WormBase Tree Display for Gene: WBGene00306126
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| WBGene00306126 | SMap | S_parent | Sequence | Y54F10AM | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | cone-1 | Person_evidence | WBPerson260 | |||||
| Curator_confirmed | WBPerson21950 | ||||||||
| Laboratory_evidence | OH | ||||||||
| Sequence_name | Y54F10AM.16 | ||||||||
| Molecular_name | Y54F10AM.16a | ||||||||
| Y54F10AM.16a.1 | |||||||||
| CE32988 | |||||||||
| Y54F10AM.16b | |||||||||
| CE32987 | |||||||||
| Y54F10AM.16b.1 | |||||||||
| Other_name | CELE_Y54F10AM.16 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | cone-1 | ||||||||
| DB_info | Database | NDB | locus_tag | CELE_Y54F10AM.16 | |||||
| NCBI | gene | 175372 | |||||||
| RefSeq | protein | NM_065174.9 | |||||||
| NM_065176.7 | |||||||||
| SwissProt | UniProtAcc | Q8IA98 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 04 Jan 2022 01:25:27 | WBPerson1983 | Event | Split_from | WBGene00000464 | ||
| 2 | 22 Jun 2022 09:22:34 | WBPerson21950 | Name_change | CGC_name | cone-1 | ||||
| Split_from | WBGene00000464 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cone | ||||||||
| Allele (442) | |||||||||
| Strain | WBStrain00055181 | ||||||||
| WBStrain00055184 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00303739 | ||||||||
| 00303740 | |||||||||
| Contained_in_operon | CEOP3078 | ||||||||
| Ortholog (31) | |||||||||
| Paralog | WBGene00000464 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| Structured_description | Automated_description | Predicted to be involved in intra-Golgi vesicle-mediated transport. Predicted to be located in Golgi membrane. | Paper_evidence | WBPaper00065943 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y54F10AM.16a | |||||||
| Y54F10AM.16b | |||||||||
| Corresponding_transcript | Y54F10AM.16a.1 | ||||||||
| Y54F10AM.16b.1 | |||||||||
| Other_sequence (24) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00106736 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00057402 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00057401 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00107381 | Inferred_automatically | RNAi_primary | |||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (16) | |||||||||
| SAGE_tag (15) | |||||||||
| Map_info | Map | III | |||||||
| Positive | Positive_clone | Y54F10AM | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Interpolated_map_position | III | -12.9134 | |||||||
| Remark | ceh-44 had 3 isoforms, a,b and c. Only the a isoform is a homeobox gene (hence ceh-44) - i.e. only the a-isoform specific exons have the CUT and homeodomain thats the key feature of this protein. The b and c isoforms are a functionally TOTALLY different protein - a Golgi associated protein called CASP. This gene structure is conserved in vertebrates (and it is in vertebrates where this protein has been shown to be a Golgi protein). Thomas Burglin has written about this. See Fig.6 in Burglin et al Int. J. Dev. Biol. 46: 115-123 (2002) Loss and gain of domains during evolution of cut superclass homeobox genes. I would like to argue to call the b and c isoforms (Y54F10AM.4b and Y54F10AM.4c) = cone-1. Decided to rename these Isoforms to have a unique WBGene accession and a new sequence name Y54F10AM.16 | Person_evidence | WBPerson260 | ||||||
| Curator_confirmed | WBPerson1983 | ||||||||
| Method | Gene |
