WormBase Tree Display for Gene: WBGene00220250

WBGene00220250 SMap: S_parent: Sequence: C09B9
  Identity: Version: 1
    Name: Sequence_name: C09B9.85
      Molecular_name: C09B9.85
        C09B9.85.1
        CE47744
      Other_name: CELE_C09B9.85 Accession_evidence: NDB BX284604
      Public_name: C09B9.85
    DB_info: Database: NDB locus_tag CELE_C09B9.85
        Panther gene CAEEL|WormBase=WBGene00220250|UniProtKB=J7RNL4
          family PTHR10736
        NCBI gene 24104191
        RefSeq protein NM_001276822.2
        TrEMBL UniProtAcc J7RNL4
        UniProt_GCRP UniProtAcc J7RNL4
        OMIM gene 607854
    Species: Caenorhabditis elegans
    History: Version_change: 1 17 Aug 2012 09:56:12 WBPerson1849 Event: Split_from: WBGene00015628
      Split_from: WBGene00015628
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (50)
    RNASeq_FPKM (74)
    GO_annotation (13)
    Ortholog: WBGene00222902 Brugia malayi From_analysis: WormBase-Compara
      WBGene00231064 Brugia malayi From_analysis: WormBase-Compara
      CSP21.g515 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g13647 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g14593 Panagrellus redivivus From_analysis: WormBase-Compara
      Pan_g14597 Panagrellus redivivus From_analysis: WormBase-Compara
      Pan_g18195 Panagrellus redivivus From_analysis: WormBase-Compara
      WBGene00096811 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00097156 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00113768 Pristionchus pacificus From_analysis: WormBase-Compara
      chrIV_pilon.g10338 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00239127 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00245381 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00248837 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00281086 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00266360 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00267773 Strongyloides ratti From_analysis: WormBase-Compara
      ZFIN:ZDB-GENE-110411-214 Danio rerio From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      ZFIN:ZDB-GENE-070912-6 Danio rerio From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      HGNC:12703 Homo sapiens From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      HGNC:17107 Homo sapiens From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      HGNC:17105 Homo sapiens From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      HGNC:17106 Homo sapiens From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      MGI:1346332 Mus musculus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      MGI:2387588 Mus musculus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      MGI:3580298 Mus musculus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      RGD:1311656 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      RGD:1305439 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      RGD:1305377 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      RGD:1596200 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
    Paralog (26)
    Structured_description: Automated_description: Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Human ortholog(s) of this gene implicated in autosomal dominant vitreoretinochoroidopathy and retinal degeneration (multiple). Is an ortholog of several human genes including BEST1 (bestrophin 1); BEST2 (bestrophin 2); and BEST3 (bestrophin 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0110396 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12703)
      DOID:4448 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12703)
      DOID:0050661 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12703)
      DOID:0050662 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12703)
      DOID:0111569 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12703)
  Molecular_info: Corresponding_CDS: C09B9.85
    Corresponding_transcript: C09B9.85.1
    Other_sequence: Hbac_isotig00865
  Experimental_info: RNAi_result: WBRNAi00000596 Inferred_automatically: RNAi_primary
      WBRNAi00010512 Inferred_automatically: RNAi_primary
      WBRNAi00040166 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr2000640
      Expr2018864
    Microarray_results (16)
    Expression_cluster (67)
  Map_info: Positive: Positive_clone: C09B9 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: IV 1.41957
  Reference: WBPaper00055090
  Method: Gene