WormBase Tree Display for Variation: WBVar00249541

WBVar00249541 Name: Public_name: tm499
    Other_name: F35G12.10.1:c.550_*26del
    HGVSg: CHROMOSOME_III:g.4594637_4595140del
  Sequence_details: SMap: S_parent: Sequence: F35G12
    Flanking_sequences: gtgcgagaataatttaacaaacgacaaaaa aacgcgttcctgatagtccttgtaaagacc
    Mapping_target: F35G12
    Source_location: 7 CHROMOSOME_III 4594636 4595141 Inferred_automatically: National_Bioresource_Project
    Type_of_mutation: Deletion
    PCR_product: tm499_external
      tm499_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00022690
    Laboratory: FX
    Author: Mitani S
    DB_info: Database: National_Bioresource_Project seq 499
    NBP_allele
    Status: Live
  Affects: Gene: WBGene00000206
    Transcript: F35G12.10.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,stop_lost,3_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F35G12.10.1:c.550_*26del
        cDNA_position: 550-932
        CDS_position: 550-?
        Protein_position: 184-?
        Intron_number: 4/5
        Exon_number: 4-6/6
  Isolation: Mutagen: TMP/UV
  Genetics: Map: III
  Description: Phenotype: WBPhenotype:0000062 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson48
        Remark: Classified as lethal OR sterile by the National Bioresource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson48
      WBPhenotype:0000688 Paper_evidence: WBPaper00028999
        Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson48
          WBPerson557
        Remark: Classified as lethal OR sterile by the National Bioresource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson48
      WBPhenotype:0000812 Paper_evidence: WBPaper00028999
        Curator_confirmed: WBPerson557
        Remark: reduced rate of germline development Paper_evidence: WBPaper00028999
            Curator_confirmed: WBPerson557
    Phenotype_not_observed: WBPhenotype:0000399 Paper_evidence: WBPaper00028999
        Curator_confirmed: WBPerson557
  Reference: WBPaper00028999
  Remark: 28429/28430-28983/28934 (554 bp deletion)
    This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence: WBPaper00041807
  Method: NBP_knockout_allele