WormBase Tree Display for Interaction: WBInteraction000503998
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WBInteraction000503998 | Interaction_type | Regulatory | Change_of_expression_level | ||
---|---|---|---|---|---|
Interactor | Interactor_overlapping_gene | WBGene00003153 | Interactor_type | Trans_regulated | |
Expr_pattern | Expr8321 | ||||
Transgene | WBTransgene00000246 | ||||
Construct | WBCnstr00000246 | ||||
WBGene00000843 | Interactor_type | Trans_regulator | |||
Variation_interactor | WBVar00000263 | Interactor_type | Trans_regulator | ||
Interaction_summary | cup-2(ar506) (or cup-2 RNAi) results in increased levels of GFP::MCA-3 at the plasma membrane as measured by quantitative microscopy. Western blot analysis of immunoprecipitated GFP::MCA-3 indicated that the increased GFP::MCA-3 signal is due to increased levels of GFP::MCA-3 protein in cup-2 mutant worms. | ||||
Detection_method | Construct | ||||
Reporter_gene | [mca-3::gfp], translational fusion. | ||||
Transgene | |||||
Western | |||||
Regulation_result | Positive_regulate | Subcellular_localization | MCA-3 localize to the plasma membrane of coelomocytes. | ||
Paper | WBPaper00033458 |