WormBase Tree Display for Molecule: WBMol:00005300

WBMol:00005300 Public_name: MG132
  IUPAC: N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-L-leucinamide
  SMILES: [H]C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1
  InChi: InChI=1S/C26H41N3O5/c1-17(2)12-21(15-30)27-24(31)22(13-18(3)4)28-25(32)23(14-19(5)6)29-26(33)34-16-20-10-8-7-9-11-20/h7-11,15,17-19,21-23H,12-14,16H2,1-6H3,(H,27,31)(H,28,32)(H,29,33)/t21-,22-,23-/m0/s1
  InChiKey: TZYWCYJVHRLUCT-VABKMULXSA-N
  Synonym: MG132
    MG-132
    Carbobenzoxy-L-leucyl-L-leucyl-L-leucinal
    N-[(benzyloxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-L-leucinamide
    zLLL
    ZLLL
    Benzyl N-[(1S)-3-methyl-1-[[(1S)-3-methyl-1-[[(2S)-4-methyl-1-oxo-pentan-2-yl]carbamoyl]butyl]carbamoyl]butyl]carbamate
    Z-Leu-Leu-Leu-H Cbz-Leu-Leu-Leu-H
    S2619_Selleck
    MG 132
  DB_info: Database: NLM_MeSH UID C072553
      CTD ChemicalID C072553
      ChEBI CHEBI_ID 75142
      ChemIDplus RN 133407-82-6
  WBProcess: WBbiopr:00000076
  Affects_phenotype_of: Variation: WBVar00143390 WBPhenotype:0001645 Paper_evidence: WBPaper00040652
          Curator_confirmed: WBPerson712
      WBVar00241329 WBPhenotype:0001645 Paper_evidence: WBPaper00040652
          Curator_confirmed: WBPerson712
    RNAi (48)
  Disease_info: Modifies_disease: DOID:9255
    Disease_model_modifier: WBDOannot00001272
  Interaction (14)
  Molecule_use: Cysteine Proteinase Inhibitor | proteasome inhibitor
  Reference: WBPaper00040652
    WBPaper00029081
    WBPaper00041269