WormBase Tree Display for Variation: WBVar00091860

WBVar00091860 Evidence: Paper_evidence: WBPaper00032446
  Name: Public_name: ok574
    Other_name: F11D5.3b.1:c.1842-114_*181delinsAATTTAATAGGAAAAAA
      F11D5.3a.1:c.1932-114_*181delinsAATTTAATAGGAAAAAA
    HGVSg: CHROMOSOME_X:g.3323338_3324145delinsAATTTAATAGGAAAAAA
  Sequence_details: SMap: S_parent: Sequence: F11D5
    Flanking_sequences: atagtggtgtaaatttaataggaaaaataa atcggtgcccaattgagaattatcaatgta
    Mapping_target: F11D5
    Type_of_mutation: Insertion: AATTTAATAGGAAAAAA
      Deletion
    PCR_product: OK574_external
      OK574_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00031501
    Laboratory: RB
    Person: WBPerson46
    KO_consortium_allele
    Status: Live
  Affects: Gene: WBGene00017381
    Transcript: F11D5.3b.2 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,3_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        Intron_number: 13-14/14
        Exon_number: 14-15/15
      F11D5.3b.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,3_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F11D5.3b.1:c.1842-114_*181delinsAATTTAATAGGAAAAAA
        cDNA_position: ?-3308
        Intron_number: 12-13/14
        Exon_number: 13-15/15
      F11D5.3a.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,3_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F11D5.3a.1:c.1932-114_*181delinsAATTTAATAGGAAAAAA
        cDNA_position: ?-2608
        Intron_number: 13-14/15
        Exon_number: 14-16/16
    Interactor: WBInteraction000573249
      WBInteraction000573250
  Isolation: Mutagen: TMP/UV
  Description: Phenotype: WBPhenotype:0001224 Paper_evidence: WBPaper00053867
        Curator_confirmed: WBPerson557
        Remark: ddr-2(ok574) mutants exhibit weak guidance defects in axons extending along the major longitudinal axon tracts, most prominently the left ventral nerve cord (VNC). Paper_evidence: WBPaper00053867
            Curator_confirmed: WBPerson557
      WBPhenotype:0001911 Paper_evidence: WBPaper00050526
        Curator_confirmed: WBPerson1068
        EQ_annotations: GO_term: GO:0031103 PATO:0001511 Paper_evidence: WBPaper00050526
                Curator_confirmed: WBPerson1068
    Phenotype_not_observed: WBPhenotype:0001652 Paper_evidence: WBPaper00032446
        Curator_confirmed: WBPerson2021
  Reference: WBPaper00032446
    WBPaper00050526
    WBPaper00053867
  Remark: Last updated on 29 Nov 2002
    Knockout originally requested for F11D5.3 before it was renamed to F11D5.3a
    Sequenced by the C. elegans Gene Knockout Consortium Paper_evidence: WBPaper00041807
  Method: KO_consortium_allele