WormBase Tree Display for Variation: WBVar00144150
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WBVar00144150 | Name | Public_name | e1611 | ||||||
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Sequence_details | SeqStatus | Pending_curation | |||||||
Variation_type | Allele | ||||||||
Origin | Species | Caenorhabditis elegans | |||||||
Strain | WBStrain00004360 | ||||||||
WBStrain00052611 | |||||||||
Laboratory | CB | ||||||||
Status | Live | ||||||||
Affects | Gene | WBGene00003168 | |||||||
Interactor | WBInteraction000005109 | ||||||||
Genetics | Mapping_data | In_multi_point | 426 | ||||||
Description | Phenotype | WBPhenotype:0000179 | Paper_evidence | WBPaper00000502 | |||||
Person_evidence | WBPerson261 | ||||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Cells become vacuolated and die. | Paper_evidence | WBPaper00000502 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
microtubule cells become vacuolated and die in e1611 and e1611/+ | Person_evidence | WBPerson261 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Dominant | Paper_evidence | WBPaper00000502 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Variation_effect | Neomorph_gain_of_function (2) | ||||||||
EQ_annotations | Anatomy_term | WBbt:0005237 | PATO:0000460 | Person_evidence | WBPerson261 | ||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000315 | Paper_evidence | WBPaper00001125 | |||||||
WBPaper00053740 | |||||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPerson31209 | |||||||||
Remark | response to ultrasound stimulation significantly different from wild-type. | Paper_evidence | WBPaper00053740 | ||||||
Curator_confirmed | WBPerson31209 | ||||||||
Dominant | Paper_evidence | WBPaper00001125 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000456 | Paper_evidence | WBPaper00000502 | |||||||
Person_evidence | WBPerson261 | ||||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | touch insensitive | Person_evidence | WBPerson261 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Dominant | Paper_evidence | WBPaper00000502 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Variation_effect | Neomorph_gain_of_function (2) | ||||||||
Ease_of_scoring | ES2_Difficult_to_score | Person_evidence | WBPerson261 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000523 | Paper_evidence | WBPaper00038487 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | While N2 animals traveling perpendicular to the NaCl attractant followed a path that curved with a bias toward the attractant, mutant animals did not regulate their turning; however, like wild-type animals curving decreased over time. | Paper_evidence | WBPaper00038487 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Affected_by | Molecule | WBMol:00003571 | Paper_evidence | WBPaper00038487 | |||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0004027 | Paper_evidence | WBPaper00038487 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Animals exhibited lower escape responses (reversals) and smaller reversal sizes compared to N2 animals upon an initial plate tap, and no change in response to further taps applied at 10 second intervals. | Paper_evidence | WBPaper00038487 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Phenotype_not_observed | WBPhenotype:0000649 | Paper_evidence | WBPaper00003680 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | males are not defective in response or vulva location | Paper_evidence | WBPaper00003680 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0001273 | Paper_evidence | WBPaper00038142 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | The heat avoidance response in the mec-4(e1611) animals iscomparable to N2. | Paper_evidence | WBPaper00038142 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0001715 | Paper_evidence | WBPaper00038487 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Animals regulated pirouette-mediated reversals as a function of direction near food. | Paper_evidence | WBPaper00038487 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0002000 | Paper_evidence | WBPaper00038487 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | After exhibiting an increase in movement on food (induced by transferring a seeded plate to a multi-worm tracker (MWT) apparatus), the population of animals returned to their basal level of spontaneous locomotion speed on food at the same rate as N2 animals. | Paper_evidence | WBPaper00038487 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0004004 | Paper_evidence | WBPaper00003680 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | males are not defective in response or vulva location | Paper_evidence | WBPaper00003680 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Reference (15) | |||||||||
Method | Allele |