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WormBase Tree Display for Gene: WBGene00015484

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Name Class

WBGene00015484SMapS_parentSequenceC05D11
IdentityVersion2
NameCGC_nameatgl-1Person_evidenceWBPerson542
WBPerson2105
Sequence_nameC05D11.7
Molecular_nameC05D11.7a
C05D11.7a.1
CE29663
C05D11.7b
CE30480
C05D11.7b.1
Other_nameCELE_C05D11.7Accession_evidenceNDBBX284603
Public_nameatgl-1
DB_infoDatabase (14)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:56WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
208 Oct 2013 11:58:44WBPerson2970Name_changeCGC_nameatgl-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classatgl
Allele (47)
RNASeq_FPKM (74)
GO_annotation (26)
Ortholog (50)
ParalogWBGene00008370Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00015241Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionAutomated_descriptionPredicted to enable triglyceride lipase activity. Predicted to be involved in lipid homeostasis and triglyceride catabolic process. Located in lipid droplet. Expressed in intestine; nerve ring; and ventral nerve cord. Used to study Chanarin-Dorfman syndrome. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive congenital ichthyosis 10; liver disease (multiple); and type 2 diabetes mellitus. Is an ortholog of human PNPLA2 (patatin like phospholipase domain containing 2) and PNPLA3 (patatin like phospholipase domain containing 3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:0050729Homo sapiensPaper_evidenceWBPaper00060484
Curator_confirmedWBPerson324
Date_last_updated17 May 2022 00:00:00
Potential_modelDOID:9452Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:18590)
DOID:0060719Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:21246)
DOID:9352Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:18590)
DOID:5082Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:18590)
DOID:0080208Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:18590)
DOID:3393Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:18590)
DOID:684Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:18590)
Models_disease_assertedWBDOannot00001199
WBDOannot00001200
Molecular_infoCorresponding_CDSC05D11.7a
C05D11.7b
Corresponding_transcriptC05D11.7a.1
C05D11.7b.1
Other_sequence (46)
Associated_feature (18)
Experimental_infoRNAi_result (31)
Expr_patternExpr5175
Expr12050
Expr15277
Expr1025379
Expr1036622
Expr1143831
Expr2009497
Expr2027734
Drives_constructWBCnstr00004164
WBCnstr00018586
WBCnstr00042154
Construct_productWBCnstr00020375
WBCnstr00020376
WBCnstr00020377
WBCnstr00020378
WBCnstr00020379
WBCnstr00020380
WBCnstr00020395
AntibodyWBAntibody00002631
WBAntibody00002640
Microarray_results (30)
Expression_cluster (127)
Interaction (38)
WBProcessWBbiopr:00000121
Map_infoMapIIIPosition-1.28286
PositivePositive_cloneC05D11Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (37)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene