WormBase Tree Display for Gene: WBGene00017686
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| WBGene00017686 | SMap | S_parent | Sequence | F21H12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | tpp-2 | Person_evidence | WBPerson260 | |||||
| Sequence_name | F21H12.6 | ||||||||
| Molecular_name | F21H12.6 | ||||||||
| F21H12.6.1 | |||||||||
| CE01917 | |||||||||
| Other_name | CELE_F21H12.6 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | tpp-2 | ||||||||
| DB_info | Database (14) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:59 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 04 Sep 2012 12:07:47 | WBPerson2970 | Name_change | CGC_name | tpp-2 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | tpp | ||||||||
| Allele (70) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (12) | |||||||||
| Ortholog (37) | |||||||||
| Paralog | WBGene00000088 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| WBGene00000254 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00001172 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00002232 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | F21H12.6 encodes the C. elegans tripeptidyl peptidase II ortholog; loss of F21H12.6 activity via RNAi indicates that the product of F21H12.6 promotes fat formation; an F21H12.6::GFP reporter fusion is expressed in the intestine, the site of fat storage, and in a subset of nerve ring neurons. | Paper_evidence | WBPaper00031090 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 15 Oct 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable tripeptidyl-peptidase activity. Involved in positive regulation of lipid storage. Predicted to be located in cytosol. Expressed in intestine and nerve ring. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is an ortholog of human TPP2 (tripeptidyl peptidase 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12016) | ||||
| Molecular_info | Corresponding_CDS | F21H12.6 | |||||||
| Corresponding_transcript | F21H12.6.1 | ||||||||
| Other_sequence (19) | |||||||||
| Associated_feature | WBsf650111 | ||||||||
| WBsf665586 | |||||||||
| WBsf665587 | |||||||||
| WBsf988054 | |||||||||
| WBsf988055 | |||||||||
| WBsf223130 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00066483 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00013711 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00066482 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00045251 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr4996 | ||||||||
| Expr1028809 | |||||||||
| Expr1037591 | |||||||||
| Expr1149179 | |||||||||
| Expr2017467 | |||||||||
| Expr2035606 | |||||||||
| Drives_construct | WBCnstr00012399 | ||||||||
| WBCnstr00027102 | |||||||||
| Construct_product | WBCnstr00027102 | ||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (122) | |||||||||
| Interaction (38) | |||||||||
| Map_info | Map | II | Position | -0.510756 | |||||
| Positive | Positive_clone | F21H12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00031090 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00049828 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
