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WormBase Tree Display for Interaction: WBInteraction000501918

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Name Class

WBInteraction000501918Interaction_typeRegulatoryChange_of_localization
InteractorInteractor_overlapping_geneWBGene00006875Interactor_typeTrans_regulated
Expr_patternExpr2609
Expr2610
TransgeneWBTransgene00000675
ConstructWBCnstr00000672
AntibodyWBAntibody00000653
WBGene00001978Interactor_typeTrans_regulator
WBGene00001980Interactor_typeTrans_regulator
Variation_interactorWBVar00275538Interactor_typeTrans_regulator
Interaction_summaryIn hmp-1 mutants, VAB-9 localized to the adherens junction,whereas the distribution of VAB-9 about the periphery of the junction was punctate and discontinuous. In wild-type, hmp-1 RNAi-treated embryos, VAB-9 GFP was initially distributed about the periphery of the adherens junctions, but was then rapidly mislocalized in hmp-1 RNAi-treated embryos. No VAB-9 junctional localization was observed in animals treated with hmr-1 RNAi.
Detection_methodConstruct
Antibody
Reporter_gene[vab-9::gfp], translational fusion.
Transgene
Regulation_resultPositive_regulateAnatomy_termWBbt:0003672
Subcellular_localizationcell junction
Interaction_RNAiWBRNAi00077351
WBRNAi00077352
PaperWBPaper00005969