WormBase Tree Display for Strain: WBStrain00003884
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| WBStrain00003884 | Status | Live | ||
|---|---|---|---|---|
| Genotype | aff-1(tm2214) II. | |||
| Public_name | BP600 | |||
| Contains | Gene | WBGene00016625 | ||
| Variation | WBVar00251141 | |||
| Properties | Outcrossed | x10 | ||
| Mutagen | UV+TMP | |||
| CGC_received | 20 Aug 2007 00:00:00 | |||
| Location | CGC | |||
| Made_by | WBPerson3851 | |||
| Remark | A 1.2 kb deletion in aff-1 (C44B7.3) which introduce stop codon after alanine 47. AFF-1 is a type I membrane protein necessary and sufficient for specific cell fusion events during embryonic and larval development. Temperature sensitivity was not detected. At 20 the fusion of hyp5 in the embryo does not occur as well as anchor cell (AC) fusion, vulval cells fusion of the A and D rings and the terminal fusion between the seam cells late in L4. 6% L1 rod-like lethal and 0% embryonic lethal. Adults are completely Egl, and partially Unc, Pvl. In addition, only 2% of AC in the mutant worms undergo fusion. These animals give very low brood size (16 progeny per worm) and 3.4% of the worms are sterile. This strain gives very small brood size and hence grows slowly. Originally from Shohei Mitani, Tokyo Women's Medical College, Tokyo, Japan. | Inferred_automatically | From CGC strain data | |
| Mutagen:UV/TMP | Curator_confirmed | WBPerson1983 | ||
| Species | Caenorhabditis elegans |
