WormBase Tree Display for Gene: WBGene00012665
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| WBGene00012665 | SMap | S_parent | Sequence | Y39B6A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | pph-5 | Person_evidence | WBPerson3827 | |||||
| Sequence_name | Y39B6A.2 | ||||||||
| Molecular_name | Y39B6A.2a | ||||||||
| Y39B6A.2a.1 | |||||||||
| CE36619 | |||||||||
| Y39B6A.2b | |||||||||
| CE45307 | |||||||||
| Y39B6A.2b.1 | |||||||||
| Other_name | CELE_Y39B6A.2 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | pph-5 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:54 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 15 May 2006 09:09:13 | WBPerson2970 | Name_change | CGC_name | pph-5 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | pph | ||||||||
| Allele (241) | |||||||||
| Strain | WBStrain00033197 | ||||||||
| WBStrain00052057 | |||||||||
| WBStrain00052058 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (23) | |||||||||
| Ortholog (41) | |||||||||
| Paralog (44) | |||||||||
| Structured_description | Concise_description | pph-5 encodes a protein phosphatase that is the sole C. elegans ortholog of protein phosphatase 5; during anaphase, PPH-5 negatively regulates the cortical granule exocytosis and cytokinesis activities of SEP-1/separase; in this capactiy, PPH-5 appears to function to regulate SEP-1 localization to vesicles at the appropriate times during cell division; pph-5 is expressed throughout development in both the soma and the germ line; in the germ line, a GFP::PPH-5 is cytoplasmic during interphase, becomes enriched at the spindle matrix during mitosis, and then disperses from the spindle during anaphase. | Paper_evidence | WBPaper00040142 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 01 Sep 2011 00:00:00 | ||||||||
| Automated_description | Enables Hsp90 protein binding activity and phosphoprotein phosphatase activity. Involved in negative regulation of exocytosis and protein localization to organelle. Located in cytoplasm; mitotic spindle; and protein-containing complex. Expressed in several structures, including touch receptor neurons. Is an ortholog of human PPP5C (protein phosphatase 5 catalytic subunit). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y39B6A.2a | |||||||
| Y39B6A.2b | |||||||||
| Corresponding_CDS_history | Y39B6A.2:wp123 | ||||||||
| Corresponding_transcript | Y39B6A.2a.1 | ||||||||
| Y39B6A.2b.1 | |||||||||
| Other_sequence (98) | |||||||||
| Associated_feature (12) | |||||||||
| Experimental_info | RNAi_result (16) | ||||||||
| Expr_pattern | Expr6949 | ||||||||
| Expr9665 | |||||||||
| Expr9666 | |||||||||
| Expr15093 | |||||||||
| Expr1024871 | |||||||||
| Expr1035600 | |||||||||
| Expr1159678 | |||||||||
| Expr2015014 | |||||||||
| Expr2033249 | |||||||||
| Drives_construct | WBCnstr00002374 | ||||||||
| WBCnstr00008995 | |||||||||
| WBCnstr00014199 | |||||||||
| WBCnstr00014200 | |||||||||
| Construct_product | WBCnstr00008994 | ||||||||
| WBCnstr00014199 | |||||||||
| Antibody | WBAntibody00002287 | ||||||||
| Microarray_results (24) | |||||||||
| Expression_cluster (82) | |||||||||
| Interaction (162) | |||||||||
| Map_info | Map | V | Position | 20.2152 | Error | 0.001462 | |||
| Positive | Positive_clone | Y39B6A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (17) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
