomotion. Located in gap junction. Expressed in several structures, including anchor cell; muscle cell; neurons; phasmid sheath cell; and somatic nervous system. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | R12H7.1a | |||||||
| R12H7.1b | |||||||||
| Corresponding_CDS_history | R12H7.1:wp52 | ||||||||
| Corresponding_transcript | R12H7.1a.1 | ||||||||
| R12H7.1a.2 | |||||||||
| R12H7.1b.1 | |||||||||
| Other_sequence (38) | |||||||||
| Associated_feature (22) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00089959 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00027706 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00101970 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00090119 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00101969 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00101971 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00051863 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00090277 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00089762 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (11) | |||||||||
| Drives_construct | WBCnstr00005223 | ||||||||
| WBCnstr00011756 | |||||||||
| WBCnstr00012540 | |||||||||
| WBCnstr00013463 | |||||||||
| WBCnstr00016962 | |||||||||
| WBCnstr00018785 | |||||||||
| WBCnstr00019879 | |||||||||
| WBCnstr00034174 | |||||||||
| WBCnstr00042717 | |||||||||
| Construct_product | WBCnstr00004912 | ||||||||
| WBCnstr00007077 | |||||||||
| WBCnstr00014822 | |||||||||
| WBCnstr00017891 | |||||||||
| WBCnstr00018129 | |||||||||
| WBCnstr00019880 | |||||||||
| WBCnstr00021094 | |||||||||
| WBCnstr00022772 | |||||||||
| WBCnstr00022774 | |||||||||
| WBCnstr00034174 | |||||||||
| Antibody | WBAntibody00001277 | ||||||||
| WBAntibody00001907 | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (186) | |||||||||
| Interaction | WBInteraction000000034 | ||||||||
| WBInteraction000000548 | |||||||||
| WBInteraction000000549 | |||||||||
| WBInteraction000002500 | |||||||||
| WBInteraction000002502 | |||||||||
| WBInteraction000005402 | |||||||||
| WBInteraction000005403 | |||||||||
| WBInteraction000005404 | |||||||||
| WBInteraction000029653 | |||||||||
| WBInteraction000031793 | |||||||||
| WBInteraction000031885 | |||||||||
| WBInteraction000039552 | |||||||||
| WBInteraction000052190 | |||||||||
| WBInteraction000052191 | |||||||||
| WBInteraction000052195 | |||||||||
| WBInteraction000052200 | |||||||||
| WBInteraction000052211 | |||||||||
| WBInteraction000052268 | |||||||||
| WBInteraction000052321 | |||||||||
| WBInteraction000052323 | |||||||||
| WBInteraction000052325 | |||||||||
| WBInteraction000126283 | |||||||||
| WBInteraction000126284 | |||||||||
| WBInteraction000126342 | |||||||||
| WBInteraction000126478 | |||||||||
| WBInteraction000126479 | |||||||||
| WBInteraction000126547 | |||||||||
| WBInteraction000126921 | |||||||||
| WBInteraction000127402 | |||||||||
| WBInteraction000135202 | |||||||||
| WBInteraction000153249 | |||||||||
| WBInteraction000166391 | |||||||||
| WBInteraction000180443 | |||||||||
| WBInteraction000180840 | |||||||||
| WBInteraction000195374 | |||||||||
| WBInteraction000195375 | |||||||||
| WBInteraction000195378 | |||||||||
| WBInteraction000195379 | |||||||||
| WBInteraction000222906 | |||||||||
| WBInteraction000299198 | |||||||||
| WBInteraction000366660 | |||||||||
| WBInteraction000387318 | |||||||||
| WBInteraction000437085 | |||||||||
| WBInteraction000456312 | |||||||||
| WBInteraction000469049 | |||||||||
| WBInteraction000471484 | |||||||||
| WBInteraction000502986 | |||||||||
| WBInteraction000518927 | |||||||||
| WBInteraction000518931 | |||||||||
| WBInteraction000535487 | |||||||||
| WBInteraction000535488 | |||||||||
| WBInteraction000535489 | |||||||||
| WBInteraction000535490 | |||||||||
| WBInteraction000535498 | |||||||||
| WBInteraction000535499 | |||||||||
| WBInteraction000541464 | |||||||||
| WBInteraction000554751 | |||||||||
| WBInteraction000554753 | |||||||||
| WBInteraction000556777 | |||||||||
| WBInteraction000556779 | |||||||||
| WBInteraction000561573 | |||||||||
| WBInteraction000561574 | |||||||||
| WBInteraction000569811 | |||||||||
| WBInteraction000569812 | |||||||||
| WBInteraction000576895 | |||||||||
| Map_info | Map | X | Position | 10.2432 | Error | 0.033106 | |||
| Well_ordered | |||||||||
| Positive (2) | |||||||||
| Mapping_data | 2_point (15) | ||||||||
| Multi_point (65) | |||||||||
| Pos_neg_data (29) | |||||||||
| Landmark_gene | |||||||||
| Reference (101) | |||||||||
| Method | Gene |
