WormBase Tree Display for Gene: WBGene00017464
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WBGene00017464 | SMap | S_parent | Sequence | F14D12 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | sulp-2 | Person_evidence | WBPerson2233 | |||||
Sequence_name | F14D12.5 | ||||||||
Molecular_name | F14D12.5 | ||||||||
F14D12.5.1 | |||||||||
CE27963 | |||||||||
Other_name | CELE_F14D12.5 | Accession_evidence | NDB | BX284606 | |||||
Public_name | sulp-2 | ||||||||
DB_info | Database | AceView | gene | XG216 | |||||
WormQTL | gene | WBGene00017464 | |||||||
WormFlux | gene | WBGene00017464 | |||||||
NDB | locus_tag | CELE_F14D12.5 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00017464|UniProtKB=G5EDS5 | |||||||
family | PTHR11814 | ||||||||
NCBI | gene | 180828 | |||||||
RefSeq | protein | NM_076543.7 | |||||||
TrEMBL | UniProtAcc | G5EDS5 | |||||||
UniProt_GCRP | UniProtAcc | G5EDS5 | |||||||
OMIM | gene | 126650 | |||||||
604943 | |||||||||
605646 | |||||||||
610130 | |||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 28 May 2004 13:30:58 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
2 | 19 Jan 2005 16:30:54 | WBPerson2970 | Name_change | CGC_name | sulp-2 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | sulp | ||||||||
Allele (50) | |||||||||
Strain | WBStrain00032065 | ||||||||
WBStrain00032068 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (20) | |||||||||
Ortholog (44) | |||||||||
Paralog | WBGene00010788 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00010789 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00012259 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00013963 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00016945 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00018283 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00020914 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | sulp-2 encodes one of eight C. elegans members of the sulfate permease family of anion transporters; by homology, SULP-2 is predicted to function as an anion transporter that regulates cellular pH and volume via transmembrane movement of electrolytes and fluids and when expressed in Xenopus oocytes, SULP-2 does exhibit modest uptake of sulfate; a SULP-2::GFP fusion is expressed in the intestine and rectal gland cells, where it localizes to the basolateral membrane and in cephalic and deirid neurons, where it localizes to sensillar endings. | Paper_evidence | WBPaper00025075 | |||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 13 Sep 2006 00:00:00 | ||||||||
Automated_description | Enables sulfate transmembrane transporter activity. Predicted to be involved in inorganic anion transmembrane transport and organic anion transport. Located in basolateral plasma membrane and non-motile cilium. Expressed in dopaminergic neurons and intestine. Human ortholog(s) of this gene implicated in several diseases, including Pendred Syndrome; autosomal recessive nonsyndromic deafness (multiple); and calcium oxalate nephrolithiasis. Is an ortholog of several human genes including SLC26A1 (solute carrier family 26 member 1); SLC26A3 (solute carrier family 26 member 3); and SLC26A4 (solute carrier family 26 member 4). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:12176 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8818) | ||||
DOID:0060744 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8818) | ||||||
DOID:0060296 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3018) | ||||||
DOID:0110498 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8818) | ||||||
DOID:0110513 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9359) | ||||||
DOID:0080652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10993) | ||||||
DOID:13250 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3018) | ||||||
Molecular_info | Corresponding_CDS | F14D12.5 | |||||||
Corresponding_transcript | F14D12.5.1 | ||||||||
Other_sequence | CJC12795_1 | ||||||||
Associated_feature | WBsf670538 | ||||||||
WBsf237387 | |||||||||
Experimental_info | RNAi_result | WBRNAi00000992 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00030931 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00013264 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00044586 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr3247 | ||||||||
Expr3259 | |||||||||
Expr1010356 | |||||||||
Expr1148543 | |||||||||
Expr2017113 | |||||||||
Expr2035249 | |||||||||
Drives_construct | WBCnstr00011250 | ||||||||
WBCnstr00011262 | |||||||||
WBCnstr00027278 | |||||||||
Construct_product | WBCnstr00011262 | ||||||||
WBCnstr00027278 | |||||||||
Microarray_results (18) | |||||||||
Expression_cluster (152) | |||||||||
Interaction (24) | |||||||||
Map_info | Map | X | Position | -4.46315 | Error | 0.008938 | |||
Positive | Positive_clone | F14D12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Mapping_data | Multi_point | 5231 | |||||||
Pseudo_map_position | |||||||||
Reference | WBPaper00025075 | ||||||||
WBPaper00035539 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00055090 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |