WormBase Tree Display for Variation: WBVar00090957
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WBVar00090957 | Name | Public_name | ne19 | ||||||
---|---|---|---|---|---|---|---|---|---|
Sequence_details | SeqStatus | Pending_curation | |||||||
Variation_type | Allele | ||||||||
Origin | Species | Caenorhabditis elegans | |||||||
Laboratory | WM | ||||||||
Status | Live | ||||||||
Affects | Gene | WBGene00003396 | |||||||
Interactor | WBInteraction000000920 | ||||||||
WBInteraction000500033 | |||||||||
WBInteraction000500034 | |||||||||
WBInteraction000521873 | |||||||||
WBInteraction000521875 | |||||||||
WBInteraction000521876 | |||||||||
WBInteraction000524346 | |||||||||
WBInteraction000538510 | |||||||||
Description | Phenotype | WBPhenotype:0000414 | Paper_evidence | WBPaper00003656 | |||||
Curator_confirmed | WBPerson2987 | ||||||||
Remark | 13 out of 22 E blastomeres isolated by laser ablation from mom-4(ne19) mutant embryos failed to produce endoderm and instead produced mesodermal tissues similar to those produced by its (E's) anterior sister MS (data not shown). | Paper_evidence | WBPaper00003656 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
Penetrance | Incomplete | 59% penetrance | Paper_evidence | WBPaper00003656 | |||||
Curator_confirmed | WBPerson2987 | ||||||||
EQ_annotations | Anatomy_term | WBbt:0004804 | PATO:0000460 | Paper_evidence | WBPaper00003656 | ||||
Curator_confirmed | WBPerson2987 | ||||||||
Life_stage | WBls:0000003 | PATO:0000460 | Paper_evidence | WBPaper00003656 | |||||
Curator_confirmed | WBPerson2987 | ||||||||
WBPhenotype:0000472 | Paper_evidence | WBPaper00003656 | |||||||
Curator_confirmed | WBPerson2987 | ||||||||
Remark | The mom-4(ne19) mutation results in 43% of embryos lacking endoderm (Table 1). | Paper_evidence | WBPaper00003656 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
Penetrance | Incomplete | 43% penetrant | Paper_evidence | WBPaper00003656 | |||||
Curator_confirmed | WBPerson2987 | ||||||||
EQ_annotations | Life_stage | WBls:0000003 | PATO:0000460 | Paper_evidence | WBPaper00003656 | ||||
Curator_confirmed | WBPerson2987 | ||||||||
WBPhenotype:0001495 | Paper_evidence | WBPaper00003656 | |||||||
Curator_confirmed | WBPerson2987 | ||||||||
Remark | In lineaged mom-4(ne19) mutant embryos the E lineage exhibited accelerated division timing that was correlated with the corresponding cell transformation phenotype (data not shown). | Paper_evidence | WBPaper00003656 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
EQ_annotations | Anatomy_term | WBbt:0005208 | PATO:0000460 | Paper_evidence | WBPaper00003656 | ||||
Curator_confirmed | WBPerson2987 | ||||||||
Life_stage | WBls:0000003 | PATO:0000460 | Paper_evidence | WBPaper00003656 | |||||
Curator_confirmed | WBPerson2987 | ||||||||
WBPhenotype:0001637 | Paper_evidence | WBPaper00005375 | |||||||
Curator_confirmed | WBPerson2987 | ||||||||
Remark | 46% of mom-4(ne19) embryos lacked an intestine (Table 1) | Paper_evidence | WBPaper00005375 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
Penetrance | Incomplete | 46 | Paper_evidence | WBPaper00005375 | |||||
Curator_confirmed | WBPerson2987 | ||||||||
EQ_annotations | Anatomy_term | WBbt:0005772 | PATO:0000460 | Paper_evidence | WBPaper00005375 | ||||
Curator_confirmed | WBPerson2987 | ||||||||
WBPhenotype:0002216 | Paper_evidence | WBPaper00003656 | |||||||
Curator_confirmed | WBPerson2987 | ||||||||
Remark | In wild-type embryos, the anterior EMS daughter cell (MS) nucleus shows higher levels of POP-1 immunostaining than the posterior sister (E). mom-4(ne19) embryos show equal staining in the nuclei of both anterior and posterior sisters (Figure 1). | Paper_evidence | WBPaper00003656 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
EQ_annotations | Anatomy_term | WBbt:0006876 | PATO:0000460 | Paper_evidence | WBPaper00003656 | ||||
Curator_confirmed | WBPerson2987 | ||||||||
WBbt:0004804 | PATO:0000460 | Paper_evidence | WBPaper00003656 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
WBbt:0004458 | PATO:0000460 | Paper_evidence | WBPaper00003656 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
Life_stage | WBls:0000003 | PATO:0000460 | Paper_evidence | WBPaper00003656 | |||||
Curator_confirmed | WBPerson2987 | ||||||||
Phenotype_not_observed | WBPhenotype:0001133 | Paper_evidence | WBPaper00005375 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
Remark | mom-4(ne19) animals exhibited no embryos with aberrant L-R division of EMS (Table 1) | Paper_evidence | WBPaper00005375 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
EQ_annotations | Anatomy_term | WBbt:0006876 | PATO:0000460 | Paper_evidence | WBPaper00005375 | ||||
Curator_confirmed | WBPerson2987 | ||||||||
Reference | WBPaper00005375 | ||||||||
WBPaper00003656 | |||||||||
Method | Allele |