WormBase Tree Display for Variation: WBVar00094898

WBVar00094898 Evidence: Paper_evidence: WBPaper00035106
    Person_evidence: WBPerson260
  Name: Public_name: ot190
    Other_name: CE18491:p.Ala42Thr
      C08F8.8.1:c.124G>A
    HGVSg: CHROMOSOME_IV:g.11171247G>A
  Sequence_details: SMap: S_parent: Sequence: C08F8
    Flanking_sequences: gcattacagtattttttcctgcgacgggtgt ctggattctttaaagtaagttttaatgttta
    Mapping_target: C08F8
    Type_of_mutation: Substitution: g a Paper_evidence: WBPaper00035106
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00029402
    Laboratory: OH
    Status: Live
  Affects: Gene: WBGene00003657
    Transcript: C08F8.8.1 (12)
  Isolation: Mutagen: EMS
  Genetics: Map: I
    Interpolated_map_position: IV 4.91834
  Description: Phenotype: WBPhenotype:0000031 Paper_evidence: WBPaper00030973
        Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00030973
          Curator_confirmed: WBPerson2021
        Temperature_sensitive: Heat_sensitive: 25C Paper_evidence: WBPaper00030973
              Curator_confirmed: WBPerson2021
        Phenotype_assay: Temperature: 25C Paper_evidence: WBPaper00030973
              Curator_confirmed: WBPerson2021
          Genotype: otIs114 [lim-6p::GFP], ntIs1 [ gcy-5p::GFP] Paper_evidence: WBPaper00030973
              Curator_confirmed: WBPerson2021
      WBPhenotype:0000354 Paper_evidence: WBPaper00035106
        Curator_confirmed: WBPerson2021
        Remark: Loss of bilaterally expressed markers reveals overall differentiation defect of ASE Paper_evidence: WBPaper00035106
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00035106
          Curator_confirmed: WBPerson2021
        Phenotype_assay: Genotype: lim-6 (otIs114) Paper_evidence: WBPaper00035106
              Curator_confirmed: WBPerson2021
      WBPhenotype:0001660 Paper_evidence: WBPaper00030973
          WBPaper00035106
        Curator_confirmed: WBPerson2021
        Remark: ASE asymmetry is disrupted. 2 ASEL Paper_evidence: WBPaper00030973
            Curator_confirmed: WBPerson2021
          lsy-9 mutants display a complex phenotype in the development of left/right asymmetric ASE neurons. Paper_evidence: WBPaper00035106
            Curator_confirmed: WBPerson2021
        Penetrance: Incomplete: Paper_evidence: WBPaper00030973
              Curator_confirmed: WBPerson2021
          Range: 22 26 Paper_evidence: WBPaper00030973
                Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00030973
            WBPaper00035106
          Curator_confirmed: WBPerson2021
        EQ_annotations: Anatomy_term: WBbt:0005663 PATO:0000460 Paper_evidence: WBPaper00030973
                Curator_confirmed: WBPerson2021
        Temperature_sensitive: Heat_sensitive: 25C Paper_evidence: WBPaper00030973
              Curator_confirmed: WBPerson2021
        Phenotype_assay: Temperature: 25C Paper_evidence: WBPaper00030973
              Curator_confirmed: WBPerson2021
          Genotype: otIs114 [lim-6p::GFP], ntIs1 [ gcy-5p::GFP] Paper_evidence: WBPaper00030973
              Curator_confirmed: WBPerson2021
            lim-6 (otIs114) Paper_evidence: WBPaper00035106
              Curator_confirmed: WBPerson2021
    Phenotype_not_observed: WBPhenotype:0000062 Paper_evidence: WBPaper00035106
        Curator_confirmed: WBPerson2021
        Remark: Homozygous viable Paper_evidence: WBPaper00035106
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00035106
          Curator_confirmed: WBPerson2021
  Reference: WBPaper00030973
    WBPaper00035106
  Remark: This used to be an allele of lsy-17. Paper_evidence: WBPaper00035106
  Method: Substitution_allele