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WormBase Tree Display for Variation: WBVar00095111

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Name Class

WBVar00095111EvidencePaper_evidenceWBPaper00002584
NamePublic_namep671
Other_nameCE17780:p.Cys231Arg
F36F2.5.1:c.691T>C
HGVSgCHROMOSOME_I:g.9023031T>C
Sequence_detailsSMapS_parentSequenceC31H5
Flanking_sequencestacatgacatggctctcactagttactttagttttttattcaatgcattttgtattccac
Mapping_targetC31H5
Type_of_mutationSubstitutiontcPaper_evidenceWBPaper00002584
SeqStatusSequenced
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00003905
WBStrain00030780
LaboratoryPR
StatusLive
AffectsGeneWBGene00006525
TranscriptF36F2.5.1 (12)
InteractorWBInteraction000504655
WBInteraction000535464
WBInteraction000535465
WBInteraction000535466
GeneticsInterpolated_map_positionI3.40468
DescriptionPhenotypeWBPhenotype:0000061Paper_evidenceWBPaper00060588
Curator_confirmedWBPerson282
WBPhenotype:0000295Paper_evidenceWBPaper00060588
Curator_confirmedWBPerson282
WBPhenotype:0000481Paper_evidenceWBPaper00059397
Curator_confirmedWBPerson712
RemarkThe repulsion effect of the carvone enantiomers was reduced in tax-4mutants, suggesting that both enantiomers are sensed by tax-4-expressing sensory neurons.Paper_evidenceWBPaper00059397
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00007883Paper_evidenceWBPaper00059397
Curator_confirmedWBPerson712
WBPhenotype:0000637Paper_evidenceWBPaper00060588
Curator_confirmedWBPerson282
WBPhenotype:0001042Paper_evidenceWBPaper00031992
Curator_confirmedWBPerson712
RemarkAll responses to NaCl upsteps and down-steps in ASEL and ASER were eliminated, as assayed by calcium imaging.Paper_evidenceWBPaper00031992
Curator_confirmedWBPerson712
EQ_annotationsAnatomy_termWBbt:0005663PATO:0000460Paper_evidenceWBPaper00031992
Curator_confirmedWBPerson712
Phenotype_assayTemperatureCalcium transients in ASE neurons were measured in response to NaCl concentration steps of 40mM from a baseline of 40 mM.Paper_evidenceWBPaper00031992
Curator_confirmedWBPerson712
WBPhenotype:0001315Paper_evidenceWBPaper00031999
Curator_confirmedWBPerson712
RemarkNo light-induced currents in ASJ were observed.Paper_evidenceWBPaper00031999
Curator_confirmedWBPerson712
EQ_annotationsAnatomy_termWBbt:0005667PATO:0000460Paper_evidenceWBPaper00031999
Curator_confirmedWBPerson712
WBPhenotype:0001438Paper_evidenceWBPaper00001786
Curator_confirmedWBPerson2021
RemarkDefective in chemotaxis to volatile odorants including benzaldehyde, 2-butanone and isoamyl alcohol (Data not shown).Paper_evidenceWBPaper00001786
Curator_confirmedWBPerson2021
EQ_annotationsLife_stageWBls:0000041PATO:0000460Paper_evidenceWBPaper00001786
Curator_confirmedWBPerson2021
WBPhenotype:0001738Paper_evidenceWBPaper00031959
Curator_confirmedWBPerson712
RemarkAnimals were defective in ammonium chemotaxis in water soluble assays when compared to che-1(p679) positive control animals (data not shown).Paper_evidenceWBPaper00031959
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00002091Paper_evidenceWBPaper00031959
Curator_confirmedWBPerson712
Phenotype_assayTreatmentFor the water soluble chemotaxis assay, radial gradients of NH4Cl were established by diffusion in the agar.Paper_evidenceWBPaper00031959
Curator_confirmedWBPerson712
WBPhenotype:0001764Paper_evidenceWBPaper00037908
Curator_confirmedWBPerson557
RemarkThe carbon dioxide-evoked calcium transients of BAG neurons were eliminated.Paper_evidenceWBPaper00037908
Curator_confirmedWBPerson557
WBPhenotype:0001765Paper_evidenceWBPaper00031936
Curator_confirmedWBPerson2021
RemarkAcute CO2 avoidance is eliminatedPaper_evidenceWBPaper00031936
Curator_confirmedWBPerson2021
EQ_annotationsLife_stageWBls:0000057PATO:0000460Paper_evidenceWBPaper00031936
Curator_confirmedWBPerson2021
Phenotype_assayTreatment10% CO2Paper_evidenceWBPaper00031936
Curator_confirmedWBPerson2021
WBPhenotype:0001787Paper_evidenceWBPaper00031999
Curator_confirmedWBPerson712
WBPhenotype:0001790Paper_evidenceWBPaper00032060
Curator_confirmedWBPerson712
RemarkBoth cooling- and warming-evoked thermoreceptor currents in AFD neurons were abolished while voltage-activated currents were essentially left unchanged.Paper_evidenceWBPaper00032060
Curator_confirmedWBPerson712
EQ_annotationsAnatomy_termWBbt:0005662PATO:0000460Paper_evidenceWBPaper00032060
Curator_confirmedWBPerson712
WBPhenotype:0002014Paper_evidenceWBPaper00036207
Curator_confirmedWBPerson712
RemarkGTP-gamma S stimulated inward current in ASJ was absent in the CNG channel mutants. Mastoparan elicited inward currents were blocked.Paper_evidenceWBPaper00036207
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00001587Paper_evidenceWBPaper00036207
Curator_confirmedWBPerson712
WBMol:00004020Paper_evidenceWBPaper00036207
Curator_confirmedWBPerson712
WBPhenotype:0002171Paper_evidenceWBPaper00042397
Curator_confirmedWBPerson1928
RemarkAnimals are defective in chemotaxis towards attractive alkaline pHPaper_evidenceWBPaper00042397
Curator_confirmedWBPerson1928
WBPhenotype:0002378Paper_evidenceWBPaper00054670
Curator_confirmedWBPerson2706
Remarkanimals defective in their ability to avoid OP50 lawns contaminated with Microbacterium nematophilumPaper_evidenceWBPaper00054670
Curator_confirmedWBPerson2706
Phenotype_not_observedWBPhenotype:0001736Paper_evidenceWBPaper00031959
Curator_confirmedWBPerson712
RemarkAnimals showed no defect in acetate chemotaxis in water soluble assays when compared to che-1(p679) positive control animals (data not shown).Paper_evidenceWBPaper00031959
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00005057Paper_evidenceWBPaper00031959
Curator_confirmedWBPerson712
Phenotype_assayTreatmentFor water soluble chemotaxis assays, radial gradients of NaAc were established by diffusion in agar.Paper_evidenceWBPaper00031959
Curator_confirmedWBPerson712
WBPhenotype:0001897Paper_evidenceWBPaper00032087
Curator_confirmedWBPerson2021
RemarkLoss-of-function mutations in the TAX-2 CNG channels do not affect the overall locomotion response to short wavelength lightPaper_evidenceWBPaper00032087
Curator_confirmedWBPerson2021
Variation_effectProbable_null_via_phenotypePaper_evidenceWBPaper00032087
Curator_confirmedWBPerson2021
Reference (15)
RemarkCorrected from pr671 appeared In 2002 European Worm Meeting abstractPerson_evidenceWBPerson712
MethodSubstitution_allele