WormBase Tree Display for Gene: WBGene00007710
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| WBGene00007710 | SMap | S_parent | Sequence | C25A1 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | rsa-1 | Person_evidence | WBPerson283 | |||||
| Sequence_name | C25A1.9 | ||||||||
| Molecular_name | C25A1.9a | ||||||||
| C25A1.9a.1 | |||||||||
| CE18532 | |||||||||
| C25A1.9b | |||||||||
| CE08375 | |||||||||
| C25A1.9b.1 | |||||||||
| Other_name | CELE_C25A1.9 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | rsa-1 | ||||||||
| DB_info | Database | WormQTL | gene | WBGene00007710 | |||||
| WormFlux | gene | WBGene00007710 | |||||||
| NDB | locus_tag | CELE_C25A1.9 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00007710|UniProtKB=O02217 | |||||||
| family | PTHR23055 | ||||||||
| NCBI | gene | 172886 | |||||||
| RefSeq | protein | NM_060282.7 | |||||||
| NM_001128952.4 | |||||||||
| SwissProt | UniProtAcc | O02217 | |||||||
| TREEFAM | TREEFAM_ID | TF318412 | |||||||
| UniProt_GCRP | UniProtAcc | O02217 | |||||||
| OMIM | gene | 615902 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:48 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 22 Feb 2007 09:30:12 | WBPerson2970 | Name_change | CGC_name | rsa-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rsa | ||||||||
| Allele (28) | |||||||||
| Strain | WBStrain00034776 | ||||||||
| WBStrain00034777 | |||||||||
| WBStrain00034764 | |||||||||
| WBStrain00007353 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (22) | |||||||||
| Ortholog (28) | |||||||||
| Paralog | WBGene00003563 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| WBGene00003564 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00003565 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00008307 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00008998 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00015867 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00021116 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | rsa-1 encodes a protein phosphatase 2A (PP2A) regulatory subunit of the B'' class; RSA-1 is required for localization of C. elegans PP2A to centrosomes and for mitotic spindle assembly; RSA-1 physically interacts with the LET-92 PP2A catalytic subunit and the PAA-1 PP2A structural subunit; centrosomal levels of PAA-1 are decreased in rsa-1 mutant animals; RSA-1 localizes to centrosomes. | Paper_evidence | WBPaper00041923 | |||||
| WBPaper00028993 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 22 Jan 2013 00:00:00 | ||||||||
| Automated_description | Enables protein phosphatase 2A binding activity. Involved in embryo development; mitotic spindle assembly; and protein localization to organelle. Located in centrosome. Human ortholog(s) of this gene implicated in spermatogenic failure 36. Is an ortholog of human PPP2R3C (protein phosphatase 2 regulatory subunit B''gamma). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0111921 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:17485) | ||||
| Molecular_info | Corresponding_CDS | C25A1.9a | |||||||
| C25A1.9b | |||||||||
| Corresponding_transcript | C25A1.9a.1 | ||||||||
| C25A1.9b.1 | |||||||||
| Other_sequence | CSC01078_1 | ||||||||
| CR04352 | |||||||||
| CRC11344_1 | |||||||||
| CBC08799_1 | |||||||||
| FD515029.1 | |||||||||
| FD514945.1 | |||||||||
| Associated_feature | WBsf643664 | ||||||||
| WBsf976560 | |||||||||
| WBsf976561 | |||||||||
| WBsf984937 | |||||||||
| WBsf1010500 | |||||||||
| WBsf218404 | |||||||||
| Experimental_info | RNAi_result (13) | ||||||||
| Expr_pattern | Expr4518 | ||||||||
| Expr4519 | |||||||||
| Expr15732 | |||||||||
| Expr1013688 | |||||||||
| Expr1033339 | |||||||||
| Expr1145182 | |||||||||
| Expr1200214 | |||||||||
| Expr2015546 | |||||||||
| Expr2033781 | |||||||||
| Drives_construct | WBCnstr00012075 | ||||||||
| WBCnstr00033538 | |||||||||
| Construct_product | WBCnstr00004941 | ||||||||
| WBCnstr00004943 | |||||||||
| WBCnstr00012075 | |||||||||
| WBCnstr00033538 | |||||||||
| Antibody | WBAntibody00001217 | ||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (178) | |||||||||
| Interaction (207) | |||||||||
| Map_info | Map | I | Position | 4.7267 | Error | 0.001652 | |||
| Positive | Positive_clone | C25A1 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (13) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
