WormBase Tree Display for Gene: WBGene00012759
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| WBGene00012759 | SMap | S_parent | Sequence | Y41C4A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | sup-1 | Paper_evidence | WBPaper00041593 | |||||
| Person_evidence | WBPerson201 | ||||||||
| Sequence_name | Y41C4A.13 | ||||||||
| Molecular_name | Y41C4A.13 | ||||||||
| Y41C4A.13.1 | |||||||||
| CE20253 | |||||||||
| Other_name | CELE_Y41C4A.13 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | sup-1 | ||||||||
| DB_info | Database | AceView | gene | 3M822 | |||||
| WormQTL | gene | WBGene00012759 | |||||||
| WormFlux | gene | WBGene00012759 | |||||||
| NDB | locus_tag | CELE_Y41C4A.13 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00012759|UniProtKB=Q9XWU2 | |||||||
| family | PTHR34149 | ||||||||
| NCBI | gene | 189815 | |||||||
| RefSeq | protein | NM_067119.7 | |||||||
| SwissProt | UniProtAcc | Q9XWU2 | |||||||
| TREEFAM | TREEFAM_ID | TF319571 | |||||||
| UniProt_GCRP | UniProtAcc | Q9XWU2 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:54 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 12 Oct 2012 15:09:29 | WBPerson2970 | Event | Acquires_merge | WBGene00006312 | ||||
| Name_change | CGC_name | sup-1 | |||||||
| Acquires_merge | WBGene00006312 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | sup | ||||||||
| Reference_allele | WBVar00143668 | ||||||||
| Allele (115) | |||||||||
| Legacy_information | e995dm : dominant suppressor of unc-17(e245); does not suppress unc-17(e876); no phenotype alone. ES3 in presence of e245 ME3. NA > 5 (e995xri etc. : all resemble e995). | ||||||||
| See also e995, e996, e1826, e1827, e1909, e1955 | |||||||||
| [C.elegansII] e995dm : dominant allele-specific suppressor of unc-17(e245); does not suppress unc-17(e876); no phenotype alone. ES3 in presence of e245 ME3. OA>5: e996xri, e1827, e1955 etc. (all similar). [CB; RM] | |||||||||
| Strain | WBStrain00033410 | ||||||||
| WBStrain00033411 | |||||||||
| WBStrain00033415 | |||||||||
| WBStrain00033416 | |||||||||
| WBStrain00004371 | |||||||||
| WBStrain00004632 | |||||||||
| WBStrain00023506 | |||||||||
| WBStrain00023498 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (15) | |||||||||
| Ortholog (25) | |||||||||
| Paralog | WBGene00007474 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WBGene00009915 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00010598 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00011220 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00044477 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| WBGene00194747 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00018348 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00194733 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00022698 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00044756 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| Structured_description | Concise_description | sup-1 encodes a novel, single-pass transmembrane protein; sup-1 was identified as an allele-specific dominant suppressor of unc-17(e245); unc-17 encodes a synaptic vesicle acetylcholine transporter and the e245 missense mutation results in substitution of arginine for glycine in the ninth transmembrane domain and reduced levels of UNC-17 protein; sup-1 is defined by several alleles that all behave similarly as dominant suppressors of unc-17(e245) and have no phenotype on their own; SUP-1 reporter fusion proteins are expressed in cholinergic neurons and body wall muscles, where they localize to the plasma membrane and are found in synaptic regions. | Paper_evidence | WBPaper00004985 | |||||
| WBPaper00002665 | |||||||||
| WBPaper00041593 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 04 Dec 2012 00:00:00 | ||||||||
| Automated_description | Located in neuron projection; neuronal cell body membrane; and synapse. Expressed in body wall musculature; neurons; and ventral nerve cord. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y41C4A.13 | |||||||
| Corresponding_transcript | Y41C4A.13.1 | ||||||||
| Other_sequence (27) | |||||||||
| Associated_feature | WBsf717994 | ||||||||
| WBsf994480 | |||||||||
| WBsf994481 | |||||||||
| WBsf1016074 | |||||||||
| WBsf1016075 | |||||||||
| WBsf227597 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00020471 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00006756 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00036994 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00056355 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr10560 | ||||||||
| Expr1028714 | |||||||||
| Expr1035644 | |||||||||
| Expr1159840 | |||||||||
| Expr2017128 | |||||||||
| Expr2035264 | |||||||||
| Drives_construct | WBCnstr00015438 | ||||||||
| WBCnstr00015440 | |||||||||
| WBCnstr00015444 | |||||||||
| WBCnstr00015445 | |||||||||
| WBCnstr00015446 | |||||||||
| WBCnstr00015447 | |||||||||
| WBCnstr00015759 | |||||||||
| Construct_product | WBCnstr00015438 | ||||||||
| WBCnstr00015440 | |||||||||
| WBCnstr00015441 | |||||||||
| WBCnstr00015444 | |||||||||
| WBCnstr00015445 | |||||||||
| WBCnstr00015446 | |||||||||
| WBCnstr00015447 | |||||||||
| WBCnstr00015759 | |||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (209) | |||||||||
| Interaction (16) | |||||||||
| Map_info | Positive | Positive_clone | Y41C4A | Inferred_automatically | From sequence, transcript, pseudogene data | ||||
| Mapping_data | 2_point | 77 | |||||||
| 89 | |||||||||
| Multi_point | 92 | ||||||||
| 1660 | |||||||||
| 2028 | |||||||||
| 2029 | |||||||||
| Interpolated_map_position | III | 12.044 | |||||||
| Reference | WBPaper00037329 | ||||||||
| WBPaper00039285 | |||||||||
| WBPaper00041593 | |||||||||
| WBPaper00043425 | |||||||||
| WBPaper00058518 | |||||||||
| WBPaper00061353 | |||||||||
| Method | Gene |
