WormBase Tree Display for Variation: WBVar00089016

WBVar00089016 Name: Public_name: mn63
  Sequence_details: SeqStatus: Pending_curation
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00034146
    Laboratory: SP
    Status: Live
  Affects: Gene: WBGene00005026
  Genetics: Mapping_data: In_pos_neg_data: 1039
        1052
        1064
        1069
        1209
        1230
        1235
        1253
        1401
        3222
  Description: Phenotype: WBPhenotype:0000040 Paper_evidence: WBPaper00003405
        Curator_confirmed: WBPerson2021
        Remark: Some eggs fail to undergo cytokinesis Paper_evidence: WBPaper00003405
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00003405
          Curator_confirmed: WBPerson2021
        Variation_effect: Hypomorph_reduction_of_function: Paper_evidence: WBPaper00003405
            Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000003 PATO:0000460 Paper_evidence: WBPaper00003405
                Curator_confirmed: WBPerson2021
      WBPhenotype:0000059 Paper_evidence: WBPaper00031153
        Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000023 PATO:0000460 Paper_evidence: WBPaper00031153
                Curator_confirmed: WBPerson712
        Maternal: With_maternal_effect: Paper_evidence: WBPaper00031153
            Curator_confirmed: WBPerson712
      WBPhenotype:0000367 Paper_evidence: WBPaper00003405
        Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00003405
          Curator_confirmed: WBPerson2021
        Variation_effect: Hypomorph_reduction_of_function: Paper_evidence: WBPaper00003405
            Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000003 PATO:0000460 Paper_evidence: WBPaper00003405
                Curator_confirmed: WBPerson2021
      WBPhenotype:0000406 Paper_evidence: WBPaper00003405
        Curator_confirmed: WBPerson2021
        Remark: Hatched larvae are lumpy and poorly elongated Paper_evidence: WBPaper00003405
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00003405
          Curator_confirmed: WBPerson2021
        Variation_effect: Hypomorph_reduction_of_function: Paper_evidence: WBPaper00003405
            Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000024 PATO:0000460 Paper_evidence: WBPaper00003405
                Curator_confirmed: WBPerson2021
      WBPhenotype:0000688 Paper_evidence: WBPaper00003405
        Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00003405
          Curator_confirmed: WBPerson2021
        Variation_effect: Hypomorph_reduction_of_function: Paper_evidence: WBPaper00003405
            Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00003405
                Curator_confirmed: WBPerson2021
      WBPhenotype:0000707 Paper_evidence: WBPaper00031153
        Curator_confirmed: WBPerson712
        Remark: Homozygous animals (8/11) from maternally depleted sqv-1 hermaphrodites exhibited short, thick isthmuses. Homozygous animals from heterozygous hermaphrodites do not exhibit pharyngeal development defects. Paper_evidence: WBPaper00031153
            Curator_confirmed: WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0003734 PATO:0000460 Paper_evidence: WBPaper00031153
                Curator_confirmed: WBPerson712
          Life_stage: WBls:0000023 PATO:0000460 Paper_evidence: WBPaper00031153
                Curator_confirmed: WBPerson712
        Maternal: With_maternal_effect: Paper_evidence: WBPaper00031153
            Curator_confirmed: WBPerson712
      WBPhenotype:0000779 Paper_evidence: WBPaper00003405
        Curator_confirmed: WBPerson2021
        Remark: Two- or three-fold embryos are arrested Paper_evidence: WBPaper00003405
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00003405
          Curator_confirmed: WBPerson2021
        Variation_effect: Hypomorph_reduction_of_function: Paper_evidence: WBPaper00003405
            Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000003 PATO:0000460 Paper_evidence: WBPaper00003405
                Curator_confirmed: WBPerson2021
      WBPhenotype:0001360 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: Hermaphrodites lay self-fertilized eggs that do not hatch but eggs are viable if cross-fertilized by mn63 sperm from mn63/+ males. Also Sqv (squashed vulva) phenotype, morphology of L4 vulva abnormal (invagination considerably reduced) Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0006001 Paper_evidence: WBPaper00003405
        Person_evidence: WBPerson261
        Curator_confirmed: WBPerson2021
          WBPerson712
        Remark: Sqv (squashed vulva) phenotype, morphology of L4 vulva abnormal (invagination considerably reduced). Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00003405
          Curator_confirmed: WBPerson2021
        Variation_effect: Hypomorph_reduction_of_function: Paper_evidence: WBPaper00003405
            Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000038 PATO:0000460 Paper_evidence: WBPaper00003405
                Curator_confirmed: WBPerson2021
  Reference: WBPaper00003405
    WBPaper00015154
    WBPaper00021824
    WBPaper00031153
  Method: Allele