WormBase Tree Display for Variation: WBVar00095132

WBVar00095132 Name: Public_name: p821
    Other_name: F23B2.4.1:c.2262-1G>A
    HGVSg: CHROMOSOME_IV:g.9138748C>T
  Sequence_details: SMap: S_parent: Sequence: F23B2
    Flanking_sequences: tttgaaataccggaaattaatgacttttca agccatcgaaatatcacataaaatcgatag
    Mapping_target: F23B2
    Type_of_mutation: Substitution: g a Paper_evidence: WBPaper00027360
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00030799
    Laboratory: PR
    Status: Live
  Affects: Gene: WBGene00000906
    Transcript: F23B2.4.1 VEP_consequence: splice_acceptor_variant
        VEP_impact: HIGH
        HGVSc: F23B2.4.1:c.2262-1G>A
        Intron_number: 13/20
    Interactor: WBInteraction000502223
  Genetics: Interpolated_map_position: IV 4.05369
    Mapping_data: In_2_point: 366
        367
      In_multi_point: 1125
  Description: Phenotype: WBPhenotype:0000249 Paper_evidence: WBPaper00000082
        Curator_confirmed: WBPerson712
        Remark: Animals did not avoid high concentrations of fructose of NaCl. Paper_evidence: WBPaper00000082
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00000082
          Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00002899 Paper_evidence: WBPaper00000082
              Curator_confirmed: WBPerson712
            WBMol:00003571 Paper_evidence: WBPaper00000082
              Curator_confirmed: WBPerson712
      WBPhenotype:0000505 Paper_evidence: WBPaper00000932
        Curator_confirmed: WBPerson712
        Remark: Occasional FITC staining of ray sensilla. Paper_evidence: WBPaper00000932
            Curator_confirmed: WBPerson712
      WBPhenotype:0000637 Paper_evidence: WBPaper00000932
        Curator_confirmed: WBPerson712
        Remark: Intermediate response to dauer inducing conditions as assayed through SDS resistance of animals from a crowded, starved plate. Paper_evidence: WBPaper00000932
            Curator_confirmed: WBPerson712
      WBPhenotype:0000649 Paper_evidence: WBPaper00003680
        Curator_confirmed: WBPerson712
        Remark: males are defective in vulva-location behavior Paper_evidence: WBPaper00003680
            Curator_confirmed: WBPerson712
      WBPhenotype:0000679 Paper_evidence: WBPaper00028448
        Curator_confirmed: WBPerson712
        Remark: In a stark contrast to wild type, all IFT mutants examined abnormally accumulate PKD-2::GFP in the ciliary base and in the cilium for those mutants with ciliary axonemes. Paper_evidence: WBPaper00028448
            Curator_confirmed: WBPerson712
      WBPhenotype:0000843 Paper_evidence: WBPaper00000932
        Curator_confirmed: WBPerson712
        Remark: Mating efficiency 1; <1% of WT mating efficiency. Paper_evidence: WBPaper00000932
            Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000056 PATO:0000460 Paper_evidence: WBPaper00000932
                Curator_confirmed: WBPerson712
        Phenotype_assay: Genotype: him-5(e1490) Paper_evidence: WBPaper00000932
              Curator_confirmed: WBPerson712
      WBPhenotype:0001530 Paper_evidence: WBPaper00000932
        Curator_confirmed: WBPerson712
        Remark: Occasional FITC staining of CEP. Paper_evidence: WBPaper00000932
            Curator_confirmed: WBPerson712
      WBPhenotype:0001535 Paper_evidence: WBPaper00000932
        Curator_confirmed: WBPerson712
        Remark: Occasional FITC staining of ADE and PDE. Paper_evidence: WBPaper00000932
            Curator_confirmed: WBPerson712
      WBPhenotype:0002535 Paper_evidence: WBPaper00002087
          WBPaper00000932
        Curator_confirmed: WBPerson48
          WBPerson712
        Remark: Defects in dye filling. Paper_evidence: WBPaper00002087
            Curator_confirmed: WBPerson48
          Frequent weak FITC staining of ADF and ADL but not other amphids or phasmids. Paper_evidence: WBPaper00000932
            Curator_confirmed: WBPerson712
      WBPhenotype:0004004 Paper_evidence: WBPaper00003680
        Curator_confirmed: WBPerson712
        Remark: males are response defective Paper_evidence: WBPaper00003680
            Curator_confirmed: WBPerson712
    Phenotype_not_observed: WBPhenotype:0000315 Paper_evidence: WBPaper00000932
          WBPaper00000082
        Curator_confirmed: WBPerson712
        Remark: Animals showed normal sensitivity to light head and tail tapping with a human eyelash. Paper_evidence: WBPaper00000082
            Curator_confirmed: WBPerson712
      WBPhenotype:0000478 Paper_evidence: WBPaper00000932
          WBPaper00000082
        Curator_confirmed: WBPerson712
        Remark: Animals were able to track isothermally. Paper_evidence: WBPaper00000082
            Curator_confirmed: WBPerson712
      WBPhenotype:0000643 Paper_evidence: WBPaper00000082
        Curator_confirmed: WBPerson712
        Remark: Animals moved normally. Paper_evidence: WBPaper00000082
            Curator_confirmed: WBPerson712
      WBPhenotype:0001015 Paper_evidence: WBPaper00000082
        Curator_confirmed: WBPerson712
        Remark: Animals did not display any major developmental defects compared to N2 animals. Paper_evidence: WBPaper00000082
            Curator_confirmed: WBPerson712
  Reference: WBPaper00000932
    WBPaper00028448
    WBPaper00002087
    WBPaper00003680
    WBPaper00000082
  Method: Substitution_allele