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WormBase Tree Display for Interaction: WBInteraction000502804

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Name Class

WBInteraction000502804Interaction_typeRegulatory
InteractorInteractor_overlapping_geneWBGene00000103Interactor_typeTrans_regulator
WBGene00001170Interactor_typeTrans_regulated
Variation_interactorWBVar00091688Interactor_typeTrans_regulator
Interaction_summaryIn akt-2 loss-of-function mutants, a significant difference was not observed in the induction of these CEP-1 target genes compared with wild-type controls. Thus, although both AKT-1 and AKT-2 regulate DNA-damage-induced apoptosis, only AKT-1 modulates CEP-1/p53 activity as assessed by egl-1 and ced-13 transcriptional activation.
Detection_methodRT_PCR
PaperWBPaper00029085