WormBase Tree Display for Gene: WBGene00019314

WBGene00019314 SMap: S_parent: Sequence: K02E7
  Identity: Version: 1
    Name: Sequence_name: K02E7.10
      Molecular_name: K02E7.10
        K02E7.10.1
        CE11640
      Other_name: CELE_K02E7.10 Accession_evidence: NDB BX284602
      Public_name: K02E7.10
    DB_info: Database: AceView gene 2B354
        WormQTL gene WBGene00019314
        WormFlux gene WBGene00019314
        NDB locus_tag CELE_K02E7.10
        Panther gene CAEEL|WormBase=WBGene00019314|UniProtKB=O17255
          family PTHR12411
        NCBI gene 186889
        RefSeq protein NM_061503.2
        TrEMBL UniProtAcc O17255
        UniProt_GCRP UniProtAcc O17255
        OMIM gene 601105
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:01 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (46)
    RNASeq_FPKM (74)
    GO_annotation: 00029545
      00029546
      00029547
      00029548
      00124191
      00124192
    Ortholog (47)
    Paralog (28)
    Structured_description: Automated_description: Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Down syndrome; Huntington's disease; and cerebrovascular disease (multiple). Is an ortholog of human CTSH (cathepsin H); CTSK (cathepsin K); and CTSS (cathepsin S). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2545)
      DOID:2378 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2545)
      DOID:3407 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2545)
      DOID:2671 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2535)
      DOID:14250 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2545)
      DOID:870 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2545)
      DOID:0080038 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2536)
      DOID:10941 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2536,HGNC:2545)
      DOID:3068 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2535)
      DOID:12858 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2535)
  Molecular_info: Corresponding_CDS: K02E7.10
    Corresponding_transcript: K02E7.10.1
    Associated_feature: WBsf986559
      WBsf986560
      WBsf1011474
      WBsf1011475
  Experimental_info: RNAi_result: WBRNAi00049726 Inferred_automatically: RNAi_primary
      WBRNAi00033878 Inferred_automatically: RNAi_primary
      WBRNAi00076540 Inferred_automatically: RNAi_primary
      WBRNAi00016471 Inferred_automatically: RNAi_primary
      WBRNAi00115188 Inferred_automatically: RNAi_primary
      WBRNAi00089104 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1012047
      Expr1153448
      Expr2004704
      Expr2022926
    Drives_construct: WBCnstr00025925
    Construct_product: WBCnstr00025925
    Microarray_results (14)
    Expression_cluster (133)
    Interaction: WBInteraction000137618
      WBInteraction000151537
      WBInteraction000174814
      WBInteraction000248636
      WBInteraction000288071
      WBInteraction000316197
      WBInteraction000354482
      WBInteraction000368435
      WBInteraction000414817
      WBInteraction000424577
  Map_info: Positive: Positive_clone: K02E7 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: II -15.5698
  Reference: WBPaper00038491
    WBPaper00055090
  Method: Gene