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WormBase Tree Display for Interaction: WBInteraction000524605

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Name Class

WBInteraction000524605Interaction_typeGeneticSynthetic
GI_module_oneA_phenotypic
GI_module_threeDiverging
InteractorInteractor_overlapping_geneWBGene00006752Interactor_typeNon_directional
WBGene00004732Interactor_typeNon_directional
Variation_interactorWBVar00090573Interactor_typeNon_directional
WBVar00603900Interactor_typeNon_directional
Interaction_summaryWhile unc-13 is essential for synaptic vesicle exocytosis and thus neurotransmitter release, unc-13(n2813) homozygous animals, like sax-7 null animals, move relatively well and are difficult to distinguish from wild-type animals. In contrast, unc-13(n2813); sax-7 double mutant animals barely move, showing uncoordinated and poor locomotion only when prodded, consistent with a proposed synaptic role for sax-7.
ThroughputLow_throughput
Interaction_phenotypeWBPhenotype:0000643
WBProcessWBbiopr:00000047
PaperWBPaper00046091