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WormBase Tree Display for Gene: WBGene00006762

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Name Class

WBGene00006762SMapS_parentSequenceY37D8A
IdentityVersion1
NameCGC_nameunc-25Person_evidenceWBPerson261
Sequence_nameY37D8A.23
Molecular_nameY37D8A.23a
Y37D8A.23a.1
CE20226
Y37D8A.23b
CE31832
Y37D8A.23c
CE32012
Y37D8A.23b.1
Y37D8A.23c.1
Other_nameCELE_Y37D8A.23Accession_evidenceNDBBX284603
Public_nameunc-25
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:42WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_info (12)
Disease_infoExperimental_modelDOID:1574Homo sapiensPaper_evidenceWBPaper00045914
Curator_confirmedWBPerson324
Date_last_updated06 Jun 2019 00:00:00
DOID:1826Homo sapiensPaper_evidenceWBPaper00035198
Curator_confirmedWBPerson38202
Date_last_updated04 Jun 2018 00:00:00
DOID:0050669Homo sapiensPaper_evidenceWBPaper00024523
Accession_evidenceOMIM603513
Curator_confirmedWBPerson324
Date_last_updated22 Apr 2013 00:00:00
Potential_model (12)
Disease_relevanceMutations in Glutamic acid decarboxylase (GAD1), the human ortholog of elegans unc-25, are associated with autosomal recessive spastic cerebral palsy, a movement disorder caused by abnormalities in the brain; studies in elegans show that unc-25 is required for gamma-amino-butyric acid (GABA) synthesis and GABA-mediated behavioral functions; various GABA mutants in elegans, like unc-25, the GABA vesicular transporters (unc-46 and unc-47), and the GABA-A receptor, unc-49, all present head-bobbing convulsions.Homo sapiensPaper_evidenceWBPaper00024523
WBPaper00042136
Accession_evidenceOMIM603513
605363
Curator_confirmedWBPerson324
Date_last_updated22 Apr 2013 00:00:00
Models_disease_in_annotationWBDOannot00000163
Models_disease_assertedWBDOannot00000549
WBDOannot00000702
WBDOannot00000703
Molecular_infoCorresponding_CDSY37D8A.23a
Y37D8A.23b
Y37D8A.23c
Corresponding_transcriptY37D8A.23a.1
Y37D8A.23b.1
Y37D8A.23c.1
Other_sequence (65)
Associated_featureWBsf645681
WBsf994764
WBsf994765
WBsf1016280
WBsf1016281
WBsf1016282
WBsf225951
WBsf225952
Experimental_infoRNAi_resultWBRNAi00090105Inferred_automaticallyRNAi_primary
WBRNAi00077589Inferred_automaticallyRNAi_primary
WBRNAi00077586Inferred_automaticallyRNAi_primary
WBRNAi00027872Inferred_automaticallyRNAi_primary
WBRNAi00089945Inferred_automaticallyRNAi_primary
WBRNAi00002293Inferred_automaticallyRNAi_primary
WBRNAi00055883Inferred_automaticallyRNAi_primary
WBRNAi00090263Inferred_automaticallyRNAi_primary
WBRNAi00089782Inferred_automaticallyRNAi_primary
Expr_pattern (15)
Drives_constructWBCnstr00000605
WBCnstr00000609
WBCnstr00000703
WBCnstr00000704
WBCnstr00000705
WBCnstr00000714
WBCnstr00000715
WBCnstr00000716
WBCnstr00000717
WBCnstr00000719
WBCnstr00000720
WBCnstr00000721
WBCnstr00000743
WBCnstr00000744
WBCnstr00000745
WBCnstr00001267
WBCnstr00001359
WBCnstr00004773
WBCnstr00004999
WBCnstr00005433
WBCnstr00005435
WBCnstr00005477
WBCnstr00005556
WBCnstr00005598
WBCnstr00005854
WBCnstr00005942
WBCnstr00005943
WBCnstr00005944
WBCnstr00006323
WBCnstr00006403
WBCnstr00006404
WBCnstr00006409
WBCnstr00006410
WBCnstr00006413
WBCnstr00006423
WBCnstr00006819
WBCnstr00007003
WBCnstr00007363
WBCnstr00007364
WBCnstr00007368
WBCnstr00007378
WBCnstr00007410
WBCnstr00007411
WBCnstr00007412
WBCnstr00007413
WBCnstr00007416
WBCnstr00007425
WBCnstr00008269
WBCnstr00008278
WBCnstr00008281
WBCnstr00008800
WBCnstr00008802
WBCnstr00008803
WBCnstr00008804
WBCnstr00008818
WBCnstr00008877
WBCnstr00008999
WBCnstr00009000
WBCnstr00009001
WBCnstr00009004
WBCnstr00009114
WBCnstr00009115
WBCnstr00009264
WBCnstr00009288
WBCnstr00009289
WBCnstr00009689
WBCnstr00009758
WBCnstr00009980
WBCnstr00010110
WBCnstr00010150
WBCnstr00010179
WBCnstr00010753
WBCnstr00013575
WBCnstr00014467
WBCnstr00014779
WBCnstr00014793
WBCnstr00015841
WBCnstr00018448
WBCnstr00018450
WBCnstr00018451
WBCnstr00018452
WBCnstr00018453
WBCnstr00018454
WBCnstr00018455
WBCnstr00018490
WBCnstr00018491
WBCnstr00018689
WBCnstr00018712
WBCnstr00018847
WBCnstr00019391
WBCnstr00019469
WBCnstr00019589
WBCnstr00019873
WBCnstr00019874
WBCnstr00019976
WBCnstr00020332
WBCnstr00020608
WBCnstr00020698
WBCnstr00020968
WBCnstr00021237
WBCnstr00021679
WBCnstr00022487
WBCnstr00022488
WBCnstr00022691
WBCnstr00022693
WBCnstr00022694
WBCnstr00022695
WBCnstr00022696
WBCnstr00022697
WBCnstr00022699
WBCnstr00022700
WBCnstr00022938
WBCnstr00022986
WBCnstr00023004
WBCnstr00023027
WBCnstr00023028
WBCnstr00038194
WBCnstr00038220
WBCnstr00038223
WBCnstr00038744
WBCnstr00038745
WBCnstr00039443
WBCnstr00039978
WBCnstr00039999
WBCnstr00040714
WBCnstr00041553
WBCnstr00041568
WBCnstr00041569
WBCnstr00041735
WBCnstr00042175
WBCnstr00042627
WBCnstr00042632
WBCnstr00042713
WBCnstr00042783
WBCnstr00042922
WBCnstr00043032
Construct_productWBCnstr00010179
WBCnstr00038179
WBCnstr00038181
Regulate_expr_clusterWBPaper00065734:unc-25(e156)_downregulated
WBPaper00065734:unc-25(e156)_upregulated
Microarray_results (30)
Expression_cluster (186)
Interaction (55)
WBProcessWBbiopr:00000010
Map_infoMapIIIPosition20.6616Error0.04207
Well_ordered
PositivePositive_cloneY37D8AInferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_data2_point57
68
78
6019
6109
7009
7010
Multi_point (42)
Pos_neg_data354
8378
8386
8389
8550
Reference (216)
MethodGene