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WormBase Tree Display for Gene: WBGene00009368

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Name Class

WBGene00009368SMapS_parentSequenceF33H2
IdentityVersion2
NameCGC_namepole-1Person_evidenceWBPerson320
WBPerson30839
Sequence_nameF33H2.5
Molecular_nameF33H2.5
F33H2.5.1
CE17767
Other_nameCELE_F33H2.5Accession_evidenceNDBBX284601
Public_namepole-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:50WBPerson1971EventImportedInitial conversion from CDS class of WS125
214 Apr 2015 09:52:28WBPerson2970Name_changeCGC_namepole-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpole
Allele (109)
Possibly_affected_byWBVar02152931
StrainWBStrain00001140
WBStrain00035526
WBStrain00054796
RNASeq_FPKM (74)
GO_annotation (33)
Ortholog (52)
Structured_descriptionAutomated_descriptionPredicted to enable DNA binding activity; DNA-directed DNA polymerase activity; and single-stranded DNA 3'-5' DNA exonuclease activity. Predicted to be involved in DNA metabolic process and mitotic cell cycle. Predicted to be located in nucleus. Predicted to be part of epsilon DNA polymerase complex. Human ortholog(s) of this gene implicated in ascending colon cancer; carcinoma (multiple); and mismatch repair cancer syndrome. Is an ortholog of human POLE (DNA polymerase epsilon, catalytic subunit).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:9256Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9177)
DOID:3908Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9177)
DOID:2871Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9177)
DOID:218Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9177)
DOID:1324Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9177)
DOID:3907Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9177)
DOID:1380Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9177)
DOID:0112182Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9177)
Molecular_infoCorresponding_CDSF33H2.5
Corresponding_transcriptF33H2.5.1
Other_sequence (12)
Associated_featureWBsf976630
WBsf986297
WBsf986298
WBsf1011328
WBsf220675
Experimental_infoRNAi_result (14)
Expr_patternExpr5945
Expr1013626
Expr1034102
Expr1150129
Expr2014990
Expr2033225
Drives_constructWBCnstr00002036
WBCnstr00032247
Construct_productWBCnstr00032247
Microarray_results (19)
Expression_cluster (155)
Interaction (164)
Map_infoMapIPosition29.2714
PositivePositive_cloneF33H2Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00023755
WBPaper00026064
WBPaper00029334
WBPaper00038491
WBPaper00055090
WBPaper00062439
WBPaper00064339
WBPaper00066002
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene