Questions, Feedback & Help

Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Variation: WBVar00089869

expand all nodes | collapse all nodes | view schema

WBVar00089869	Name	Public_name	n993
	Sequence_details	SeqStatus	Pending_curation
	Variation_type	Allele
	Origin	Species	Caenorhabditis elegans
		Laboratory	MT
		Status	Live
	Affects	Gene	WBGene00006818
	Description	Phenotype	WBPhenotype:0000179	Paper_evidence	WBPaper00001133
				Curator_confirmed	WBPerson2021
				Remark	HSNs fail to mature and disappear at the later larval stages. Authors comment that unc-86 mutations cause HSNs to degenerate during the L4 stage.	Paper_evidence	WBPaper00001133
						Curator_confirmed	WBPerson2021
				Recessive	Paper_evidence	WBPaper00001133
					Curator_confirmed	WBPerson2021
				EQ_annotations	Anatomy_term	WBbt:0006830	PATO:0000460	Paper_evidence	WBPaper00001133
								Curator_confirmed	WBPerson2021
					Life_stage	WBls:0000038	PATO:0000460	Paper_evidence	WBPaper00001133
								Curator_confirmed	WBPerson2021
			WBPhenotype:0000354	Paper_evidence	WBPaper00001105
				Curator_confirmed	WBPerson2021
				Remark	HSN maturation is abnormal. No hood formation and nucleolar growth is observed	Paper_evidence	WBPaper00001105
						Curator_confirmed	WBPerson2021
				EQ_annotations	Anatomy_term	WBbt:0006830	PATO:0000460	Paper_evidence	WBPaper00001105
								Curator_confirmed	WBPerson2021
					Life_stage	WBls:0000038	PATO:0000460	Paper_evidence	WBPaper00001105
								Curator_confirmed	WBPerson2021
			WBPhenotype:0000425	Paper_evidence	WBPaper00001105
				Curator_confirmed	WBPerson2021
				Remark	Serotonin levels are undetectable in HSNs (determined immunocytochemically).	Paper_evidence	WBPaper00001105
						Curator_confirmed	WBPerson2021
				EQ_annotations	Anatomy_term	WBbt:0006830	PATO:0000460	Paper_evidence	WBPaper00001105
								Curator_confirmed	WBPerson2021
					Life_stage	WBls:0000057	PATO:0000460	Paper_evidence	WBPaper00001105
								Curator_confirmed	WBPerson2021
			WBPhenotype:0000643	Paper_evidence	WBPaper00001105
				Curator_confirmed	WBPerson2021
			WBPhenotype:0001224	Paper_evidence	WBPaper00001105
				Curator_confirmed	WBPerson2021
				Remark	HSNs often extend aberrant axons	Paper_evidence	WBPaper00001105
						Curator_confirmed	WBPerson2021
				EQ_annotations	Anatomy_term	WBbt:0006830	PATO:0000460	Paper_evidence	WBPaper00001105
								Curator_confirmed	WBPerson2021
					Life_stage	WBls:0000057	PATO:0000460	Paper_evidence	WBPaper00001105
								Curator_confirmed	WBPerson2021
			WBPhenotype:0001340	Paper_evidence	WBPaper00001133
				Curator_confirmed	WBPerson2021
				Remark	See Table 1	Paper_evidence	WBPaper00001133
						Curator_confirmed	WBPerson2021
				Penetrance	Complete		Paper_evidence	WBPaper00001133
							Curator_confirmed	WBPerson2021
					Range	100	100	Paper_evidence	WBPaper00001133
								Curator_confirmed	WBPerson2021
				Recessive	Paper_evidence	WBPaper00001133
					Curator_confirmed	WBPerson2021
				EQ_annotations	Life_stage	WBls:0000057	PATO:0000460	Paper_evidence	WBPaper00001133
								Curator_confirmed	WBPerson2021
				Phenotype_assay	Treatment	0.75 mg/ml imipramine	Paper_evidence	WBPaper00001133
							Curator_confirmed	WBPerson2021
					Temperature	24	Paper_evidence	WBPaper00001133
							Curator_confirmed	WBPerson2021
		Phenotype_not_observed	WBPhenotype:0001068	Paper_evidence	WBPaper00001133
				Curator_confirmed	WBPerson2021
				Recessive	Paper_evidence	WBPaper00001133
					Curator_confirmed	WBPerson2021
				EQ_annotations	Life_stage	WBls:0000057	PATO:0000460	Paper_evidence	WBPaper00001133
								Curator_confirmed	WBPerson2021
				Phenotype_assay	Treatment	7.5 mg/ml serotonin	Paper_evidence	WBPaper00001133
							Curator_confirmed	WBPerson2021
					Temperature	24	Paper_evidence	WBPaper00001133
							Curator_confirmed	WBPerson2021
	Reference	WBPaper00001105
		WBPaper00001133
	Method	Allele