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WormBase Tree Display for Gene: WBGene00006808

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Name Class

WBGene00006808SMapS_parentSequenceC01G10
IdentityVersion1
NameCGC_nameunc-76Person_evidenceWBPerson261
Sequence_nameC01G10.11
Molecular_name (18)
Other_nameCELE_C01G10.11Accession_evidenceNDBBX284605
Public_nameunc-76
DB_infoDatabaseAceViewgene5P559
WormQTLgeneWBGene00006808
WormFluxgeneWBGene00006808
NDBlocus_tagCELE_C01G10.11
PanthergeneCAEEL|WormBase=WBGene00006808|UniProtKB=E0AHC6
familyPTHR12394
NCBIgene180014
RefSeqproteinNM_001269717.3
NM_001269716.3
NM_001269719.3
NM_001269718.3
NM_074311.7
NM_171553.6
TREEFAMTREEFAM_IDTF313128
TrEMBLUniProtAccE0AHC6
E0AHC4
E0AHC3
E0AHC5
Q7JL61
Q7JL62
UniProt_GCRPUniProtAccE0AHC6
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:43WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classunc
Reference_alleleWBVar00143591
Allele (163)
Legacy_informatione911pdi : inactive tends to curl dumpyish; Egl-c; amphid phasmid PDE axons abnormal; dorsal extensions of DD and VD neurons frequently grow in abnormal directions often fail to connect to dorsal nerve cord. ES3 ME0. NA1.
[C.elegansII] e911pdi : inactive, tends to curl, dumpyish; Egl-c; amphid, phasmid, PDE, PVP, other axons abnormal; dorsal extensions of DD and VD neurons frequently grow in abnormal directions, often fail to connect to dorsal nervecord. Defects in axonal elongation and fasciculation along nerve cords. ES3 ME0. NA1. Cloned: 1.8 kb transcripts, encode predicted 385 or 376 aa novel proteins. Epitope-tagged UNC-76 detected in axons. [Hedgecock et al. 1985; McIntire et al. 1992; MT]
StrainWBStrain00022737
WBStrain00022738
WBStrain00026576
WBStrain00027000
WBStrain00027071
WBStrain00027209
WBStrain00027248
WBStrain00027249
WBStrain00027258
WBStrain00027273
WBStrain00027369
WBStrain00027374
WBStrain00027383
WBStrain00028842
WBStrain00029116
WBStrain00029186
WBStrain00029552
WBStrain00034370
WBStrain00034440
WBStrain00035101
WBStrain00035102
WBStrain00035103
WBStrain00035104
WBStrain00035106
WBStrain00035110
WBStrain00040214
WBStrain00000373
WBStrain00000826
WBStrain00003933
WBStrain00004367
WBStrain00005195
WBStrain00005198
WBStrain00005199
WBStrain00005507
WBStrain00005521
WBStrain00006215
WBStrain00006180
WBStrain00007143
WBStrain00008485
WBStrain00008487
WBStrain00008488
WBStrain00008489
WBStrain00008492
WBStrain00008493
WBStrain00008504
WBStrain00008505
WBStrain00008469
WBStrain00008470
WBStrain00008482
WBStrain00008606
WBStrain00047716
WBStrain00047717
WBStrain00051503
WBStrain00051502
RNASeq_FPKM (74)
GO_annotation (22)
Ortholog (39)
Structured_descriptionConcise_descriptionunc-76 encodes a predicted coiled-coil protein that belongs to the FEZ (fasciculation and elongation protein; zygin/zeta-1) family of proteins; UNC-76 activity is required for normal axonal outgrowth and fasciculation and hence, normal locomotion; UNC-76 expression begins during embryogenesis and is present in all axons throughout development; UNC-76 localizes to both axons and cell bodies.Paper_evidenceWBPaper00002751
Curator_confirmedWBPerson1843
Date_last_updated31 May 2006 00:00:00
Automated_descriptionEnables syntaxin binding activity. Involved in anterograde axonal protein transport; axonal fasciculation; and regulation of cellular component organization. Located in axon; neuronal cell body; and perinuclear region of cytoplasm. Expressed in neurons and somatic nervous system. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human FEZ1 (fasciculation and elongation protein zeta 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:5419Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3659)
Molecular_infoCorresponding_CDSC01G10.11a
C01G10.11b
C01G10.11c
C01G10.11d
C01G10.11e
C01G10.11f
Corresponding_CDS_historyC01G10.11a:wp151
C01G10.11b:wp151
Corresponding_transcriptC01G10.11a.1
C01G10.11b.1
C01G10.11c.1
C01G10.11d.1
C01G10.11e.1
C01G10.11f.1
Other_sequence (20)
Associated_feature (21)
Experimental_infoRNAi_resultWBRNAi00089749Inferred_automaticallyRNAi_primary
WBRNAi00027631Inferred_automaticallyRNAi_primary
WBRNAi00009926Inferred_automaticallyRNAi_primary
WBRNAi00089948Inferred_automaticallyRNAi_primary
WBRNAi00039322Inferred_automaticallyRNAi_primary
WBRNAi00086127Inferred_automaticallyRNAi_primary
WBRNAi00090266Inferred_automaticallyRNAi_primary
WBRNAi00090108Inferred_automaticallyRNAi_primary
Expr_patternExpr1621
Expr1019687
Expr1032875
Expr1143433
Expr2017905
Expr2036041
Drives_constructWBCnstr00001401
WBCnstr00034141
Construct_product (15)
AntibodyWBAntibody00000143
Microarray_results (40)
Expression_cluster (180)
Interaction (37)
Map_infoMapVPosition7.32052Error0.012665
Well_ordered
PositivePositive_cloneC01G10Inferred_automaticallyFrom sequence, transcript, pseudogene data
C08C1Inferred_automaticallyFrom sequence, transcript, pseudogene data
NegativeOutside_rearrnDf31
ozDf1
Mapping_data2_point (15)
Multi_point (103)
Pos_neg_data4288
4289
4290
4304
8977
Landmark_gene
ReferenceWBPaper00000031
WBPaper00000608
WBPaper00000793
WBPaper00000916
WBPaper00000978
WBPaper00001105
WBPaper00001255
WBPaper00001296
WBPaper00001345
WBPaper00001435
WBPaper00001499
WBPaper00001508
WBPaper00001679
WBPaper00001688
WBPaper00001691
WBPaper00001692
WBPaper00001704
WBPaper00001709
WBPaper00001719
WBPaper00001826
WBPaper00001854
WBPaper00002003
WBPaper00002403
WBPaper00002751
WBPaper00003509
WBPaper00003665
WBPaper00003760
WBPaper00004362
WBPaper00004561
WBPaper00004883
WBPaper00005236
WBPaper00005423
WBPaper00005719
WBPaper00006025
WBPaper00006052
WBPaper00006072
WBPaper00006103
WBPaper00006497
WBPaper00010128
WBPaper00010210
WBPaper00010331
WBPaper00010591
WBPaper00011058
WBPaper00011907
WBPaper00012655
WBPaper00012741
WBPaper00013779
WBPaper00013781
WBPaper00013783
WBPaper00013790
WBPaper00013845
WBPaper00013900
WBPaper00014003
WBPaper00014180
WBPaper00014206
WBPaper00014220
WBPaper00014236
WBPaper00014321
WBPaper00014346
WBPaper00014421
WBPaper00014652
WBPaper00014687
WBPaper00014712
WBPaper00014733
WBPaper00015091
WBPaper00015104
WBPaper00015176
WBPaper00015184
WBPaper00015355
WBPaper00015403
WBPaper00015440
WBPaper00015579
WBPaper00015698
WBPaper00015974
WBPaper00016076
WBPaper00016121
WBPaper00016259
WBPaper00016260
WBPaper00016267
WBPaper00016339
WBPaper00016414
WBPaper00016449
WBPaper00016473
WBPaper00016696
WBPaper00017171
WBPaper00017232
WBPaper00017240
WBPaper00017383
WBPaper00018185
WBPaper00019602
WBPaper00020971
WBPaper00021075
WBPaper00021844
WBPaper00022074
WBPaper00022132
WBPaper00022153
WBPaper00022306
WBPaper00022853
WBPaper00023452
WBPaper00024090
WBPaper00025141
WBPaper00027119
WBPaper00027214
WBPaper00027646
WBPaper00029020
WBPaper00029404
WBPaper00030444
WBPaper00031671
WBPaper00032446
WBPaper00032873
WBPaper00033003
WBPaper00038367
WBPaper00038491
WBPaper00040284
WBPaper00040304
WBPaper00040918
WBPaper00043908
WBPaper00044801
WBPaper00054730
WBPaper00055090
WBPaper00055141
WBPaper00056309
WBPaper00061024
WBPaper00061970
WBPaper00062221
WBPaper00062388
WBPaper00062544
WBPaper00064558
WBPaper00064934
WBPaper00066048
MethodGene