WormBase Tree Display for Gene: WBGene00006801

WBGene00006801 SMap: S_parent: Sequence: CHROMOSOME_V
  Identity: Version: 2
    Name: CGC_name: unc-68 Person_evidence: WBPerson261
      Sequence_name: K11C4.5
      Molecular_name (48)
      Other_name: ryr-1
        kra-1
        CELE_K11C4.5 Accession_evidence: NDB BX284605
      Public_name: unc-68
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:43 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 07 Nov 2007 17:12:59 WBPerson2970 Event: Acquires_merge: WBGene00021962
      Acquires_merge: WBGene00021962
    Status: Live
  Gene_info (12)
  Disease_info: Experimental_model: DOID:3529 Homo sapiens Paper_evidence: WBPaper00059411
          Curator_confirmed: WBPerson324
          Date_last_updated: 08 Jun 2021 00:00:00
      DOID:8545 Homo sapiens Paper_evidence: WBPaper00059411
          Curator_confirmed: WBPerson324
          Date_last_updated: 08 Jun 2021 00:00:00
    Potential_model (12)
  Modifies_disease: DOID:11723
  Modifies_disease_in_annotation: WBDOannot00000746
  Models_disease_asserted (14)
  Molecular_info: Corresponding_CDS (16)
    Corresponding_CDS_history: K11C4.5:wp166
      K11C4.5:wp184
      K11C4.5a:wp261
      K11C4.5b:wp236
      K11C4.5b:wp261
      K11C4.5c:wp261
      K11C4.5d:wp261
    Corresponding_transcript (16)
    Other_sequence (63)
    Associated_feature (24)
  Experimental_info: RNAi_result (20)
    Expr_pattern (12)
    Drives_construct: WBCnstr00006689
      WBCnstr00010174
      WBCnstr00010354
      WBCnstr00010749
      WBCnstr00015983
      WBCnstr00015984
      WBCnstr00039937
      WBCnstr00039938
    Construct_product: WBCnstr00000351
      WBCnstr00000352
      WBCnstr00006689
      WBCnstr00010354
      WBCnstr00010749
      WBCnstr00014791
      WBCnstr00016961
      WBCnstr00017064
    Antibody (12)
    Microarray_results (34)
    Expression_cluster: WBPaper00005700:transmembrane_protein
      WBPaper00031040:Cluster_1
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00033065:isp-1-1(qm150)_upregulated
      WBPaper00035269:cde-1_regulated
      WBPaper00036291:ung-1_regulated
      WBPaper00037055:DAF-16_binding_DNA
      WBPaper00038168:lin-15B(n744)_upregulated
      WBPaper00038289:oocyte_protein
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_downregulated_TilingArray
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044316:HgCl2_20uM_downregulated
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044736:flat_dev_expression
      WBPaper00045417:128Q-huntingtin_upreglated
      WBPaper00045521:Spermatogenic
      WBPaper00046121:mesoderm_unique
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046805:csr-1(RNAi)_downregulated_Set1
      WBPaper00046805:csr-1(RNAi)_downregulated_Set2
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049498:npr-1(ur89)_regulated_3
      WBPaper00049942:HeatShock_upregulated_hsf-1(RNAi)
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050182:lmn-1(L535P)_upregulated
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_20C
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:ash-2(RNAi)_regulated_intestine
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053321:embryo-to-L1_downregulated_WT_SMARTseq
      WBPaper00053321:PGCs_depleted_NuGen
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00054493:hpl-2(tm1489)_upregulated
      WBPaper00055334:DLC-1_interacting
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055354:Rapamycin-Rifampicin_upregulated
      WBPaper00055354:Rifampicin-Psora_upregulated
      WBPaper00055354:Rifampicin_upregulated
      WBPaper00055482:pmt-2(RNAi)_downregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055969:electromagnetic-field_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056826:hmc_biased
      WBPaper00056855:his-72(uge40)_downregulated
      WBPaper00057154:HeatShock_upregulated_mRNA
      WBPaper00057162:meg-3_meg-4_downregulated_sRNA
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00059471:EGL-43_interacting
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059895:wounding_downregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060014:set-2(zr2012)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060459:bcat-1(RNAi)_upregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061210:huIs179_upregulated
      WBPaper00061340:BWM_anterior
      WBPaper00061340:BWM_far_posterior
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061527:172183_at-176110_at
      WBPaper00061527:myo-3-Y71G12B.11_22540
      WBPaper00061527:tnt-4-myo-1_2160
      WBPaper00061651:BDU_enriched
      WBPaper00061651:DA_enriched
      WBPaper00061651:I3_enriched
      WBPaper00061651:LUA_enriched
      WBPaper00061651:PVD_enriched
      WBPaper00061651:PVR_enriched
      WBPaper00061753:csr-1(tor159)_downregulated_20C
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00062103:neuron_enriched
      WBPaper00062156:jmjd-5(zr1234)_upregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062293:isp-1(qm150)_upregulated
      WBPaper00062325:etr-1(lq61)_downregulated
      WBPaper00062325:etr-1(lq61)_upregulated
      WBPaper00064071:NHR-49_interacting
      WBPaper00064080:miR-2_miRNA_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064122:vulva_transcriptome
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064728:cpl-1(W32AY35A)_upregulated
      WBPaper00064735:bet-1B(OE)mys-1(RNAi)_vs_mys-1(RNAi)_downregulated
      WBPaper00064735:mys-1(RNAi)_vs_N2_upregulated
      WBPaper00064939:vit-5(RNAi)_upregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065149:lin-52(n771)_downregulated
      WBPaper00065158:AFD_enriched
      WBPaper00065225:nhr-42(tm1375)_upregulated_S.aureus-infected
      WBPaper00065373:sek-1(km4)_downregulated_cisplatin
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065623:97
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065841:4_0
      WBPaper00065841:7_0
      WBPaper00065841:7_1
      WBPaper00065841:38_2
      WBPaper00065841:70_1
      WBPaper00065841:80_0
      WBPaper00065841:108_0
      WBPaper00065841:143_0
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4386_cluster_6_6
      cgc4489_group_14
      cgc4489_group_20
      cgc4489_male_enriched_neuronal_genes
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Enriched_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00027111:rrf-2(ok210)_upregulated
      WBPaper00030839:Embryo_A_Class
      WBPaper00030839:Embryo_Pan_Neuronal
      WBPaper00031003:0hr_muscle_enriched
      WBPaper00031003:24hr_muscle_enriched
      WBPaper00031003:hlh_1_enriched
      WBPaper00031003:total_muscle_enriched
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00031832:slr-2_regulated
      WBPaper00034661:AgNPs_downregulated
      WBPaper00035084:L3_enriched_AIN-2_IP
      WBPaper00035084:L4_enriched_AIN-2_IP
      WBPaper00035560:ahr-1_upregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036286:Pattern_C
      WBPaper00036375:depleted_in_PVD_OLL
      WBPaper00037113:Diazinon_16C_regulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.5
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040823:alg-1(gk214)_downregulated
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040858:eQTL_regulated_old
      WBPaper00040858:eQTL_regulated_reproductive
      WBPaper00040963:TA200_down
      WBPaper00040963:TA300_down
      WBPaper00040985:AIN-2_asynchronous_muscle
      WBPaper00041002:HQ_3d_2.0mM_Down
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_3h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
      WBPaper00042331:a-SWCNTs_downregulated
      WBPaper00045263:0.1mM-paraquat_downregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00045673:colistin_upregulated
      WBPaper00047070:xpa-1_UV_downregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00048989:N2_allantoin_upregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00049311:AgNO3_regulated
      WBPaper00049311:sAg-MNP_regulated
      WBPaper00050650:mBmkTX_downregulated
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
      [cgc6390]:Cluster_C
    Interaction (56)
  Map_info: Map: V Position: 0.477486 Error: 0.002969
    Well_ordered
    Positive: Inside_rearr: sDf20
      Positive_clone: K11C4 Inferred_automatically: From sequence, transcript, pseudogene data
        M04C11
    Negative: Outside_rearr: nDf31
      Negative_clone: M04C11
    Mapping_data: 2_point: 310
        2841
        3136
        4524
      Multi_point (17)
      Pos_neg_data (16)
    Landmark_gene
  Reference: WBPaper00000031
    WBPaper00000320
    WBPaper00000464
    WBPaper00000484
    WBPaper00000608
    WBPaper00000622
    WBPaper00000998
    WBPaper00001474
    WBPaper00001576
    WBPaper00001928
    WBPaper00002194
    WBPaper00002536
    WBPaper00002748
    WBPaper00002749
    WBPaper00003239
    WBPaper00003300
    WBPaper00004468
    WBPaper00004880
    WBPaper00004883
    WBPaper00005595
    WBPaper00005617
    WBPaper00005753
    WBPaper00005799
    WBPaper00006076
    WBPaper00006125
    WBPaper00006193
    WBPaper00006402
    WBPaper00010563
    WBPaper00010763
    WBPaper00011264
    WBPaper00011791
    WBPaper00011909
    WBPaper00011910
    WBPaper00011949
    WBPaper00011995
    WBPaper00013423
    WBPaper00014047
    WBPaper00014136
    WBPaper00014150
    WBPaper00014153
    WBPaper00014466
    WBPaper00014634
    WBPaper00014725
    WBPaper00014854
    WBPaper00015030
    WBPaper00015031
    WBPaper00015116
    WBPaper00015273
    WBPaper00015313
    WBPaper00015367
    WBPaper00015440
    WBPaper00015497
    WBPaper00015529
    WBPaper00015780
    WBPaper00016386
    WBPaper00016990
    WBPaper00017307
    WBPaper00017365
    WBPaper00017693
    WBPaper00017842
    WBPaper00018462
    WBPaper00018465
    WBPaper00018605
    WBPaper00018906
    WBPaper00019424
    WBPaper00021054
    WBPaper00022031
    WBPaper00022183
    WBPaper00022339
    WBPaper00022529
    WBPaper00022677
    WBPaper00022940
    WBPaper00023194
    WBPaper00023206
    WBPaper00023257
    WBPaper00023418
    WBPaper00023603
    WBPaper00024250
    WBPaper00025376
    WBPaper00026084
    WBPaper00026249
    WBPaper00026310
    WBPaper00026649
    WBPaper00026667
    WBPaper00026679
    WBPaper00026830
    WBPaper00026988
    WBPaper00027304
    WBPaper00027624
    WBPaper00027747
    WBPaper00028127
    WBPaper00028850
    WBPaper00029025
    WBPaper00029029
    WBPaper00029239
    WBPaper00030941
    WBPaper00030977
    WBPaper00031000
    WBPaper00031025
    WBPaper00031105
    WBPaper00031671
    WBPaper00035989
    WBPaper00036072
    WBPaper00038491
    WBPaper00038921
    WBPaper00039197
    WBPaper00039287
    WBPaper00040284
    WBPaper00041560
    WBPaper00042434
    WBPaper00042470
    WBPaper00042761
    WBPaper00042830
    WBPaper00043309
    WBPaper00043689
    WBPaper00043908
    WBPaper00046054
    WBPaper00048069
    WBPaper00049318
    WBPaper00050014
    WBPaper00050936
    WBPaper00051300
    WBPaper00051610
    WBPaper00051697
    WBPaper00051845
    WBPaper00052356
    WBPaper00052403
    WBPaper00052743
    WBPaper00053461
    WBPaper00055090
    WBPaper00055814
    WBPaper00056839
    WBPaper00057557
    WBPaper00057563
    WBPaper00057691
    WBPaper00057827
    WBPaper00058512
    WBPaper00059037
    WBPaper00059411
    WBPaper00059791
    WBPaper00060523
    WBPaper00060661
    WBPaper00061245
    WBPaper00061313
    WBPaper00063935
    WBPaper00064788
    WBPaper00064902
    WBPaper00065040
    WBPaper00065135
    WBPaper00065585
  Remark: results of mutation site, phenotype, rescue appear in J. Mol. Biol. 267, 849-864. 1997 Sakube, Y., Ando, H. & Kagawa H.
  Method: Gene