WormBase Tree Display for Interaction: WBInteraction000524605
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WBInteraction000524605 | Interaction_type | Genetic | Synthetic | ||
---|---|---|---|---|---|
GI_module_one | A_phenotypic | ||||
GI_module_three | Diverging | ||||
Interactor | Interactor_overlapping_gene | WBGene00006752 | Interactor_type | Non_directional | |
WBGene00004732 | Interactor_type | Non_directional | |||
Variation_interactor | WBVar00090573 | Interactor_type | Non_directional | ||
WBVar00603900 | Interactor_type | Non_directional | |||
Interaction_summary | While unc-13 is essential for synaptic vesicle exocytosis and thus neurotransmitter release, unc-13(n2813) homozygous animals, like sax-7 null animals, move relatively well and are difficult to distinguish from wild-type animals. In contrast, unc-13(n2813); sax-7 double mutant animals barely move, showing uncoordinated and poor locomotion only when prodded, consistent with a proposed synaptic role for sax-7. | ||||
Throughput | Low_throughput | ||||
Interaction_phenotype | WBPhenotype:0000643 | ||||
WBProcess | WBbiopr:00000047 | ||||
Paper | WBPaper00046091 |