WormBase Tree Display for Gene: WBGene00044621

WBGene00044621 SMap: S_parent: Sequence: F53B1
  Identity: Version: 2
    Name: CGC_name: bus-5 Person_evidence: WBPerson261
      Sequence_name: F53B1.4
      Molecular_name: F53B1.4
        F53B1.4.1
        CE04644
      Other_name: CELE_F53B1.4 Accession_evidence: NDB BX284606
      Public_name: bus-5
    DB_info: Database: NDB locus_tag CELE_F53B1.4
        NCBI gene 180525
        RefSeq protein NM_075989.3
        TREEFAM TREEFAM_ID TF313892
        TrEMBL UniProtAcc Q20697
        UniProt_GCRP UniProtAcc Q20697
        OMIM gene 616146
    Species: Caenorhabditis elegans
    History: Version_change: 1 01 Sep 2005 10:24:02 WBPerson2970 Event: Created
        2 30 Jul 2020 16:54:45 WBPerson1983 Event: Acquires_merge: WBGene00018737
      Acquires_merge: WBGene00018737
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: bus
    Reference_allele: WBVar00144919
    Allele (37)
    Strain: WBStrain00004659
      WBStrain00004661
      WBStrain00004730
      WBStrain00004731
      WBStrain00004762
      WBStrain00005604
    RNASeq_FPKM (74)
    Ortholog (30)
    Paralog (13)
    Structured_description: Concise_description: bus-5 is an uncloned gene required for colonization by Microbacterium nematophilum, the tail-swelling response to M. nematophilum infection, and for fully normal cuticle antigens and traction during movement; bus-5 is also strongly required for cuticle integrity and for long-term survival during starvation. Paper_evidence: WBPaper00026735
            WBPaper00029153
          Curator_confirmed: WBPerson567
          Date_last_updated: 16 Jul 2007 00:00:00
      Automated_description: Expressed in hyp7 syncytium; hypodermal cell; and seam cell. Human ortholog(s) of this gene implicated in Catel Manzke syndrome. Is predicted to encode a protein with the following domains: NAD(P)-binding domain; NAD(P)-binding domain superfamily; and GDP-mannose 4,6 dehydratase. Is an ortholog of human TGDS (TDP-glucose 4,6-dehydratase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0081122 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:20324)
  Molecular_info: Corresponding_CDS: F53B1.4
    Corresponding_transcript: F53B1.4.1
    Other_sequence (57)
    Associated_feature: WBsf237051
      WBsf237052
  Experimental_info: RNAi_result: WBRNAi00015469 Inferred_automatically: RNAi_primary
      WBRNAi00032665 Inferred_automatically: RNAi_primary
      WBRNAi00025578 Inferred_automatically: RNAi_primary
      WBRNAi00048070 Inferred_automatically: RNAi_primary
      WBRNAi00025577 Inferred_automatically: RNAi_primary
      WBRNAi00027359 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr15742
      Expr15743
      Expr15744
      Expr16442
      Expr1014478
      Expr1038066
      Expr1151881
      Expr2004032
      Expr2022254
    Drives_construct: WBCnstr00026306
      WBCnstr00042503
      WBCnstr00042504
      WBCnstr00043024
    Construct_product: WBCnstr00026306
    Microarray_results (18)
    Expression_cluster (268)
    Interaction: WBInteraction000538982
      WBInteraction000558533
      WBInteraction000565990
      WBInteraction000576110
      WBInteraction000576669
      WBInteraction000579498
    WBProcess: WBbiopr:00000039
  Map_info: Map: X Position: -17.0437
    Positive: Positive_clone: F53B1 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 5461
  Reference (12)
  Remark: [2020-07-30T16:54:45.386Z WBPerson1983] Gene Merged: bus-5 confirmed as this sequenced loci also known as rml-2 Curator_confirmed: WBPerson1983
  Method: Gene