WormBase Tree Display for Variation: WBVar00144023

WBVar00144023 Name: Public_name: e1467
  Sequence_details: SeqStatus: Pending_curation
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00004339
      WBStrain00005521
      WBStrain00007148
      WBStrain00008009
      WBStrain00008469
      WBStrain00008470
      WBStrain00026333
      WBStrain00026576
      WBStrain00026737
      WBStrain00026738
      WBStrain00026745
      WBStrain00026750
      WBStrain00026831
      WBStrain00026838
      WBStrain00026915
      WBStrain00026922
      WBStrain00027000
      WBStrain00027011
      WBStrain00029077
      WBStrain00029078
      WBStrain00029273
      WBStrain00029277
    Laboratory: CB
    Status: Live
  Affects: Gene: WBGene00001864
  Genetics (2)
  Description: Phenotype: WBPhenotype:0000050 Paper_evidence: WBPaper00000179
        Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: 17.6% eggs never hatch, yet are refractile; wild type animals produce 0.8% inviable zygotes. Paper_evidence: WBPaper00000179
            Curator_confirmed: WBPerson712
          some embryonic lethality Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: 25 Person_evidence: WBPerson261
              Curator_confirmed: WBPerson712
        Phenotype_assay: Temperature: 20, 25 Person_evidence: WBPerson261
              Curator_confirmed: WBPerson712
      WBPhenotype:0000154 Paper_evidence: WBPaper00000179
        Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: Animals have an average brood size of 19824 s.d. (6 broods counted), wild type has average brood size 33034 s.d. (8 broods counted). Paper_evidence: WBPaper00000179
            Curator_confirmed: WBPerson712
          brood reduced 64% at 25C Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00000179
                Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: 25 Person_evidence: WBPerson261
              Curator_confirmed: WBPerson712
        Phenotype_assay: Temperature: 20, 25 Person_evidence: WBPerson261
              Curator_confirmed: WBPerson712
      WBPhenotype:0000688 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: additional sterility not due to autosomal nondisjunction Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: 25 Person_evidence: WBPerson261
              Curator_confirmed: WBPerson712
        Phenotype_assay: Temperature: 20, 25 Person_evidence: WBPerson261
              Curator_confirmed: WBPerson712
      WBPhenotype:0000742 Paper_evidence: WBPaper00000179
        Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: Animals exhibit reduced recombination (47%) compared to wild type. Paper_evidence: WBPaper00000179
            Curator_confirmed: WBPerson712
          X chromosome recombination specifically reduced 50% or more, except at left end (increased) Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00000179
                Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: 25 Person_evidence: WBPerson261
              Curator_confirmed: WBPerson712
        Phenotype_assay: Temperature: 20, 25 Person_evidence: WBPerson261
              Curator_confirmed: WBPerson712
      WBPhenotype:0000863 Paper_evidence: WBPaper00000565
          WBPaper00000179
        Curator_confirmed: WBPerson712
        Remark: Male fertility was 66% that of wild type. Paper_evidence: WBPaper00000565
            Curator_confirmed: WBPerson712
          Males exhibit 62.4% wild type fertility. Paper_evidence: WBPaper00000179
            Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000056 PATO:0000460 Paper_evidence: WBPaper00000179
                Curator_confirmed: WBPerson712
      WBPhenotype:0001175 Paper_evidence: WBPaper00000565
          WBPaper00000179
        Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: Male self-progeny make up 23.8% population as measured from 9 broods, 1162 total animals. Paper_evidence: WBPaper00000565
            Curator_confirmed: WBPerson712
          Animals segregate 16.4% males compared to 0.3% segregated by wild type animals. Paper_evidence: WBPaper00000179
            Curator_confirmed: WBPerson712
          at 20C self-progeny 16% XO male, 3% 3X herm, 11% ova are nullo-X as a result of reductional meiotic nondisjunction, score progeny Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: 25 Person_evidence: WBPerson261
              Curator_confirmed: WBPerson712
        Phenotype_assay: Temperature: 20, 25 Person_evidence: WBPerson261
              Curator_confirmed: WBPerson712
        Ease_of_scoring: ES3_Easy_to_score: Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0001583 Paper_evidence: WBPaper00000179
        Curator_confirmed: WBPerson712
        Remark: Animals segregate a small percentage (3.2%) of short animals shown to be 3X hermaphrodites (wild type segregates 0.04% 3X herm.). Paper_evidence: WBPaper00000179
            Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00000179
                Curator_confirmed: WBPerson712
    Phenotype_not_observed: WBPhenotype:0000143 Paper_evidence: WBPaper00000565
        Curator_confirmed: WBPerson712
        Phenotype_assay: Treatment: UV sensitivities were measured as % survival based on radiation dose. Alkaline bleach isolated eggs ranging in age from 30-180 minutes were aliquoted to plates to give between 25-300 survivors/plate. The plated eggs were irradiated at different doses at a rate of 1Jm 10X-2/sec. Irradiated animals were protected from light. Survival was scored as the % animals reaching adulthood 4-6 days after irradiation relative to un-irradiated controls. Paper_evidence: WBPaper00000565
              Curator_confirmed: WBPerson712
      WBPhenotype:0000276 Paper_evidence: WBPaper00000565
        Curator_confirmed: WBPerson712
        Phenotype_assay: Treatment: X-ray sensitivities were measured as % survival based on radiation dose. Alkaline bleach isolated eggs ranging in age from 30-180 minutes were aliquoted to plates to give between 25-300 survivors/plate. The plated eggs were irradiated at different doses at a rate of 470 r/min. Survival was scored as the % animals reaching adulthood 4-6 days after irradiation relative to un-irradiated controls. Paper_evidence: WBPaper00000565
              Curator_confirmed: WBPerson712
      WBPhenotype:0000517 Paper_evidence: WBPaper00000179
        Curator_confirmed: WBPerson712
        Remark: Animals are indistinguishable from wild type in terms of behavior. Paper_evidence: WBPaper00000179
            Curator_confirmed: WBPerson712
      WBPhenotype:0000520 Paper_evidence: WBPaper00000179
        Curator_confirmed: WBPerson712
        Remark: Both hermaphrodites and males are indistinguishable from wild type in terms of superficial anatomy. Paper_evidence: WBPaper00000179
            Curator_confirmed: WBPerson712
      WBPhenotype:0001631 Paper_evidence: WBPaper00000179
        Curator_confirmed: WBPerson712
        Remark: The sex ratio of cross progeny sired by him males does not significantly differ from 1:1. Paper_evidence: WBPaper00000179
            Curator_confirmed: WBPerson712
        EQ_annotations: Life_stage: WBls:0000056 PATO:0000460 Paper_evidence: WBPaper00000179
                Curator_confirmed: WBPerson712
  Reference (11)
  Method: Allele