WormBase Tree Display for Interaction: WBInteraction000502804
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WBInteraction000502804 | Interaction_type | Regulatory | |||
---|---|---|---|---|---|
Interactor | Interactor_overlapping_gene | WBGene00000103 | Interactor_type | Trans_regulator | |
WBGene00001170 | Interactor_type | Trans_regulated | |||
Variation_interactor | WBVar00091688 | Interactor_type | Trans_regulator | ||
Interaction_summary | In akt-2 loss-of-function mutants, a significant difference was not observed in the induction of these CEP-1 target genes compared with wild-type controls. Thus, although both AKT-1 and AKT-2 regulate DNA-damage-induced apoptosis, only AKT-1 modulates CEP-1/p53 activity as assessed by egl-1 and ced-13 transcriptional activation. | ||||
Detection_method | RT_PCR | ||||
Paper | WBPaper00029085 |