WormBase Tree Display for Variation: WBVar00241343
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WBVar00241343 | Evidence | Paper_evidence | WBPaper00032338 | ||||||
---|---|---|---|---|---|---|---|---|---|
Name | Public_name | r398 | |||||||
Sequence_details | SeqStatus | Pending_curation | |||||||
Variation_type | Allele | ||||||||
Origin | Species | Caenorhabditis elegans | |||||||
Laboratory | TR | ||||||||
Status | Live | ||||||||
Affects | Gene | WBGene00006794 | |||||||
Interactor | WBInteraction000500377 | ||||||||
WBInteraction000500378 | |||||||||
WBInteraction000500379 | |||||||||
Description | Phenotype | WBPhenotype:0000436 | Paper_evidence | WBPaper00032338 | |||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | TMD-1 was enriched in the actin aggregates, whereas localization of TMD-1 to the striated myofibrils was greatly diminished compared to wild-type animals where TMD-1 localizes to edges of the actin bands where the pointed ends are concentrated as assayed by immunolocalization. | Paper_evidence | WBPaper00032338 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Phenotype_assay | Treatment | Adult worms were placed in M9 buffer. Then, one beat was counted when a worm swung its head to either the right or left. The total number of beats in 30 seconds was recorded. Worm motility was quantified as described previously (Epstein and Thomson, 1974). Animals were treated with control dsRNA. | Paper_evidence | WBPaper00032338 | |||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0001206 | Paper_evidence | WBPaper00032338 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Animals exhibited a lower frequency of head movements in liquid compared to wild-type animals. | Paper_evidence | WBPaper00032338 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Phenotype_assay | Treatment | Adult worms were placed in M9 buffer. Then, one beat was counted when a worm swung its head to either the right or left. The total number of beats in 30 seconds was recorded. Worm motility was quantified as described previously (Epstein and Thomson, 1974). Animals were treated with control dsRNA. | Paper_evidence | WBPaper00032338 | |||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0001587 | Paper_evidence | WBPaper00032338 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | F-actin aggregated in body wall muscle. | Paper_evidence | WBPaper00032338 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Variation_effect | Hypomorph_reduction_of_function | Paper_evidence | WBPaper00032338 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
EQ_annotations | Anatomy_term | WBbt:0006804 | PATO:0000460 | Paper_evidence | WBPaper00032338 | ||||
Curator_confirmed | WBPerson712 | ||||||||
Reference | WBPaper00032338 | ||||||||
Method | Allele |