WormBase Tree Display for Variation: WBVar00093355

WBVar00093355 Name: Public_name: ok2189
    Other_name: Y71G12B.4.1:c.277_368-463del
    HGVSg: CHROMOSOME_I:g.1809624_1810599del
  Sequence_details: SMap: S_parent: Sequence: Y71G12B
    Flanking_sequences: tgggattgtggagaaatgaataagccggat ttgtccgtgtagagtacacgactttcccag
    Mapping_target: Y71G12B
    Type_of_mutation: Deletion
    PCR_product: ok2189_external
      ok2189_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00032413
    Laboratory: RB
    Person: WBPerson46
    KO_consortium_allele
    Status: Live
  Affects: Gene: WBGene00022144
    Transcript: Y71G12B.4.1 VEP_consequence: splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: Y71G12B.4.1:c.277_368-463del
        cDNA_position: 304-?
        CDS_position: 277-?
        Protein_position: 93-?
        Intron_number: 3/4
        Exon_number: 3/5
  Isolation: Mutagen: EMS
  Description: Phenotype: WBPhenotype:0001758 Paper_evidence: WBPaper00053772
        Curator_confirmed: WBPerson40249
        Remark: Reduced number of mature C-terminally amidated neuropeptides, with a higher prevalency of the unprocessed glycine-extended neuropeptides. PGHM-1 is considered as a part of the neuropeptide amidation machinery in C. elegans Paper_evidence: WBPaper00053772
            Curator_confirmed: WBPerson40249
  Reference: WBPaper00053772
  Remark: Sequenced by the C. elegans Gene Knockout Consortium Paper_evidence: WBPaper00041807
  Method: KO_consortium_allele