WormBase Tree Display for Gene: WBGene00006801

WBGene00006801 SMap: S_parent: Sequence: CHROMOSOME_V
  Identity: Version: 2
    Name: CGC_name: unc-68 Person_evidence: WBPerson261
      Sequence_name: K11C4.5
      Molecular_name (48)
      Other_name: ryr-1
        kra-1
        CELE_K11C4.5 Accession_evidence: NDB BX284605
      Public_name: unc-68
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:43 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 07 Nov 2007 17:12:59 WBPerson2970 Event: Acquires_merge: WBGene00021962
      Acquires_merge: WBGene00021962
    Status: Live
  Gene_info (12)
  Disease_info: Experimental_model: DOID:3529 Homo sapiens Paper_evidence: WBPaper00059411
          Curator_confirmed: WBPerson324
          Date_last_updated: 08 Jun 2021 00:00:00
      DOID:8545 Homo sapiens Paper_evidence: WBPaper00059411
          Curator_confirmed: WBPerson324
          Date_last_updated: 08 Jun 2021 00:00:00
    Potential_model (12)
  Modifies_disease: DOID:11723
  Modifies_disease_in_annotation: WBDOannot00000746
  Models_disease_asserted (14)
  Molecular_info: Corresponding_CDS (16)
    Corresponding_CDS_history: K11C4.5:wp166
      K11C4.5:wp184
      K11C4.5a:wp261
      K11C4.5b:wp236
      K11C4.5b:wp261
      K11C4.5c:wp261
      K11C4.5d:wp261
    Corresponding_transcript (16)
    Other_sequence (63)
    Associated_feature (24)
  Experimental_info: RNAi_result (20)
    Expr_pattern (12)
    Drives_construct: WBCnstr00006689
      WBCnstr00010174
      WBCnstr00010354
      WBCnstr00010749
      WBCnstr00015983
      WBCnstr00015984
      WBCnstr00039937
      WBCnstr00039938
    Construct_product: WBCnstr00000351
      WBCnstr00000352
      WBCnstr00006689
      WBCnstr00010354
      WBCnstr00010749
      WBCnstr00014791
      WBCnstr00016961
      WBCnstr00017064
    Antibody (12)
    Microarray_results (34)
    Expression_cluster: WBPaper00005700:transmembrane_protein
      WBPaper00031040:Cluster_1
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00033065:isp-1-1(qm150)_upregulated
      WBPaper00035269:cde-1_regulated
      WBPaper00036291:ung-1_regulated
      WBPaper00037055:DAF-16_binding_DNA
      WBPaper00038168:lin-15B(n744)_upregulated
      WBPaper00038289:oocyte_protein
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_downregulated_TilingArray
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044316:HgCl2_20uM_downregulated
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044736:flat_dev_expression
      WBPaper00045417:128Q-huntingtin_upreglated
      WBPaper00045521:Spermatogenic
      WBPaper00046121:mesoderm_unique
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046805:csr-1(RNAi)_downregulated_Set1
      WBPaper00046805:csr-1(RNAi)_downregulated_Set2
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049498:npr-1(ur89)_regulated_3
      WBPaper00049942:HeatShock_upregulated_hsf-1(RNAi)
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050182:lmn-1(L535P)_upregulated
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_20C
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:ash-2(RNAi)_regulated_intestine
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053321:embryo-to-L1_downregulated_WT_SMARTseq
      WBPaper00053321:PGCs_depleted_NuGen
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00054493:hpl-2(tm1489)_upregulated
      WBPaper00055334:DLC-1_interacting
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055354:Rapamycin-Rifampicin_upregulated
      WBPaper00055354:Rifampicin-Psora_upregulated
      WBPaper00055354:Rifampicin_upregulated
      WBPaper00055482:pmt-2(RNAi)_downregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055969:electromagnetic-field_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056826:hmc_biased
      WBPaper00056855:his-72(uge40)_downregulated
      WBPaper00057154:HeatShock_upregulated_mRNA
      WBPaper00057162:meg-3_meg-4_downregulated_sRNA
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00059471:EGL-43_interacting
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059895:wounding_downregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060014:set-2(zr2012)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060459:bcat-1(RNAi)_upregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061210:huIs179_upregulated
      WBPaper00061340:BWM_anterior
      WBPaper00061340:BWM_far_posterior
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061527:172183_at-176110_at
      WBPaper00061527:myo-3-Y71G12B.11_22540
      WBPaper00061527:tnt-4-myo-1_2160
      WBPaper00061651:BDU_enriched
      WBPaper00061651:DA_enriched
      WBPaper00061651:I3_enriched
      WBPaper00061651:LUA_enriched
      WBPaper00061651:PVD_enriched
      WBPaper00061651:PVR_enriched
      WBPaper00061753:csr-1(tor159)_downregulated_20C
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00062103:neuron_enriched
      WBPaper00062156:jmjd-5(zr1234)_upregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062293:isp-1(qm150)_upregulated
      WBPaper00062325:etr-1(lq61)_downregulated
      WBPaper00062325:etr-1(lq61)_upregulated
      WBPaper00064071:NHR-49_interacting
      WBPaper00064080:miR-2_miRNA_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064122:vulva_transcriptome
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064728:cpl-1(W32AY35A)_upregulated
      WBPaper00064735:bet-1B(OE)mys-1(RNAi)_vs_mys-1(RNAi)_downregulated
      WBPaper00064735:mys-1(RNAi)_vs_N2_upregulated
      WBPaper00064939:vit-5(RNAi)_upregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065149:lin-52(n771)_downregulated
      WBPaper00065158:AFD_enriched
      WBPaper00065225:nhr-42(tm1375)_upregulated_S.aureus-infected
      WBPaper00065373:sek-1(km4)_downregulated_cisplatin
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065623:97
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065841:4_0
      WBPaper00065841:7_0
      WBPaper00065841:7_1
      WBPaper00065841:38_2
      WBPaper00065841:70_1
      WBPaper00065841:80_0
      WBPaper00065841:108_0
      WBPaper00065841:143_0
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4386_cluster_6_6
      cgc4489_group_14
      cgc4489_group_20
      cgc4489_male_enriched_neuronal_genes
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Enriched_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00027111:rrf-2(ok210)_upregulated
      WBPaper00030839:Embryo_A_Class
      WBPaper00030839:Embryo_Pan_Neuronal
      WBPaper00031003:0hr_muscle_enriched
      WBPaper00031003:24hr_muscle_enriched
      WBPaper00031003:hlh_1_enriched
      WBPaper00031003:total_muscle_enriched
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00031832:slr-2_regulated
      WBPaper00034661:AgNPs_downregulated
      WBPaper00035084:L3_enriched_AIN-2_IP
      WBPaper00035084:L4_enriched_AIN-2_IP
      WBPaper00035560:ahr-1_upregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036286:Pattern_C
      WBPaper00036375:depleted_in_PVD_OLL
      WBPaper00037113:Diazinon_16C_regulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.5
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040823:alg-1(gk214)_downregulated
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040858:eQTL_regulated_old
      WBPaper00040858:eQTL_regulated_reproductive
      WBPaper00040963:TA200_down
      WBPaper00040963:TA300_down
      WBPaper00040985:AIN-2_asynchronous_muscle
      WBPaper00041002:HQ_3d_2.0mM_Down
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_3h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
      WBPaper00042331:a-SWCNTs_downregulated
      WBPaper00045263:0.1mM-paraquat_downregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00045673:colistin_upregulated
      WBPaper00047070:xpa-1_UV_downregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00048989:N2_allantoin_upregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00049311:AgNO3_regulated
      WBPaper00049311:sAg-MNP_regulated
      WBPaper00050650:mBmkTX_downregulated
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
      [cgc6390]:Cluster_C
    Interaction (56)
  Map_info: Map: V Position: 0.477486 Error: 0.002969
    Well_ordered
    Positive: Inside_rearr: sDf20
      Positive_clone: K11C4 Inferred_automatically: From sequence, transcript, pseudogene data
        M04C11
    Negative: Outside_rearr: nDf31
      Negative_clone: M04C11
    Mapping_data: 2_point: 310
        2841
        3136
        4524
      Multi_point (17)
      Pos_neg_data (16)
    Landmark_gene
  Reference (150)
  Remark: results of mutation site, phenotype, rescue appear in J. Mol. Biol. 267, 849-864. 1997 Sakube, Y., Ando, H. & Kagawa H.
  Method: Gene