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WBPicture0000011054DescriptionHIM-5 is enriched on the autosomes. (A and B) Anti-HIM-5 staining in wild-type germlines. (A) HIM-5 can be seen at low levels in the mitotic zone, accumulates in the transition zone and early pachytene, and decreases mildly upon entry into pachytene and more dramatically in late pachytene. Costaining with anti-XND-1 reveals differences in the accumulation patterns of these two proteins. (B) Enlarged region of late pachytene shows the overlap between XND-1 (green), HIM-5 (magenta), and DNA (blue) showing their exclusion from the X chromosome (orange arrowheads). Similar enrichment is observed in mitotic and early pachytene nuclei (not shown). Bar, 2 um.
NameF6.large_A.jpg
CropCropped_fromWBPicture0000011053
DepictExpr_patternExpr9917
Cellular_componentGO:0005694
AcknowledgmentTemplateWormBase thanks the journal <Journal_URL> for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Reprinted from <Journal_URL>, <Article_URL>. Copyright (<Publication_year>) with permission from <Publisher_URL>
Publication_year2012
Article_URLDOIid10.1534/genetics.111.137463
Journal_URLGenetics
Publisher_URLGSA
ReferenceWBPaper00040572