WormBase Tree Display for Variation: WBVar00090775
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WBVar00090775 | Evidence | Paper_evidence | WBPaper00024442 | |||||
---|---|---|---|---|---|---|---|---|
Name | Public_name | n3854 | ||||||
Other_name | CE27762:p.Gly565Glu | |||||||
F55B12.3a.1:c.1700G>A | ||||||||
F55B12.3b.1:c.1694G>A | ||||||||
CE25007:p.Gly567Glu | ||||||||
HGVSg | CHROMOSOME_V:g.13822314G>A | |||||||
Sequence_details | SMap | S_parent | Sequence | F55B12 | ||||
Flanking_sequences | TTTGTTCTACTTCTACGATGCTAGCGTGTGCAGTCG | ATCTCGTAACAACACCGAGGAGACCAAAGTTATCCTTCTCGACTTTGATG | ||||||
Mapping_target | F55B12 | |||||||
Type_of_mutation | Substitution | g | a | |||||
SeqStatus | Sequenced | |||||||
Variation_type | Allele | |||||||
Origin | Species | Caenorhabditis elegans | ||||||
Laboratory | MT | |||||||
Status | Live | |||||||
Affects | Gene | WBGene00004767 | ||||||
Transcript | F55B12.3b.1 (12) | |||||||
F55B12.3a.1 (12) | ||||||||
Genetics | Interpolated_map_position | V | 5.62166 | |||||
Description | Phenotype | WBPhenotype:0000006 | Paper_evidence | WBPaper00024442 | ||||
Curator_confirmed | WBPerson712 | |||||||
Penetrance | Incomplete | Fully penetrant at 15C or 20C but only partially penetrant at 25C. | Paper_evidence | WBPaper00024442 | ||||
Curator_confirmed | WBPerson712 | |||||||
Temperature_sensitive | Cold_sensitive | 15 | 20 | Paper_evidence | WBPaper00024442 | ||||
Curator_confirmed | WBPerson712 | |||||||
WBPhenotype:0000683 | Paper_evidence | WBPaper00024442 | ||||||
Curator_confirmed | WBPerson48 | |||||||
Remark | Causes significant masculinization of hermaphrodites. | Paper_evidence | WBPaper00024442 | |||||
Curator_confirmed | WBPerson48 | |||||||
Semi_dominant | Paper_evidence | WBPaper00024442 | ||||||
Curator_confirmed | WBPerson48 | |||||||
Variation_effect | Neomorph_gain_of_function | Paper_evidence | WBPaper00024442 | |||||
Curator_confirmed | WBPerson48 | |||||||
WBPhenotype:0001275 | Paper_evidence | WBPaper00024442 | ||||||
Curator_confirmed | WBPerson48 | |||||||
Remark | Causes increased lin-12 signaling. | Paper_evidence | WBPaper00024442 | |||||
Curator_confirmed | WBPerson48 | |||||||
Reference | WBPaper00024442 | |||||||
Method | Substitution_allele |