WormBase Tree Display for Interaction: WBInteraction000520110
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| WBInteraction000520110 | Interaction_type | Genetic | No_interaction | ||
|---|---|---|---|---|---|
| GI_module_three | Neutral | ||||
| Interactor | Interactor_overlapping_gene | WBGene00001082 | Interactor_type | Non_directional | |
| WBGene00000161 | Interactor_type | Non_directional | |||
| Variation_interactor | WBVar00143530 | Interactor_type | Non_directional | ||
| WBVar01474281 | Interactor_type | Non_directional | |||
| Interaction_summary | Synaptic vesicle proteins are not grossly mislocalized. Synaptotagmin, the vesicular GABA transporter (UNC-47), and synaptogyrin are largely confined to synaptic varicosities in alpha-mu2 adaptin double mutants, although the GFP signal is slightly diffuse in axons. | ||||
| The diameter of the remaining synaptic vesicles is slightly increased in apa-2 and apm-2 apa-2 double mutants. The median diameter of synaptic vesicles in the wild type is 28.4 nm, the diameter in apa-2 mutants (skin rescued) is 30.9 nm, and the diameter inapa-2 apm-2 double mutants (skin rescued) is 31.9 nm. | |||||
| In apa-2 apm-2 double mutants a large vesicle is often observed adjacent to the dense projection and very large vesicles occupy the center of the synaptic varicosity. | |||||
| Throughput | Low_throughput | ||||
| Interaction_phenotype | WBPhenotype:0000847 | ||||
| WBPhenotype:0001323 | |||||
| Paper | WBPaper00042286 |
