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WormBase Tree Display for Gene: WBGene00220250

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Name Class

WBGene00220250SMapS_parentSequenceC09B9
IdentityVersion1
NameSequence_nameC09B9.85
Molecular_nameC09B9.85
C09B9.85.1
CE47744
Other_nameCELE_C09B9.85Accession_evidenceNDBBX284604
Public_nameC09B9.85
DB_infoDatabaseNDBlocus_tagCELE_C09B9.85
PanthergeneCAEEL|WormBase=WBGene00220250|UniProtKB=J7RNL4
familyPTHR10736
NCBIgene24104191
RefSeqproteinNM_001276822.2
TrEMBLUniProtAccJ7RNL4
UniProt_GCRPUniProtAccJ7RNL4
OMIMgene607854
SpeciesCaenorhabditis elegans
HistoryVersion_change117 Aug 2012 09:56:12WBPerson1849EventSplit_fromWBGene00015628
Split_fromWBGene00015628
StatusLive
Gene_infoBiotypeSO:0001217
Allele (50)
RNASeq_FPKM (74)
GO_annotation (13)
Ortholog (30)
Paralog (26)
Structured_descriptionAutomated_descriptionPredicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Human ortholog(s) of this gene implicated in autosomal dominant vitreoretinochoroidopathy and retinal degeneration (multiple). Is an ortholog of several human genes including BEST1 (bestrophin 1); BEST2 (bestrophin 2); and BEST3 (bestrophin 3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0110396Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12703)
DOID:4448Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12703)
DOID:0050661Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12703)
DOID:0050662Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12703)
DOID:0111569Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12703)
Molecular_infoCorresponding_CDSC09B9.85
Corresponding_transcriptC09B9.85.1
Other_sequenceHbac_isotig00865
Experimental_infoRNAi_resultWBRNAi00000596Inferred_automaticallyRNAi_primary
WBRNAi00010512Inferred_automaticallyRNAi_primary
WBRNAi00040166Inferred_automaticallyRNAi_primary
Expr_patternExpr2000640
Expr2018864
Microarray_results (16)
Expression_clusterWBPaper00045521:Spermatogenic
WBPaper00049498:npr-1(ur89)_regulated_1
WBPaper00050231:male_enriched
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053599:female_vs_male_downregulated
WBPaper00053810:isp-1(qm150)_downregulated
WBPaper00055354:Psora-Allantoin_upregulated
WBPaper00055354:Rapamycin-Metformin_upregulated
WBPaper00055354:Rifampicin-Allantoin_upregulated
WBPaper00055354:Rifampicin-Psora_upregulated
WBPaper00055354:Rifampicin_upregulated
WBPaper00055804:FBF-1-FBF-2-associated_spermatogenic-enriched
WBPaper00056161:male_enriched_siRNA
WBPaper00056284:ints-9(RNAi)_upregulated
WBPaper00056330:glycine_downregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056809:smn-1(ok355)_downregulated
WBPaper00057196:raga-1(ok386)_downregulated)
WBPaper00058955:heatshock_upregulated_CE
WBPaper00059117:B.subtilis_upregulated
WBPaper00060014:set-2(tm1630)_downregulated
WBPaper00060683:hlh-11(ko1)_upregulated
WBPaper00060764:swsn-1(os22ts)_upregulated
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00061340:Tail_hypodermis
WBPaper00061439:unc-30(ok613)_downregulated
WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
WBPaper00061653:alh-4(hj221)_downregulated
WBPaper00061753:csr-1(tor159)_downregulated_25C
WBPaper00062118:neural-HSF-1_downregulated
WBPaper00062156:jmjd-1.2(zr1010)_upregulated
WBPaper00062156:jmjd-5(zr1234)_upregulated
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062193:daf-16(RNAi)_downregulated
WBPaper00062446:nhr-8(hd117)_upregulated
WBPaper00062456:doxycycline_upregulated_CB4856_transcript
WBPaper00062456:doxycycline_upregulated_N2_transcript
WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064602:egl-9(sa307)_downregulated
WBPaper00064632:daf-2(e1370)_upregulated_intestine
WBPaper00064716:paraquat_downregulated
WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
WBPaper00065086:JU1400_N.ferruginous_regulated
WBPaper00065086:N2_N.ferruginous_regulated
WBPaper00065096:25C_vs_20C_downregulated
WBPaper00065096:Day10_vs_Day1_downregulated
WBPaper00065096:npr-8(ok1439)_downregulated_Day1_20C
WBPaper00065096:npr-8(ok1439)_upregulated_Day10_20C
WBPaper00066004:tdp-1(csb38)_upregulated
WBPaper00066038:mip-1(how5)_upregulated
WBPaper00066110:Cisplatin_upregulated_diploid
WBPaper00066110:Doxorubicin_upregulated_diploid
WBPaper00066110:tetraploid_vs_diploid_upregulated
cgc4489_group_19
WBPaper00005124:estrogen_10-5M_regulated
WBPaper00013489:Ray_Enriched
WBPaper00026929:Resveratrol_regulated_daf-16
WBPaper00031850:mdt-15(RNAi)_downregulated
WBPaper00036130:mir-243_up_regulated
WBPaper00036286:Pattern_G
WBPaper00038172:tax-6null_down_regulated
WBPaper00040858:eQTL_regulated_developing
WBPaper00045294:50uM_TBBP_upregulated
WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
WBPaper00048989:N2_rapamycin_upregulated
[cgc6390]:spermatogenesis-enriched
Map_infoPositivePositive_cloneC09B9Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionIV1.41957
ReferenceWBPaper00055090
MethodGene