WormBase Tree Display for Variation: WBVar00000477

WBVar00000477 Evidence: Paper_evidence: WBPaper00028483
  Name: Public_name: bn58
    Other_name: CE27781:p.Arg389Cys
      Y2H9A.1.1:c.1165C>T
    HGVSg: CHROMOSOME_V:g.13436152G>A
  Sequence_details: SMap: S_parent: Sequence: Y2H9A
    Flanking_sequences: ctcgattggtacaagtaccctactggaaat gtggtaatatcaactttgaacgtcttggat
    Mapping_target: Y2H9A
    Type_of_mutation: Substitution: c t Paper_evidence: WBPaper00028483
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: SS
    Status: Live
  Affects: Gene: WBGene00003222
    Transcript: Y2H9A.1.1 (12)
  Genetics: Interpolated_map_position: V 5.34431
    Mapping_data: In_multi_point: 2159
      In_pos_neg_data: 6687
  Description: Phenotype: WBPhenotype:0000154 Paper_evidence: WBPaper00001477
        Curator_confirmed: WBPerson2021
        Remark: bn58 homozygous mothers have a reduced average brood size compared to wild-type controls Paper_evidence: WBPaper00001477
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00001477
          Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00001477
                Curator_confirmed: WBPerson2021
        Phenotype_assay: Temperature: 16 C , 25 C Paper_evidence: WBPaper00001477
              Curator_confirmed: WBPerson2021
      WBPhenotype:0000684 Paper_evidence: WBPaper00001477
        Curator_confirmed: WBPerson2021
        Remark: Mutant progeny exhibit abnormal germline proliferation during development and fail to form mature gametes Paper_evidence: WBPaper00001477
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00001477
          Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00001477
                Curator_confirmed: WBPerson2021
        Maternal
      WBPhenotype:0001504 Paper_evidence: WBPaper00001477
          WBPaper00037131
        Curator_confirmed: WBPerson2021
          WBPerson13811
        Remark: Mes phenotype is not due to abnormalities in P granule staining Paper_evidence: WBPaper00001477
            Curator_confirmed: WBPerson2021
        Penetrance: Complete: Paper_evidence: WBPaper00001477
              Curator_confirmed: WBPerson2021
          Range: 100 100 Paper_evidence: WBPaper00001477
                Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00001477
          Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00001477
                Curator_confirmed: WBPerson2021
        Maternal
        Phenotype_assay: Temperature: 16 C , 25 C Paper_evidence: WBPaper00001477
              Curator_confirmed: WBPerson2021
    Phenotype_not_observed: WBPhenotype:0000052 Paper_evidence: WBPaper00001477
        Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00001477
          Curator_confirmed: WBPerson2021
  Reference: WBPaper00001477
    WBPaper00037131
  Method: Substitution_allele