WormBase Tree Display for Interaction: WBInteraction000503995
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| WBInteraction000503995 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00001665 | Interactor_type | Trans_regulator | |
| Transgene | WBTransgene00004665 | ||||
| Construct | WBCnstr00004647 | ||||
| WBGene00000903 | Interactor_type | Trans_regulated | |||
| Expr_pattern | Expr623 | ||||
| Interaction_summary | G-protein signaling induced by GPA-3 activation suppressed daf-7 transcription. Under the conditions of constant GPA-3 signal activation, pdaf-7::RFP fluorescence was completely turned off. | ||||
| Detection_method | Construct | ||||
| Transgene | |||||
| RT_PCR | |||||
| Regulation_level | Transcriptional | ||||
| Regulation_result | Negative_regulate | Anatomy_term | WBbt:0006751 | ||
| Paper | WBPaper00033456 | ||||
| Remark | gpa-3(syIs25) is a gain-of-function mutant that contains an integrated array of activated gpa-3 construct bearing a single point mutation (Q205L); gpa-3QL. |
