WormBase Tree Display for Gene: WBGene00013854
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| WBGene00013854 | SMap | S_parent | Sequence | ZC116 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | cyc-2.2 | Person_evidence | WBPerson338 | |||||
| Sequence_name | ZC116.2 | ||||||||
| Molecular_name | ZC116.2 | ||||||||
| ZC116.2.1 | |||||||||
| CE06565 | |||||||||
| Other_name | CELE_ZC116.2 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | cyc-2.2 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:55 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 09 Mar 2007 14:55:52 | WBPerson2970 | Name_change | CGC_name | cyc-2.2 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cyc | ||||||||
| Allele (20) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00077721 | ||||||||
| 00077722 | |||||||||
| 00077723 | |||||||||
| 00077724 | |||||||||
| 00077725 | |||||||||
| 00077726 | |||||||||
| 00077727 | |||||||||
| 00120602 | |||||||||
| 00120603 | |||||||||
| Ortholog (47) | |||||||||
| Paralog | WBGene00017121 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | cyc-2.2 encodes, along with cyc-2.1, one of two C. elegans cytochrome c proteins; the product of cyc-2.2 is predicted to function in the electron transport chain by transferring electrons from respiratory chain Complex III to Complex IV; RNAi screens indicate the cyc-2.2 activity is required for embryonic development as well as for normal body size and rates of growth. | Paper_evidence | WBPaper00005654 | |||||
| WBPaper00024944 | |||||||||
| WBPaper00025054 | |||||||||
| WBPaper00041884 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 25 Mar 2013 00:00:00 | ||||||||
| Automated_description | Predicted to enable electron transfer activity; heme binding activity; and metal ion binding activity. Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen and mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to be located in mitochondrial intermembrane space. Human ortholog(s) of this gene implicated in several diseases, including Huntington's disease; carcinoma (multiple); and thrombocytopenia. Is an ortholog of human CYCS (cytochrome c, somatic). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:4947 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:19986) | ||||
| DOID:1588 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:19986) | ||||||
| DOID:3908 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:19986) | ||||||
| DOID:12858 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:19986) | ||||||
| DOID:1793 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:19986) | ||||||
| DOID:3907 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:19986) | ||||||
| Molecular_info | Corresponding_CDS | ZC116.2 | |||||||
| Corresponding_transcript | ZC116.2.1 | ||||||||
| Other_sequence (32) | |||||||||
| Associated_feature | WBsf234705 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00112910 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00037945 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00063771 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00063761 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00058718 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00112850 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00021559 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00112790 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1025942 | ||||||||
| Expr1162140 | |||||||||
| Expr2010652 | |||||||||
| Expr2028892 | |||||||||
| Drives_construct | WBCnstr00029500 | ||||||||
| Construct_product | WBCnstr00029500 | ||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (197) | |||||||||
| Interaction (381) | |||||||||
| Map_info | Map | V | Position | 4.52788 | Error | 0.002099 | |||
| Positive | Positive_clone | ZC116 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00031039 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00041884 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
