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WormBase Tree Display for Variation: WBVar00241343

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Name Class

WBVar00241343EvidencePaper_evidenceWBPaper00032338
NamePublic_namer398
Sequence_detailsSeqStatusPending_curation
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
LaboratoryTR
StatusLive
AffectsGeneWBGene00006794
InteractorWBInteraction000500377
WBInteraction000500378
WBInteraction000500379
DescriptionPhenotypeWBPhenotype:0000436Paper_evidenceWBPaper00032338
Curator_confirmedWBPerson712
RemarkTMD-1 was enriched in the actin aggregates, whereas localization of TMD-1 to the striated myofibrils was greatly diminished compared to wild-type animals where TMD-1 localizes to edges of the actin bands where the pointed ends are concentrated as assayed by immunolocalization.Paper_evidenceWBPaper00032338
Curator_confirmedWBPerson712
Phenotype_assayTreatmentAdult worms were placed in M9 buffer. Then, one beat was counted when a worm swung its head to either the right or left. The total number of beats in 30 seconds was recorded. Worm motility was quantified as described previously (Epstein and Thomson, 1974). Animals were treated with control dsRNA.Paper_evidenceWBPaper00032338
Curator_confirmedWBPerson712
WBPhenotype:0001206Paper_evidenceWBPaper00032338
Curator_confirmedWBPerson712
RemarkAnimals exhibited a lower frequency of head movements in liquid compared to wild-type animals.Paper_evidenceWBPaper00032338
Curator_confirmedWBPerson712
Phenotype_assayTreatmentAdult worms were placed in M9 buffer. Then, one beat was counted when a worm swung its head to either the right or left. The total number of beats in 30 seconds was recorded. Worm motility was quantified as described previously (Epstein and Thomson, 1974). Animals were treated with control dsRNA.Paper_evidenceWBPaper00032338
Curator_confirmedWBPerson712
WBPhenotype:0001587Paper_evidenceWBPaper00032338
Curator_confirmedWBPerson712
RemarkF-actin aggregated in body wall muscle.Paper_evidenceWBPaper00032338
Curator_confirmedWBPerson712
Variation_effectHypomorph_reduction_of_functionPaper_evidenceWBPaper00032338
Curator_confirmedWBPerson712
EQ_annotationsAnatomy_termWBbt:0006804PATO:0000460Paper_evidenceWBPaper00032338
Curator_confirmedWBPerson712
ReferenceWBPaper00032338
MethodAllele